<SUBMISSION>
<ACCESSION-NUMBER>0001181431-10-004733
<TYPE>4
<PUBLIC-DOCUMENT-COUNT>1
<PERIOD>20100115
<FILING-DATE>20100126
<DATE-OF-FILING-DATE-CHANGE>20100126
<REPORTING-OWNER>
<OWNER-DATA>
<CONFORMED-NAME>SOON SHIONG PATRICK
<CIK>0001189020
</OWNER-DATA>
<FILING-VALUES>
<FORM-TYPE>4
<ACT>34
<FILE-NUMBER>001-33657
<FILM-NUMBER>10548444
</FILING-VALUES>
</REPORTING-OWNER>
<ISSUER>
<COMPANY-DATA>
<CONFORMED-NAME>Abraxis BioScience, Inc.
<CIK>0001409012
<ASSIGNED-SIC>2834
<IRS-NUMBER>300431735
<STATE-OF-INCORPORATION>DE
<FISCAL-YEAR-END>1231
</COMPANY-DATA>
<BUSINESS-ADDRESS>
<STREET1>11755 WILSHIRE BLVD., 20TH FLOOR
<CITY>LOS ANGELES
<STATE>CA
<ZIP>90025
<PHONE>310-883-1300
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>11755 WILSHIRE BLVD., 20TH FLOOR
<CITY>LOS ANGELES
<STATE>CA
<ZIP>90025
</MAIL-ADDRESS>
<FORMER-COMPANY>
<FORMER-CONFORMED-NAME>Abraxis Biosciences, Inc.
<DATE-CHANGED>20071120
</FORMER-COMPANY>
<FORMER-COMPANY>
<FORMER-CONFORMED-NAME>New Abraxis, Inc.
<DATE-CHANGED>20070806
</FORMER-COMPANY>
</ISSUER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd263551.xml
<DESCRIPTION>ABII FORM 4 SOON 20100115
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-01-15</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001409012</issuerCik>
        <issuerName>Abraxis BioScience, Inc.</issuerName>
        <issuerTradingSymbol>ABII</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001189020</rptOwnerCik>
            <rptOwnerName>SOON SHIONG PATRICK</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ABRAXIS BIOSCIENCE, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>11755 WILSHIRE BLVD., 20TH FLOOR</rptOwnerStreet2>
            <rptOwnerCity>LOS ANGELES</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>90024</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Chairman and CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
                <footnoteId id="F1"/>
            </securityTitle>
            <transactionDate>
                <value>2010-01-15</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>F</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>894</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>41.17</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>11675</value>
                    <footnoteId id="F2"/>
                    <footnoteId id="F3"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>546987</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>ByTrust</value>
                    <footnoteId id="F4"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>8276</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By RSU Plan, LLC</value>
                    <footnoteId id="F5"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>9432714</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By California Capital LP</value>
                    <footnoteId id="F6"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>23035031</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>By GRATs</value>
                    <footnoteId id="F7"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The reporting person is now reporting restricted stock units in Table I, rather than Table II. Accordingly, the number of shares beneficially owned on  Table I includes shares subject to vesting of Restricted Stock Units as set forth in footnotes 2 and 3.</footnote>
        <footnote id="F2">(i) The grant to the reporting person of 8,179 restricted stock units on November 5, 2008, of which 2,045 units vested on March 1, 2009. Of such vested units, 1,313 units were previously timely reported as paid out in common stock and 732 units were previously timely reported as withheld to satisfy the tax withholding obligations related to such vested units. As of the date of this filing, 6,134 shares beneficially owned pursuant to this grant remain subject to vesting.</footnote>
        <footnote id="F3">(ii) The grant to the reporting person of 5,641 restricted stock units on February 3, 2009, of which 1,410 units vested on February 3, 2009. Of such vested units, 891 units were previously timely reported as paid out in common stock and 519 units were previously timely reported as withheld to satisfy the tax withholding obligations related to such vested units. The current transaction reports 894 units withheld to satisfy the tax withholding obligations related to 2,116 units which vested on January 15, 2010, of which 1,222 shares were paid out in common stock. As of the date of this filing, 2,116 shares beneficially owned pursuant to this grant remain subject to vesting.</footnote>
        <footnote id="F4">Shares held by the Soon-Shiong Community Property Revocable Trst U/A/D 3/27/2009.</footnote>
        <footnote id="F5">Entities controlled by the Reporting Person manage RSU Plan, LLC. The Reporting Person disclaims beneficial ownership of the shares held by RSU Plan,  LLC except to the extent of his pecuniary interest in the LLC.</footnote>
        <footnote id="F6">The Reporting Person disclaims beneficial ownership of the shares held by California Capital Limited Partnership except to the extent of his pecuniary interest in the LLC.</footnote>
        <footnote id="F7">Amount beneficially owned includes 5,758,758 shares held by the Patrick Soon-Shiong 2009 GRAT 1 UAD 9/24/2009; 5,758,758 shares held by Patrick Soon-Shiong 2009 GRAT 2 UAD 9/24/2009; 5,758,757 shares held by the Michele B. Soon-Shiong GRAT 1 UAD 9/24/2009; and 5,758,758 shares held by the Michele B. Soon-Shiong GRAT 2 UAD 9/24/2009. The Reporting Person and his spouse disclaim beneficial ownership of the shares held by the GRATs, except to the extent of his or her pecuniary interest therein.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Patrick Soon-Shiong, by Charles Kim, Attorney-in-Fact</signatureName>
        <signatureDate>2010-01-26</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SUBMISSION>
