<SEC-DOCUMENT>0001209191-14-027968.txt : 20140416
<SEC-HEADER>0001209191-14-027968.hdr.sgml : 20140416
<ACCEPTANCE-DATETIME>20140416190018
ACCESSION NUMBER:		0001209191-14-027968
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20140416
FILED AS OF DATE:		20140416
DATE AS OF CHANGE:		20140416

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VITAL THERAPIES INC
		CENTRAL INDEX KEY:			0001280776
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		15222 AVENUE OF SCIENCE, SUITE B
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92128
		BUSINESS PHONE:		858-673-6840

	MAIL ADDRESS:	
		STREET 1:		15222 AVENUE OF SCIENCE, SUITE B
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92128

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Ashley Robert A.
		CENTRAL INDEX KEY:			0001591017

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36201
		FILM NUMBER:		14768401

	MAIL ADDRESS:	
		STREET 1:		C/O VITAL THERAPIES, INC.
		STREET 2:		15010 AVENUE OF SCIENCE, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92128

	FORMER NAME:	
		FORMER CONFORMED NAME:	Ashley Rob
		DATE OF NAME CHANGE:	20131104
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<DESCRIPTION>FORM 3 SUBMISSION
<TEXT>
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<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2014-04-16</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001280776</issuerCik>
        <issuerName>VITAL THERAPIES INC</issuerName>
        <issuerTradingSymbol>VTL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001591017</rptOwnerCik>
            <rptOwnerName>Ashley Robert A.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VITAL THERAPIES, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>15010 AVENUE OF SCIENCE, SUITE 200</rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92128</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Incentive Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.4284</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2022-04-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>93377</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Incentive Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>0.4284</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <value>2022-04-25</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>23344</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Incentive Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2022-09-26</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>6249</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Non-Qualified Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <value>2022-09-26</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>235421</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This stock option was granted on April 1, 2012 and vests over four years. Subject to the optionee continuing to provide services, one forty-eighth of the shares subject to the option vest one month after the vesting commencement date of February 8, 2012, and an additional one forty-eighth of the shares vest at the end of each monthly period thereafter. The option is subject to an early exercise provision and is immediately exercisable.</footnote>
        <footnote id="F2">This stock option was granted on April 25, 2012 and vests over four years. Subject to the optionee continuing to provide services, one forty-eighth of the shares subject to the option vest one month after the vesting commencement date of April 25, 2012, and an additional one forty-eighth of the shares vest at the end of each monthly period thereafter. The option is subject to an early exercise provision and is immediately exercisable.</footnote>
        <footnote id="F3">This stock option was granted on September 26, 2012 and vests over four years. Subject to the optionee continuing to provide services, one forty-eighth of the shares subject to the option vest one month after the vesting commencement date of September 13, 2012, and an additional one forty-eighth of the shares vest at the end of each monthly period thereafter. The option is subject to an early exercise provision and is immediately exercisable.</footnote>
    </footnotes>

    <remarks>Executive Vice President, Chief Technical Officer</remarks>

    <ownerSignature>
        <signatureName>/s/ Michael V. Swanson, by power of attorney</signatureName>
        <signatureDate>2014-04-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>attachment1.htm
<DESCRIPTION>EX-24 DOCUMENT
<TEXT>
<HTML>
<HEAD>
</HEAD>
<BODY>
<PRE>
                                                                      Exhibit 24
                                POWER OF ATTORNEY

        The undersigned, as a Section 16 reporting person of Vital Therapies,
Inc. (the "Company"), hereby constitutes and appoints Terence E. Winters,
Michael V. Swanson, Duane Nash, Aron P. Stern, Anthony Mauriello, and Patrick
Anding the undersigned's true and lawful attorneys-in-fact to:

        1.      complete and execute Forms 3, 4 and 5 and other forms and all
                amendments thereto as such attorneys-in-fact shall in their
                discretion determine to be required or advisable pursuant to
                Section 16 of the Securities Exchange Act of 1934 (as amended)
                and the rules and regulations promulgated thereunder, or any
                successor laws and regulations, as a consequence of the
                undersigned's ownership, acquisition or disposition of
                securities of the Company; and

        2.      do all acts necessary in order to file such forms with the
                Securities and Exchange Commission, any securities exchange or
                national association, the Company and such other person or
                agency as the attorneys-in-fact shall deem appropriate.

        The undersigned hereby ratifies and confirms all that said
attorneys-in-fact and agent shall do or cause to be done by virtue hereof. The
undersigned acknowledges that the foregoing attorneys-in-fact, in serving in
such capacity at the request of the undersigned, is not assuming, nor is the
Company assuming, any of the undersigned's responsibilities to comply with
Section 16 of the Securities Exchange Act of 1934 (as amended).

        This Power of Attorney shall remain in full force and effect until the
undersigned is no longer required to file Forms 3, 4 and 5 with respect to the
undersigned's holdings of and transactions in securities issued by the Company,
unless earlier revoked by the undersigned in a signed writing delivered to the
Company and the foregoing attorneys-in-fact.

        IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to
be executed as of this 20 day of November, 2013.

                                        Signature: /s/ Robert A. Ashley
                                                   -----------------------------

                                        Print Name:  Robert A. Ashley
                                                   -----------------------------
</PRE>
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</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
