<SEC-DOCUMENT>0001209191-14-027973.txt : 20140416
<SEC-HEADER>0001209191-14-027973.hdr.sgml : 20140416
<ACCEPTANCE-DATETIME>20140416190225
ACCESSION NUMBER:		0001209191-14-027973
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		2
CONFORMED PERIOD OF REPORT:	20140416
FILED AS OF DATE:		20140416
DATE AS OF CHANGE:		20140416

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			VITAL THERAPIES INC
		CENTRAL INDEX KEY:			0001280776
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		15222 AVENUE OF SCIENCE, SUITE B
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92128
		BUSINESS PHONE:		858-673-6840

	MAIL ADDRESS:	
		STREET 1:		15222 AVENUE OF SCIENCE, SUITE B
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92128

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Loewen Andrea
		CENTRAL INDEX KEY:			0001591100

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-36201
		FILM NUMBER:		14768413

	MAIL ADDRESS:	
		STREET 1:		C/O VITAL THERAPIES, INC.
		STREET 2:		15010 AVENUE OF SCIENCE, SUITE 200
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92128
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>doc3.xml
<DESCRIPTION>FORM 3 SUBMISSION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2014-04-16</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001280776</issuerCik>
        <issuerName>VITAL THERAPIES INC</issuerName>
        <issuerTradingSymbol>VTL</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001591100</rptOwnerCik>
            <rptOwnerName>Loewen Andrea</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O VITAL THERAPIES, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>15010 AVENUE OF SCIENCE, SUITE 200</rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92128</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>See Remarks</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Incentive Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2023-07-15</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>12500</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Non-Qualified Stock Option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.00</value>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2023-07-15</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>37675</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">This stock option was granted on July 15, 2013 and vests over four years. Subject to the optionee continuing to provide services, one forty-eighth of the shares subject to the option vest one month after the vesting commencement date of July 15, 2013, and an additional one forty-eighth of the shares vest at the end of each monthly period thereafter. The option is subject to an early exercise provision and is immediately exercisable.</footnote>
    </footnotes>

    <remarks>Vice President, Regulatory Affairs and Quality Assurance</remarks>

    <ownerSignature>
        <signatureName>/s/ Michael V. Swanson, by power of attorney</signatureName>
        <signatureDate>2014-04-16</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-24
<SEQUENCE>2
<FILENAME>attachment1.htm
<DESCRIPTION>EX-24 DOCUMENT
<TEXT>
<HTML>
<HEAD>
</HEAD>
<BODY>
<PRE>
                                                                      Exhibit 24
                                POWER OF ATTORNEY

                The undersigned, as a Section 16 reporting person of Vital
        Therapies, Inc. (the "Company"), hereby constitutes and appoints Terence
        E. Winters, Michael V. Swanson, Duane Nash, Aron P. Stern, Anthony
        Mauriello, and Patrick Anding the undersigned's true and lawful
        attorneys-in-fact to:

                1.      complete and execute Forms 3, 4 and 5 and other forms
                        and all amendments thereto as such attorneys-in-fact
                        shall in their discretion determine to be required or
                        advisable pursuant to Section 16 of the Securities
                        Exchange Act of 1934 (as amended) and the rules and
                        regulations promulgated thereunder, or any successor
                        laws and regulations, as a consequence of the
                        undersigned's ownership, acquisition or disposition of
                        securities of the Company; and

                2.      do all acts necessary in order to file such forms with
                        the Securities and Exchange Commission, any securities
                        exchange or national association, the Company and such
                        other person or agency as the attorneys-in-fact shall
                        deem appropriate.

                The undersigned hereby ratifies and confirms all that said
        attorneys-in-fact and agent shall do or cause to be done by virtue
        hereof. The undersigned acknowledges that the foregoing
        attorneys-in-fact, in serving in such capacity at the request of the
        undersigned, is not assuming, nor is the Company assuming, any of the
        undersigned's responsibilities to comply with Section 16 of the
        Securities Exchange Act of 1934 (as amended).

                This Power of Attorney shall remain in full force and effect
        until the undersigned is no longer required to file Forms 3, 4 and 5
        with respect to the undersigned's holdings of and transactions in
        securities issued by the Company, unless earlier revoked by the
        undersigned in a signed writing delivered to the Company and the
        foregoing attorneys-in-fact.

                IN WITNESS WHEREOF, the undersigned has caused this Power of
        Attorney to be executed as of this 20 day of November, 2013.

                                             Signature: /s/ Andrea Loewen
                                                        ------------------------

                                             Print Name:  Andrea Loewen
                                                        ------------------------

</PRE>
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</SEC-DOCUMENT>
