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Condensed Consolidated Statement of Cash Flows - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Cash flows from operating activities:    
Net loss $ (63,933) $ (71,760)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 58 45
Unrealized foreign currency loss 4,217 3,202
Stock-based compensation 6,043 4,483
Common Stock issued in connection with the 4SC royalty settlement (see Note 4) 0 8,625
Changes in operating assets and liabilities:    
Other current assets and prepaid expenses 2,061 (6,305)
Accounts payable 1,151 (261)
Accrued expenses 465 2,760
Other liabilities (102) (341)
Net cash used in operating activities (50,040) (59,552)
Cash flows from investing activities:    
Purchases of property and equipment (113) (48)
Net cash used in investing activities (113) (48)
Cash flows from financing activities:    
Proceeds from exercise of stock options 5 0
Proceeds from shares issued in connection with the Company's employee stock purchase plan 130 0
Net cash provided by financing activities 39,719 42,020
Effect of exchange rate changes on cash and cash equivalents (3,658) 572
Net change in cash and cash equivalents (14,092) (17,008)
Cash and cash equivalents, beginning of period 86,863 127,452
Cash and cash equivalents, end of period 72,771 110,444
Supplemental disclosure of noncash investing and financing activities:    
Common Stock issued in connection with the 4SC royalty settlement (see Note 4) 0 8,625
Operating lease right-of use asset obtained in exchange for lease obligation 0 435
Public Offering    
Cash flows from financing activities:    
Proceeds from Issuance of Common Stock 39,584 0
July 2021 Public Equity Offering    
Cash flows from financing activities:    
Proceeds from Issuance of Common Stock $ 0 $ 42,020