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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
July 2021 Public Equity Offering
At The Market Sales Agreement
4SC Royalty Settlement
October 2022 PIPE Transaction
Common Stock
Common Stock
July 2021 Public Equity Offering
Common Stock
At The Market Sales Agreement
Common Stock
4SC Royalty Settlement
Common Stock
October 2022 PIPE Transaction
Additional Paid-in Capital
Additional Paid-in Capital
July 2021 Public Equity Offering
Additional Paid-in Capital
At The Market Sales Agreement
Additional Paid-in Capital
4SC Royalty Settlement
Additional Paid-in Capital
October 2022 PIPE Transaction
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2020           21,168,240                      
Beginning balance at Dec. 31, 2020 $ 158,785         $ 2         $ 266,823         $ (4,112) $ (103,928)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Net loss (92,945)                               (92,945)
Foreign exchange translation adjustment 3,860                             3,860  
Stock-based compensation 5,949                   5,949            
Issuance of common stock (in shares)             4,500,000 73,221 581,199                
Issuance of common stock   $ 42,020 $ 729 $ 8,625     $ 1         $ 42,019 $ 729 $ 8,625      
Shares issued in connection with the Company's employee stock purchase plan (in shares)           12,758                      
Shares issued in connection with the Company's employee stock purchase plan $ 92                   92            
Ending balance (in shares) at Dec. 31, 2021 26,335,418         26,335,418                      
Ending balance at Dec. 31, 2021 $ 127,115         $ 3         324,237         (252) (196,873)
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Net loss (120,407)                               (120,407)
Foreign exchange translation adjustment 3,287                             3,287  
Stock-based compensation 7,929                   7,929            
Issuance of common stock (in shares)           852   4,204,113   8,696,552              
Issuance of common stock 5   $ 39,584   $ 55,989         $ 1 5   $ 39,584   $ 55,988    
Shares issued in connection with the Company's employee stock purchase plan (in shares)           70,351                      
Shares issued in connection with the Company's employee stock purchase plan $ 182                   182            
Ending balance (in shares) at Dec. 31, 2022 39,307,286         39,307,286                      
Ending balance at Dec. 31, 2022 $ 113,684         $ 4         $ 427,925         $ 3,035 $ (317,280)