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Commitments and Contingencies - Additional Information (Details) - USD ($) $ in Thousands		1 Months Ended				12 Months Ended
	Mar. 31, 2021	Dec. 31, 2022	Aug. 31, 2022	Mar. 31, 2021	May 31, 2016	Dec. 31, 2022	Dec. 31, 2021	Apr. 07, 2020	Apr. 12, 2019
Loss Contingencies [Line Items]
Incremental borrowing rate on operating leases		6.00%				6.00%
Operating and variable lease cost						$ 727	$ 503
Contractual obligation		$ 4,500				$ 4,500
Asset purchase agreement, royalties as percent of aggregated net sales					4.40%
Common stock, shares issued (in shares)		39,307,286				39,307,286	26,335,418		120,070
Common stock issued		$ 4				$ 4	$ 3		$ 1,500
4SC royalty settlement						$ 0	$ 17,250
Immunic AG
Loss Contingencies [Line Items]
Asset purchase agreement, royalties as percent of aggregated net sales	4.40%
4SC royalty settlement	$ 17,250
Royalty settlement agreement, cash payment, percent	50.00%			50.00%
Royalty settlement agreement, shares payment, percent	50.00%			50.00%
Grafelfing, Germany
Loss Contingencies [Line Items]
Lease term (in years)								5 years
Increase in operating lease, right-of-use asset			$ 642	$ 435
New York City
Loss Contingencies [Line Items]
Rent holiday period						6 months
Increase in operating lease, right-of-use asset		$ 332
Incremental borrowing rate on operating leases		8.00%				8.00%

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