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v3.25.1

Subsequent Events (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 3 Months Ended |  |  |
--- | --- | --- | --- | --- | ---
Apr. 09, 2025 | Mar. 31, 2025 | Mar. 31, 2024 | Apr. 30, 2025 | Dec. 31, 2024 | Mar. 04, 2024
Subsequent Event [Line Items] |  |  |  |  |  |
Common stock, par value (in usd per share) |  | $ 0.0001 |  |  | $ 0.0001 | $ 0.0001
Proceeds from issuance of common stock |  | $ 0 | $ 191 |  |  |
Subsequent Event |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Changes in the expanded disability status scale (as a percent) |  |  |  | 20.00% |  |
Reduction in the risk of event in primary progressive multiple sclerosis (as a percent) |  |  |  | 30.00% |  |
Reduction in the risk of event in secondary progressive multiple sclerosis (as a percent) |  |  |  | 15.00% |  |
Reduction in the risk of events in patients without gadolinium-enhancing lesions at baseline (as a percent) |  |  |  | 29.00% |  |
Improvement in brain volume change (as a percent) |  |  |  | 5.00% |  |
Reduction in annualized rate of thalamic brain volume loss (as a percent) |  |  |  | 20.00% |  |
Difference in mean percent between the vidofludimus calcium and placebo (as a percent) |  |  |  | 3.19% |  |
Mean percent change for vidofludimus calcium (as a percent) |  |  |  | (0.22%) |  |
Mean percent change for placebo (as a percent) |  |  |  | 2.97% |  |
Subsequent Event | Securities Purchase Agreement |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Shares issues in private placement transaction (in shares) | 5,666,667 |  |  |  |  |
Common stock, par value (in usd per share) | $ 0.0001 |  |  |  |  |
Sale of stock, price per share (in usd per share) | $ 0.90 |  |  |  |  |
Proceeds from issuance of common stock | $ 5,100 |  |  |  |  |
Subsequent Event | Placement Agency Agreement |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Placement agent agreement, cash fee, percent of gross proceeds from offering (as a percent) | 6.00% |  |  |  |  |
Warrants purchased (in shares) | 283,334 |  |  |  |  |
Shares sold in the Offering (as a percent) | 5.00% |  |  |  |  |
Initial exercise price per share of common stock (in usd per share) | $ 1.125 |  |  |  |  |
Initial exercise price per share (as a percent) | 125.00% |  |  |  |  |
Subsequent Event | Offering |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |
Proceeds from issuance, net of offering expenses | $ 4,600 |  |  |  |  |

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