<SEC-DOCUMENT>0000947263-25-000009.txt : 20251114
<SEC-HEADER>0000947263-25-000009.hdr.sgml : 20251114
<ACCEPTANCE-DATETIME>20251114112415
ACCESSION NUMBER:		0000947263-25-000009
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251114
DATE AS OF CHANGE:		20251114

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Stoke Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001623526
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				471144582
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91051
		FILM NUMBER:		251482900

	BUSINESS ADDRESS:	
		STREET 1:		45 WIGGINS AVENUE
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01730
		BUSINESS PHONE:		781-430-8200

	MAIL ADDRESS:	
		STREET 1:		45 WIGGINS AVENUE
		CITY:			BEDFORD
		STATE:			MA
		ZIP:			01730

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	ASOthera Pharmaceuticals, Inc.
		DATE OF NAME CHANGE:	20141028

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			TORONTO DOMINION BANK
		CENTRAL INDEX KEY:			0000947263
		STANDARD INDUSTRIAL CLASSIFICATION:	COMMERCIAL BANKS, NEC [6029]
		ORGANIZATION NAME:           	02 Finance
		EIN:				135640479
		STATE OF INCORPORATION:			A6
		FISCAL YEAR END:			1031

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G

	BUSINESS ADDRESS:	
		STREET 1:		66 WELLINGTON STREET WEST
		STREET 2:		12TH FLOOR, TD TOWER
		CITY:			TORONTO, ONTARIO
		STATE:			A6
		ZIP:			M5K 1A2
		BUSINESS PHONE:		416-944-6367

	MAIL ADDRESS:	
		STREET 1:		66 WELLINGTON STREET WEST
		STREET 2:		12TH FLOOR, TD TOWER
		CITY:			TORONTO, ONTARIO
		STATE:			A6
		ZIP:			M5K 1A2
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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  <headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0000947263</cik>
          <ccc>XXXXXXXX</ccc>
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      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Stock, $0.0001 par value per share</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>09/30/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001623526</issuerCik>
        <issuerName>Stoke Therapeutics, Inc.</issuerName>
        <issuerCusip>86150R107</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <ns1:street1>45 WIGGINS AVENUE</ns1:street1>
          <ns1:city>BEDFORD</ns1:city>
          <ns1:stateOrCountry>MA</ns1:stateOrCountry>
          <ns1:zipCode>01730</ns1:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(b)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>


      <reportingPersonName>The Toronto-Dominion Bank</reportingPersonName>
      <citizenshipOrOrganization>Z4</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>3173258</soleVotingPower>
        <sharedVotingPower>0</sharedVotingPower>
        <soleDispositivePower>3173258</soleDispositivePower>
        <sharedDispositivePower>0</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>3173258</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
      <classPercent>5.8</classPercent>
      <typeOfReportingPerson>FI</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Stoke Therapeutics, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>45 WIGGINS AVENUE, BEDFORD, MASSACHUSETTS
01730</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>The Toronto-Dominion Bank</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>66 Wellington Street West
12th Floor TD Tower
Toronto, Ontario, Canada
M5K 1A2</principalBusinessOfficeOrResidenceAddress>
        <citizenship>The Toronto-Dominion Bank - CANADA (FEDERAL LEVEL)</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
        <typeOfPersonFiling>FI</typeOfPersonFiling>
        <otherTypeOfPersonFiling>Bank</otherTypeOfPersonFiling>
      </item3>
      <item4>
        <amountBeneficiallyOwned>3,173,258

Between the Date of Event and the filing date, the beneficial ownership of the subject securities was transferred by Cowen Financial Products LLC, an affiliated entity, to the Reporting Person.</amountBeneficiallyOwned>
        <classPercent>5.8</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>The Toronto-Dominion Bank - 3,173,258</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>The Toronto-Dominion Bank - 0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>The Toronto-Dominion Bank - 3,173,258</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>The Toronto-Dominion Bank - 0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
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      <item6>
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        <notApplicableFlag>Y</notApplicableFlag>
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      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>The Toronto-Dominion Bank</reportingPersonName>
      <signatureDetails>
        <signature>Christina Petrou</signature>
        <title>Christina Petrou / Executive Vice President &amp; Chief Operating Officer</title>
        <date>11/13/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
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</DOCUMENT>
</SEC-DOCUMENT>
