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Note 5 - Stockholders' Equity and Dilutive Equity Instruments (Details Textual) - $ / shares
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Out-of-the-money Warrants [Member]    
Class of Warrant or Right, Outstanding (in shares) 5,923,399 5,923,399
Series A Warrants [Member]    
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 57.06 $ 57.06
Series B Warrants [Member]    
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) 62.28 62.28
GLF Equity Warrants [Member]    
Class of Warrant or Right, Exercise Price of Warrants or Rights (in dollars per share) $ 100.00 $ 100.00
In-the-money Warrants and Restricted Stock Units [Member]    
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount (in shares) 2,631,247 3,171,497