<SEC-DOCUMENT>0001648257-24-000072.txt : 20240830
<SEC-HEADER>0001648257-24-000072.hdr.sgml : 20240830
<ACCEPTANCE-DATETIME>20240830061325
ACCESSION NUMBER:		0001648257-24-000072
CONFORMED SUBMISSION TYPE:	6-K
PUBLIC DOCUMENT COUNT:		5
CONFORMED PERIOD OF REPORT:	20240830
FILED AS OF DATE:		20240830
DATE AS OF CHANGE:		20240830

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HUTCHMED (China) Ltd
		CENTRAL INDEX KEY:			0001648257
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			E9

	FILING VALUES:
		FORM TYPE:		6-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37710
		FILM NUMBER:		241265784

	BUSINESS ADDRESS:	
		STREET 1:		48TH FLOOR, CHEUNG KONG CENTER
		STREET 2:		2 QUEEN'S ROAD CENTRAL
		CITY:			HONG KONG
		STATE:			K3
		ZIP:			00000
		BUSINESS PHONE:		852-2121-3888

	MAIL ADDRESS:	
		STREET 1:		48TH FLOOR, CHEUNG KONG CENTER
		STREET 2:		2 QUEEN'S ROAD CENTRAL
		CITY:			HONG KONG
		STATE:			K3
		ZIP:			00000

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Hutchison China MediTech Ltd
		DATE OF NAME CHANGE:	20150716
</SEC-HEADER>
<DOCUMENT>
<TYPE>6-K
<SEQUENCE>1
<FILENAME>hcm-20240830x6k.htm
<DESCRIPTION>6-K
<TEXT>
<!--Enhanced HTML document created with Toppan Merrill Bridge  10.6.125.0--><!--Created on: 8/30/2024 10:02:11 AM (UTC)--><!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"><html><head><meta charset="UTF-8"><title></title></head><body><div style="margin-top:30pt;"></div><div style="max-width:100%;padding-left:4.47%;padding-right:4.47%;position:relative;"><div style="clear:both;max-width:100%;position:relative;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-bottom:1pt;padding-top:1pt;text-align:right;border-bottom:1.0pt solid #000000;border-top:3.0pt solid #000000;margin:0pt 1.5pt 0pt 0pt;"><font style="font-size:1pt;margin-right:0pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">UNITED STATES </b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">SECURITIES AND EXCHANGE COMMISSION</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">Washington, D.C. 20549</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="font-weight:bold;visibility:hidden;">&#8203;</font></p><div style="font-family:'Times New Roman','Times','serif';font-size:11.0pt;margin-bottom:0pt;margin-top:0pt;min-height:1.19em;position:relative;width:100%;"><hr noshade="true" color="#000000" size="1.2" width="25.0%" style="background-color:#000000;color:#000000;height:1.2pt;position:relative;top:0.6em;border:none;margin:0 auto;" align="center"></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="font-size:18pt;font-weight:bold;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-size:16pt;font-weight:bold;">FORM&#160;6-K</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="font-size:16pt;font-weight:bold;visibility:hidden;">&#8203;</font></p><div style="font-family:'Times New Roman','Times','serif';font-size:11.0pt;margin-bottom:0pt;margin-top:0pt;min-height:1.19em;position:relative;width:100%;"><hr noshade="true" color="#000000" size="1.2" width="25.0%" style="background-color:#000000;color:#000000;height:1.2pt;position:relative;top:0.6em;border:none;margin:0 auto;" align="center"></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="font-size:18pt;font-weight:bold;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-size:12pt;font-weight:bold;">REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-size:12pt;font-weight:bold;">SECURITIES EXCHANGE ACT OF 1934</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="font-size:12pt;font-weight:bold;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">For the Month of August 2024</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">Commission File Number: 001-37710</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><div style="font-family:'Times New Roman','Times','serif';font-size:11.0pt;margin-bottom:0pt;margin-top:0pt;min-height:1.19em;position:relative;width:100%;"><hr noshade="true" color="#000000" size="1.2" width="25.0%" style="background-color:#000000;color:#000000;height:1.2pt;position:relative;top:0.6em;border:none;margin:0 auto;" align="center"></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-size:18pt;font-weight:bold;">HUTCHMED (CHINA) LIMITED</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;">(Translation of registrant&#8217;s name into English)</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><div style="font-family:'Times New Roman','Times','serif';font-size:11.0pt;margin-bottom:0pt;margin-top:0pt;min-height:1.19em;position:relative;width:100%;"><hr noshade="true" color="#000000" size="1.2" width="25.0%" style="background-color:#000000;color:#000000;height:1.2pt;position:relative;top:0.6em;border:none;margin:0 auto;" align="center"></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">48th Floor, Cheung Kong Center, 2 Queen&#8217;s Road Central, Hong Kong</b> </p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;">(Address of principal executive offices)</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><div style="font-family:'Times New Roman','Times','serif';font-size:11.0pt;margin-bottom:0pt;margin-top:0pt;min-height:1.19em;position:relative;width:100%;"><hr noshade="true" color="#000000" size="1.2" width="25.0%" style="background-color:#000000;color:#000000;height:1.2pt;position:relative;top:0.6em;border:none;margin:0 auto;" align="center"></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Indicate by check mark whether the registrant files or will file annual reports under cover of Form&#160;20-F or Form&#160;40-F.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;">Form&#160;20-F&#160;&#160;<font style="font-family:'Times New Roman';">&#8999;</font> &#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;&#160;Form&#160;40-F&#160;&#160;<font style="font-family:'Times New Roman';">&#9723;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-bottom:1pt;padding-top:1pt;border-bottom:3.0pt solid #000000;border-top:1.0pt solid #000000;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p><p style="display:none;font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:0pt;margin:0pt;"><font style="font-size:0pt;visibility:hidden;">&#8203;</font></p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-bottom:30pt;margin-left:4.47%;margin-right:4.47%;margin-top:30pt;page-break-after:always;width:91.06%;border-width:0;"><div style="max-width:100%;padding-left:4.47%;padding-right:4.47%;position:relative;"><div style="margin-top:21.6pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></div><div style="clear:both;max-width:100%;position:relative;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">HUTCHMED (CHINA) LIMITED</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">Form&#160;6-K</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><u style="text-decoration-color:#000000;text-decoration-line:underline;text-decoration-style:solid;">EXHIBIT&#160;INDEX</u></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><div><table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;padding-left:0pt;padding-right:0pt;width:100%;" align="center"><tr style="height:1pt;"><td style="vertical-align:bottom;width:11.19%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"></div></div></td><td style="vertical-align:bottom;width:1.64%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"></div></div></td><td style="vertical-align:bottom;width:87.16%;margin:0pt;padding:0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="bottom:0pt;position:absolute;width:100%;"></div></div></td></tr><tr><td style="vertical-align:bottom;width:11.19%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;line-height:1.37;padding-left:7.2pt;text-indent:-7.2pt;margin:0pt;"><b style="font-weight:bold;">Exhibit&#160;No.</b></p></td><td style="vertical-align:bottom;width:1.64%;border-bottom:1px solid transparent;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;line-height:1.37;margin:0pt;"><b style="font-weight:bold;">&#160;&#160;&#160;&#160;</b></p></td><td style="vertical-align:bottom;width:87.16%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;line-height:1.37;margin:0pt;"><b style="font-weight:bold;">Description</b></p></td></tr><tr><td style="vertical-align:top;width:11.19%;border-top:1px solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:bottom;width:1.64%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:87.16%;border-top:1px solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td></tr><tr style="height:18.55pt;"><td style="vertical-align:top;width:11.19%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-left:7.2pt;text-indent:-7.2pt;margin:0pt;">Exhibit 99.1</p></td><td style="vertical-align:top;width:1.64%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:87.16%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Announcement relating to total voting rights</p></td></tr><tr style="height:18.55pt;"><td style="vertical-align:top;width:11.19%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;padding-left:7.2pt;text-indent:-7.2pt;margin:0pt;">Exhibit 99.2</p></td><td style="vertical-align:top;width:1.64%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:87.16%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Announcement relating to update on fruquintinib for second-line gastric cancer in China</p></td></tr></table></div></div><div style="clear:both;margin-bottom:27.35pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:24pt 0pt 0pt 0pt;"><font style="font-size:10pt;">2</font></p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-bottom:30pt;margin-left:4.47%;margin-right:4.47%;margin-top:30pt;page-break-after:always;width:91.06%;border-width:0;"><div style="max-width:100%;padding-left:4.47%;padding-right:4.47%;position:relative;"><div style="margin-top:21.6pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></div><div style="clear:both;max-width:100%;position:relative;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="display:inline-block;text-indent:0pt;width:36pt;"></font><font style="display:inline-block;width:36pt;"></font><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">SIGNATURE</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><div><table style="border-collapse:collapse;font-size:16pt;height:max-content;margin-left:auto;margin-right:auto;padding-left:0pt;padding-right:0pt;width:100%;" align="center"><tr><td style="vertical-align:top;width:50.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td colspan="2" style="vertical-align:top;width:49%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">HUTCHMED (CHINA) LIMITED</p></td></tr><tr><td style="vertical-align:top;width:50.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:7.14%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:41.86%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:50.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:7.14%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:41.86%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:50.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:7.14%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">By:</p></td><td style="vertical-align:top;width:41.86%;border-bottom:1px solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">/s/ Johnny Cheng</p></td></tr><tr><td style="vertical-align:top;width:50.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:7.14%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Name:</p></td><td style="vertical-align:top;width:41.86%;border-top:1px solid #000000;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Johnny Cheng</p></td></tr><tr><td style="vertical-align:top;width:50.99%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:7.14%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Title:</p></td><td style="vertical-align:top;width:41.86%;margin:0pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Chief Financial Officer</p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;">Date: August 30, 2024</p></div><div style="clear:both;margin-bottom:27.35pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:24pt 0pt 0pt 0pt;"><font style="font-size:10pt;">3</font></p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-left:4.47%;margin-right:4.47%;margin-top:30pt;page-break-after:avoid;width:91.06%;border-width:0;"></body></html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>hcm-20240830xex99d1.htm
<DESCRIPTION>EX-99.1
<TEXT>
<!--Enhanced HTML document created with Toppan Merrill Bridge  10.6.125.0--><!--Created on: 8/30/2024 10:02:11 AM (UTC)--><!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"><html><head><meta charset="UTF-8"><title></title></head><body><div style="margin-top:30pt;"></div><div style="max-width:100%;padding-left:4.47%;padding-right:4.47%;position:relative;"><div style="margin-top:21.6pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:right;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></div><div style="clear:both;max-width:100%;position:relative;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;line-height:11pt;text-align:right;margin:0pt;"><b style="font-weight:bold;">Exhibit 99.1</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:right;margin:0pt;"><img src="hcm-20240830xex99d1001.gif" alt="Graphic" style="display:inline-block;height:44.95pt;left:0%;padding-bottom:0.05pt;position:relative;top:0pt;width:160.15pt;"></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="white-space:pre-wrap;">                                                                                                                                                        </font><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><b style="font-weight:bold;">Total Voting Rights</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt;"><font style="display:inline-block;visibility:hidden;width:0pt;">&#8203;</font><br><font style="display:inline-block;visibility:hidden;width:0pt;">&#8203;</font><br><b style="font-weight:bold;">Hong Kong, Shanghai, &amp; Florham Park, NJ &#8212; Friday</b><b style="font-weight:bold;">, August 30, 2024</b><b style="font-weight:bold;">:</b> HUTCHMED (China) Limited (&#8220;HUTCHMED&#8221;) (Nasdaq/AIM: HCM; HKEX: 13) hereby notifies the market that as at August 30, 2024, the issued share capital of HUTCHMED consisted of 871,469,720 ordinary shares of US$0.10 each, with each share carrying one right to vote and with no shares held in treasury.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt;">The above figure of 871,469,720 may be used by shareholders as the denominator for the calculations by which they could determine if they are required to notify their interest in, or a change to their interest in, HUTCHMED under the Financial Conduct Authority&#39;s Disclosure Guidance and Transparency Rules.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt;">For illustrative purposes only, the 871,469,720 ordinary shares would be equivalent to 871,469,720 depositary interests (each equating to one ordinary share) which are traded on AIM or, if the depositary interests were converted in their entirety, equivalent to 174,293,944 American depositary shares (each equating to five ordinary shares) which are traded on Nasdaq.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt;"><font style="font-size:11pt;"><a name="_Hlk528230835"></a></font><b style="font-weight:bold;">About HUTCHMED</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;font-weight:bold;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt;">HUTCHMED (Nasdaq/AIM: HCM; HKEX: 13) is an innovative, commercial-stage, biopharmaceutical company. &#1030;t is committed to the discovery and global development and commercialization of targeted therapies and immunotherapies for the treatment of cancer and immunological diseases. &#1030;t has approximately 5,000 personnel across all its companies, at the center of which is a team of about 1,800 in oncology/immunology. Since inception HUTCHMED has focused on bringing cancer drug candidates from in-house discovery to patients around the world, with its first three medicines now marketed in China, the first of which is also marketed in the US and Europe. For more information, please visit: <u style="color:#0000ff;text-decoration-line:underline;text-decoration-style:solid;">www.hutch-med.com</u> or follow us on <u style="color:#0000ff;text-decoration-line:underline;text-decoration-style:solid;">LinkedIn</u>.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:0pt;"><b style="font-weight:bold;">Contacts</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:10pt;font-weight:bold;visibility:hidden;">&#8203;</font></p><div align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;width:115.96%;padding:2.15pt 0pt 2.15pt 0pt;"><tr style="height:1pt;"><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"></div></div></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:8pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:1pt;visibility:hidden;">&#8203;</font></p></div></div></td></tr><tr style="height:1.4pt;"><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;"><b style="font-weight:bold;">Investor Enquiries</b></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;">+852&#160;2121&#160;8200 / <u style="color:#063b8d;text-decoration-line:underline;text-decoration-style:solid;">ir@hutch-med.com</u></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:8pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;"><b style="font-weight:bold;">Media Enquiries</b></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:8pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0pt 7.7pt;">Ben Atwell / Alex Shaw, FTI&#160;Consulting</p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;">+44&#160;20&#160;3727&#160;1030&#160;/ +44&#160;7771&#160;913&#160;902&#160;(Mobile)&#160;/ +44&#160;7779&#160;545&#160;055&#160;(Mobile)&#160;/ <u style="color:#063b8d;text-decoration-line:underline;text-decoration-style:solid;">HUTCHMED@fticonsulting.com</u> </p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0pt 7.7pt;">Zhou Yi, Brunswick </p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;">+852&#160;9783&#160;6894&#160;(Mobile)&#160;/ <u style="color:#063b8d;text-decoration-line:underline;text-decoration-style:solid;">HUTCHMED@brunswickgroup.com</u></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;"><b style="font-weight:bold;">Nominated Advisor</b></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:8pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 0pt 7.7pt;">Atholl Tweedie / Freddy Crossley / Rupert Dearden, Panmure Liberum</p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;">+44&#160;(20)&#160;7886&#160;2500</p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-left:4.47%;margin-right:4.47%;margin-top:30pt;page-break-after:avoid;width:91.06%;border-width:0;"></body></html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.2
<SEQUENCE>3
<FILENAME>hcm-20240830xex99d2.htm
<DESCRIPTION>EX-99.2
<TEXT>
<!--Enhanced HTML document created with Toppan Merrill Bridge  10.6.125.0--><!--Created on: 8/30/2024 10:02:11 AM (UTC)--><!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"><html><head><meta charset="UTF-8"><title></title></head><body><div style="margin-top:30pt;"></div><div style="max-width:100%;padding-left:4.47%;padding-right:4.47%;position:relative;"><div style="clear:both;max-width:100%;position:relative;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;line-height:11pt;text-align:right;margin:0pt;"><b style="font-weight:bold;">Exhibit 99.2</b></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;line-height:10pt;text-align:right;margin:0pt;"><font style="font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:right;margin:0pt;"><img src="hcm-20240830xex99d2001.gif" alt="Graphic" style="display:inline-block;height:44.95pt;left:0%;padding-bottom:0.05pt;position:relative;top:0pt;width:160.15pt;"></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:center;margin:0pt;"><a name="_Hlk528230835"></a><font style="font-weight:bold;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:12pt;font-weight:bold;text-align:center;margin:0pt 36pt 0pt 36pt;">HUTCHMED Provides Update on Fruquintinib for Second-Line Gastric&#160;Cancer in China</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><b style="font-weight:bold;">Hong Kong, Shanghai &amp; Florham Park, NJ &#8212; Friday, August 30, 2024:</b> HUTCHMED (China) Limited (&#8220;HUTCHMED&#8221;) (Nasdaq/AIM:&#8203;HCM; HKEX:&#8203;13) today announces that it has voluntarily withdrawn its supplemental New Drug Application (&#8220;NDA&#8221;) in China for fruquintinib in combination with paclitaxel for the treatment of second-line advanced gastric or gastroesophageal junction adenocarcinoma and will evaluate a new route forward. Following an additional internal review of the current data package, in light of recent discussions with the National Medical Products Administration of China (&#8220;NMPA&#8221;), HUTCHMED has determined that the submission is unlikely to support an approval in China at this time.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">This supplemental NDA for fruquintinib was based on data from the Phase III FRUTIGA study, which was declared positive due to a statistically significant improvements in many clinically meaningful endpoints, including progression-free survival (&#8220;PFS&#8221;), which served as one of two primary endpoints. However, while an improvement was also observed in the second primary endpoint of median overall survival (&#8220;OS&#8221;), it was not statistically significant. Extensive subsequent analyses conducted indicate that, although the high and imbalanced proportion of patients receiving subsequent antitumor therapies confounded the OS effect, fruquintinib plus paclitaxel demonstrated meaningful clinical benefit and favorable OS trends through a variety of models. Furthermore, no new safety signals were observed, and fruquintinib plus paclitaxel showed a tolerable safety profile. However, it became clear from dialogue with the Centre for Drug Evaluation (CDE) of the NMPA and its external committee members that the current understanding and interpretation of the OS results could not serve as the basis of the supplemental NDA approval, and that further work needs to be undertaken. </p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Dr Weiguo Su, Chief Executive Officer and Chief Scientific Officer of HUTCHMED, commented, &#8220;Whilst disappointed by this outcome, we remain optimistic about the utility of fruquintinib in the treatment of gastric cancer. The data set from FRUTIGA demonstrates that fruquintinib plus paclitaxel could offer a promising new treatment option to certain patients in future, and we are driven to investigate this possibility thoroughly. We look forward to evaluating a path forward and would like to thank both the patients and principal investigators who took part in this study for contributing to a better understanding of this devastating disease.&#8221; </p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Dr Rui-Hua Xu, Professor at the Department of Medical Oncology, Sun Yat-sen University Cancer Center, Guangzhou, added, &#8220;Gastric cancer is the fifth most common cancer worldwide and patients in China are currently underserved by available treatment options. Although the current data package would not support approval on this occasion, the Phase III study demonstrated clear benefits of this fruquintinib combination across many clinically meaningful endpoints and the team are committed to evaluating all options. Promising subgroup analyses are helping us to better understand how we can effectively combat this disease, and we remain hopeful that this study forms part of an important journey to a much-needed new therapy.&#8221;</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Fruquintinib is approved in China, the US and Europe for the treatment of previously-treated patients with metastatic colorectal cancer (&#8220;CRC&#8221;), and <a name="_Hlk174355188"></a>regulatory applications for this indication are progressing as expected in over a dozen jurisdictions. It works as an anti-cancer therapy by blocking tumor angiogenesis, a proliferation of blood vessels that is critical for cancer growth. It is a selective oral inhibitor of vascular endothelial growth factor receptors (&#8220;VEGFRs&#8221;) 1, 2 and 3, and this pathway plays a key role in the pathogenesis of many solid tumors including gastric cancer. </p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">An NDA in China for fruquintinib in combination with sintilimab in endometrial cancer was accepted with priority review status in April 2024, and a Phase III trial in China of fruquintinib in combination with sintilimab in renal cell carcinoma was fully enrolled in December 2023.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-bottom:30pt;margin-left:4.47%;margin-right:4.47%;margin-top:30pt;page-break-after:always;width:91.06%;border-width:0;"><div style="max-width:100%;padding-left:4.47%;padding-right:4.47%;position:relative;"><div style="clear:both;max-width:100%;position:relative;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">About the Phase III FRUTIGA Trial</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">FRUTIGA (NCT03223376) was a 1:1 randomized, double-blind, Phase III study conducted across 35 sites in China. It evaluated fruquintinib in combination with paclitaxel chemotherapy, compared with paclitaxel monotherapy, for second-line treatment in 703 patients with advanced gastric or gastroesophageal junction adenocarcinoma. The study was declared positive due to a statistically significant improvement in progression-free survival (&#8220;PFS&#8221;), one of two dual primary endpoints. Median PFS for patients who received fruquintinib plus paclitaxel was 5.6 months, compared to 2.7 months for those who received paclitaxel monotherapy (stratified hazard ratio [&#8220;HR&#8221;] = 0.569;&#160;<i style="font-style:italic;">p</i>&#160;&lt;&#160;0.0001). An improvement was also observed in the dual primary endpoint of median overall survival (OS), (9.6 months vs. 8.4 months) but this was not statistically significant. Fruquintinib plus paclitaxel demonstrated statistically significant improvements in multiple other endpoints including objective response rate (ORR), disease control rate (DCR) and duration of response (DoR). It was well tolerated, with a safety profile consistent with expectations and previously reported studies.<sup style="font-size:8.25pt;vertical-align:top;">1 </sup></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Results were published in <i style="font-style:italic;">Nature Medicine</i> and presented at the ASCO 2024 Annual Meeting, concluding that fruquintinib plus paclitaxel could be a promising second-line treatment option for patients with advanced gastric or gastro&#173;esophageal adenocarcinoma, who have failed fluoropyrimidine- or platinum-containing chemotherapy. </p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">About Gastric Cancer</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Gastric cancer is a cancer that starts in the stomach. It is the fifth most common cancer worldwide in 2022. It was estimated to have caused approximately 660,000 deaths worldwide<a name="_Ref83129432"></a>.<sup style="font-size:8.25pt;vertical-align:top;">2</sup> In China, it was estimated that over 359,000 people were diagnosed with gastric cancer, and approximately 260,000 people died from gastric cancer.<sup style="font-size:8.25pt;vertical-align:top;">3</sup></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">About Fruquintinib</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Fruquintinib is a selective oral inhibitor of VEGFR-1, -2 and -3. VEGFR inhibitors play a pivotal role in inhibiting tumor angiogenesis. Fruquintinib was designed to have enhanced selectivity that limits off-target kinase activity, allowing for high drug exposure, sustained target inhibition, and flexibility for the potential use as part of combination therapy. Fruquintinib has demonstrated a manageable safety profile and is being investigated in combinations with other anti-cancer therapies.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">About Fruquintinib Approval for metastatic CRC in China</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Fruquintinib is approved for marketing in China, where it is co-marketed by HUTCHMED and Lilly under the brand name ELUNATE<sup style="font-size:8.25pt;vertical-align:top;">&#174;</sup>. It was included in the China National Reimbursement Drug List (NRDL) in January 2020. The approval was based on data from the FRESCO study, a Phase III pivotal registration trial of fruquintinib in 416 patients with metastatic CRC in China, which were published in The Journal of the American Medical Association, JAMA. Since its launch, fruquintinib has benefited over 100,000 patients in China. </p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">About Takeda and Fruquintinib Approval for metastatic CRC outside China</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">Takeda has the exclusive worldwide license to further develop, commercialize, and manufacture fruquintinib outside of mainland China, Hong Kong and Macau. For the treatment of metastatic CRC, fruquintinib received approval in the US in November 2023 and in Europe in June 2024, where it is marketed by Takeda under the brand name FRUZAQLA<sup style="font-size:8.25pt;vertical-align:top;">&#174;</sup>. The approvals were based on data from two large, randomized, controlled Phase III trials: the multi-regional FRESCO-2 trial, data from which were published in <i style="font-style:italic;">The Lancet</i>, and the FRESCO trial conducted in China. The trials investigated fruquintinib plus best supportive care versus placebo plus best supportive care in patients with previously treated metastatic CRC. Both FRESCO and FRESCO-2 met their primary and key secondary efficacy endpoints and showed consistent benefit among a total of 734 patients treated with fruquintinib. Safety profiles were consistent across trials. Other regulatory applications for this indication are progressing as expected in Japan and in many other jurisdictions.</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;font-weight:bold;text-align:justify;margin:0pt 0pt 12pt 0pt;">About HUTCHMED</p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;">HUTCHMED (Nasdaq/AIM:&#8203;HCM; HKEX:&#8203;13) is an innovative, commercial-stage, biopharmaceutical company. It is committed to the discovery and global development and commercialization of targeted therapies and immunotherapies for the treatment of cancer and immunological diseases. It has approximately 5,000 personnel across all its companies, at the center of which is a team of about 1,800 in oncology/&#8203;immunology. Since inception it has focused on bringing cancer drug candidates from in-house discovery to patients around the world, with its first three medicines marketed in China, the first of which is also marketed in the US and Europe. For more information, please visit: www.hutch-med.com or follow us on LinkedIn.</p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-bottom:30pt;margin-left:4.47%;margin-right:4.47%;margin-top:30pt;page-break-after:always;width:91.06%;border-width:0;"><div style="max-width:100%;padding-left:4.47%;padding-right:4.47%;position:relative;"><div style="clear:both;max-width:100%;position:relative;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Arial','Helvetica','sans-serif';font-size:8pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"><font style="font-family:'Times New Roman','Times','serif';font-style:italic;">Forward-Looking Statements</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;font-style:italic;text-align:justify;margin:0pt;">This announcement contains forward-looking statements within the meaning of the &#8220;safe harbor&#8221; provisions of the US Private Securities Litigation Reform Act of 1995. These forward-looking statements reflect HUTCHMED&#8217;s current expectations regarding future events, including its expectations regarding the therapeutic potential of fruquintinib for the treatment of patients with advanced gastric cancer and the further clinical development of fruquintinib in this and other indications. Forward-looking statements involve risks and uncertainties. Such risks and uncertainties include, among other things, assumptions regarding the sufficiency of clinical data to support NDA approval of fruquintinib for the treatment of patients with advanced gastric cancer in China, the US, Europe, Japan, Australia or other jurisdictions, its potential to gain expeditious approvals from regulatory authorities, the safety profile of fruquintinib, HUTCHMED&#8217;s ability to fund, implement and complete its further clinical development and commercialization plans for fruquintinib. In addition, as certain studies rely on the use of other drug products such as paclitaxel, tislelizumab and sintilimab as combination therapeutics with fruquintinib, such risks and uncertainties include assumptions regarding the safety, efficacy, supply and continued regulatory approval of these therapeutics. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. For further discussion of these and other risks, see HUTCHMED&#8217;s filings with the US Securities and Exchange Commission, on AIM and on The Stock Exchange of Hong Kong Limited. HUTCHMED undertakes no obligation to update or revise the information contained in this announcement, whether as a result of new information, future events or circumstances or otherwise.</p><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;font-style:italic;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;font-style:italic;text-align:justify;margin:0pt;"><font style="font-style:normal;visibility:hidden;">&#8203;</font></p><p style="font-family:'Arial','Helvetica','sans-serif';font-size:8pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"><b style="font-size:11pt;font-weight:bold;"><a name="_Hlk136438441"></a></b><font style="font-family:'Times New Roman','Times','serif';font-style:italic;">Medical Information</font></p><p style="font-family:'Arial','Helvetica','sans-serif';font-size:8pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"><i style="font-family:'Times New Roman','Times','serif';font-style:italic;font-weight:normal;">This announcement contains information about products that may not be available in all countries, or may be available under different trademarks, for different indications, in different dosages, or in different strengths. Nothing contained herein should be considered a solicitation, promotion or advertisement for any prescription drugs including the ones under development.</i></p><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;font-style:italic;text-align:justify;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Arial','Helvetica','sans-serif';font-size:8pt;font-weight:bold;margin:0pt 0pt 12pt 0pt;"><font style="font-family:'Times New Roman','Times','serif';font-style:italic;">Inside Information</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;"><i style="font-style:italic;">This announcement contains inside information for the purposes of Article 7 of Regulation (EU) No 596/2014 (as it forms part of retained EU law as defined in the European Union (Withdrawal) Act 2018).</i><i style="font-style:italic;"> </i></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:9pt;font-style:italic;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;text-align:justify;margin:0pt;"><font style="font-size:8pt;font-style:italic;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;text-align:justify;margin:10pt 0pt 10pt 0pt;"><b style="font-weight:bold;">CONTACTS</b></p><div align="left"><table style="border-collapse:collapse;font-size:16pt;height:max-content;width:100%;padding:2.15pt 0pt 2.15pt 0pt;"><tr style="height:1pt;"><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"></div></div></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><div style="height:1pt;overflow:hidden;overflow-wrap:break-word;position:relative;"><div style="position:absolute;top:0pt;width:100%;"></div></div></td></tr><tr style="height:1.4pt;"><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;text-align:justify;margin:0pt;"><b style="font-weight:bold;">Investor Enquiries</b></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt;">+852&#160;2121&#160;8200 / <u style="color:#0000ff;text-decoration-line:underline;text-decoration-style:solid;">ir@hutch-med.com</u> </p></td></tr><tr style="height:0.9pt;"><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;text-align:justify;margin:0pt;"><b style="font-weight:bold;">Media Enquiries</b></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt 0pt 0pt 7.7pt;">Ben Atwell / Alex Shaw, FTI&#160;Consulting</p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt;">+44&#160;20&#160;3727&#160;1030&#160;/ +44&#160;7771&#160;913&#160;902&#160;(Mobile)&#160;/ +44&#160;7779&#160;545&#160;055&#160;(Mobile)&#160;/ <u style="color:#0000ff;text-decoration-line:underline;text-decoration-style:solid;">HUTCHMED@fticonsulting.com</u> </p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt 0pt 0pt 7.7pt;">Zhou Yi, Brunswick </p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt;">+852&#160;9783&#160;6894&#160;(Mobile)&#160;/ <u style="color:#0000ff;text-decoration-line:underline;text-decoration-style:solid;">HUTCHMED@brunswickgroup.com</u></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;text-align:justify;margin:0pt;"><b style="font-weight:bold;">Nominated Advisor</b></p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="font-size:9pt;visibility:hidden;">&#8203;</font></p></td></tr><tr><td style="vertical-align:top;width:29.56%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt 0pt 0pt 7.7pt;">Atholl Tweedie&#160;/ Freddy&#160;Crossley&#160;/ Rupert&#160;Dearden, Panmure&#160;Liberum</p></td><td style="vertical-align:top;width:70.43%;margin:0pt;padding:2.15pt 0pt 2.15pt 0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:9pt;margin:0pt;">+44&#160;(20)&#160;7886 2500</p></td></tr></table></div><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:11pt;margin:0pt;"><font style="color:#404040;font-size:10pt;visibility:hidden;">&#8203;</font></p><p style="font-family:'Times New Roman','Times','serif';font-size:10pt;margin:0pt;"><font style="color:#404040;">____________________</font></p><table border="0" cellpadding="0" cellspacing="0"><tr><td style="vertical-align:text-top;white-space:nowrap;width:8.5pt;padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin-bottom:3pt;margin-top:0pt;"><sup style="font-size:6pt;vertical-align:top;">1</sup> </p></td><td style="padding:0pt;"><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin-bottom:3pt;margin-top:0pt;">Wang F, et al. Fruquintinib plus paclitaxel versus placebo plus paclitaxel as second-line therapy for advanced gastric or gastro-esophageal junction adenocarcinoma (FRUTIGA): a randomized, multicenter, double-blind, placebo-controlled, phase 3 study [published online ahead of print, 2024 Jun 1]. <i style="font-style:italic;">Nat Med</i>. 2024. DOI: 10.1038/s41591-024-02989-6.</p></td></tr></table><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt 0pt 3pt 0pt;"><sup style="font-size:6pt;vertical-align:top;">2</sup> The Global Cancer Observatory, Stomach Cancer Fact Sheet<font style="white-space:pre-wrap;">.  Accessed August 14, 2024. </font></p><p style="font-family:'Times New Roman','Times','serif';font-size:8pt;margin:0pt;"><sup style="font-size:6pt;vertical-align:top;">3</sup> The Global Cancer Observatory, China Fact Sheet. Accessed August 14, 2024.</p></div></div><hr style="background-color:#000000;clear:both;color:#000000;height:2pt;line-height:0;margin-left:4.47%;margin-right:4.47%;margin-top:30pt;page-break-after:avoid;width:91.06%;border-width:0;"></body></html>
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>hcm-20240830xex99d1001.gif
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 hcm-20240830xex99d1001.gif
M1TE&.#EAU0 \ /8      (X479,>9)4A9I8E:9@G:IHM;ILO<)PQ<:$\>*5$
M?M(M<],Q==0V>=8\??$I;O$N<O(U=O(W>/([>O)"?Z9&@*=)@:E+@ZM1AZU5
MBJ]8C+%<C[)?D+1CD[=IE[=IF+ALFKMRG;UVH;YXHM=!@-A)A=M4C=U=D]YD
MF,%]IO-$@?-+A?-/B/13B_19C_1<D?5AE?5GF/5KF^)UH^-ZIN1_JO9UHO9Y
MI?9^J,2$JL:)KLB.L<N3M,^:N=&>O-*AON6%K>:(K^:,LNB2MNB5N.J;O/>&
MK?>(K_>+L?B.L_B2MOB6N/B9NOFAO]2EP=>LQ=BMQMNTR]VYSMZ[T.RCP>VJ
MQN^SS."_T_FEPOFJQ?FOR?JSS/JXS_&[TOJ\TN+#U>3'V.7*VNC/WO+"UO3*
MW/O#UOO&V/O,W?S0W^O5XNW9Y>_>Z/;7Y/?=Z?S2X?S:YOK>Z?+D[/3H[_OC
M[/WH[_;L\OWL\O?P]/KR]OWV^?[^_@                   "'Y! $
M+     #5 #P 1@C_ /4('$BPH,&#"!,J7,BPH<.'$",F3,-!08<T$C-JW,BQ
MH\>/( _FT9-#  (#!P:,T(/'QX<18@;FL3(#"!F%<X3,*&)GH)TE-I;T#$FT
MJ-&C'4N>1" @QQ23!A 0J*!'S ('6!N8F%,":]8V0JXZ(+$@B!XE$5104 $A
MB1<(:E5,>(&TKMV[=T>"'+DDK0H5$7 <+$"X  $$>!)>$$#XL)R!&1@WCHDP
M<F$",3<P)D"@<>?&ACEW-B @BAZ]7SP@&#! 0.O7"#*LT>-$<@$!*_463#/
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MZNKEZPG 0Y,\VZ?'S_H5P)]!4K9:I4QZ7)EV@@5UZ>E2:C0TIG[K>6J[A@F
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M$J"(&U%__)< "; J(-"+!G(I#45-D(404-54$V1AI\(E32,DG<6,\(,2"*
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:V:JMXBJN33 2;R"MXZJM6; %9P"@'Q$0 #L!

end
</TEXT>
</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>hcm-20240830xex99d2001.gif
<DESCRIPTION>GRAPHIC
<TEXT>
begin 644 hcm-20240830xex99d2001.gif
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MH''GQH8Y=RX0 $H>O5XZ'! @($#KUP<PJ,G31#*! "OU%D0CP/#M"P1K0)!
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M^.2*"1%DT&%XQX.(:G&+CP*6B/$>7OB28#  K3(?45",9--J;_E0##510B(
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M \U5$&"0 QJPCEF& 2A@!0R%$$V0 SL@JE33$&'  QY@ <!J 1D@ CS 'V&
MJJ+J% D1!\@:-3Y $%V0!$LPK4I@C0OQ!DHPK4N0!,$Y$&:P!-FJK>(JKDPP
2$FX@K>.JK5B@!68 H!\1$  [

end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
