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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $) | 12 Months Ended | 190 Months Ended
--- | --- | ---
Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011 | Dec. 31, 2013
Cash flows from operating activities |  |  |  |
Net Loss | $ (10,657,009) | $ (13,092,387) | $ (10,856,547) | $ (93,038,863)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |  |
Write off of intangible assets | 0 | 0 | 0 | 505,000
Settlement of litigation and debt | (346) | (239,775) | (175,934) | (1,578,375)
Settlement of debt due Morale/Matthews | 0 | 0 | 0 | 927,903
Stock based compensation expense | 4,764,964 | 2,070,426 | 2,240,961 | 13,011,507
Issuance of common stock for services | 49,000 | 1,228,250 | 862,000 | 9,312,038
Issuance of common stock as settlement | 3,108,347 | 0 | 0 | 3,108,347
Issuance of warrants and options for legal settlement | 0 | 0 | 0 | 36,457
Issuance of warrants for financing fees | 0 | 0 | 0 | 153,501
Issuance of warrants and options for consulting fees | 100,694 | 641,747 | 411,888 | 1,280,329
Increase in convertible notes related to default | 0 | 0 | 2,795 | 299,274
Interest on related party loans | 0 | 0 | 0 | 22,305
Patent acquisition cost | 0 | 0 | 0 | 1,610,066
Amortization of issuance costs and original issue debt discounts including beneficial conversion feature-part of interest expense | 0 | 3,620,092 | 5,069,446 | 19,754,169
Fair value of common stock and warrants issued to induce conversion of notes | 0 | 0 | 0 | 469,043
Costs of private placement convertible notes | 0 | 0 | 0 | 1,640,715
Change in fair value of derivative liability | 220,614 | 4,023,094 | (2,021,536) | 2,115,507
Gain on extinguishment of derivative liability | (3,441,752) | (2,445,095) | 0 | (5,886,847)
Amortization of deferred compensation | 0 | 0 | 0 | 3,060,744
Gain on disposition of assets | (41,923) |  |  | (27,497)
Depreciation and amortization | 15,399 | 36,077 | 34,717 | 546,375
Bad debt | 0 | 0 | 0 | 1,300
Changes in operating assets and liabilities: |  |  |  |
Accounts receivable | 0 | 0 | 0 | (1,380)
Prepaid expenses and other | 10,202 | 37,775 | (48,481) | (29,849)
Other assets | 4,500 | 0 | (2,310) | (5,830)
Accounts payable and accrued expenses | (43,408) | (192,796) | 415,519 | 4,791,646
Accounts payable - license agreements | (130,400) | 137,725 | (478,297) | (465,687)
Accounts payable and accrued expenses - related parties | 128,750 | (342,718) | (178,173) | (243,968)
Net cash used in operating activities | (5,912,368) | (4,517,585) | (4,723,952) | (38,632,070)
Cash flows from investing activities |  |  |  |
Purchase of equipment | (7,573) | (16,142) | (32,243) | (622,578)
Proceeds from sale of equipment | 27,000 | 0 | 0 | 44,478
Net cash used in investing activities | 19,427 | (16,142) | (32,243) | (578,099)
Cash flows from financing activities |  |  |  |
Net proceeds under equity line of credit | 0 | 0 | 0 | 1,262,386
(Decrease) increase in payables to related parties and stockholder | 0 | 0 | (86,947) | 536,979
Advances from founding executive officer | 0 | 0 | 0 | 517,208
Net proceeds from issuance of convertible notes and warrants | 0 | 1,835,840 | 5,360,070 | 18,400,888
Repayment of convertible notes | 0 | 0 | (14,276) | (296,397)
Net proceeds from sale of stock and exercise of warrants and options | 8,428,218 | 3,681,881 | 13,500 | 22,926,173
Net cash provided by financing activities | 8,428,218 | 5,517,721 | 5,272,347 | 43,347,237
Net increase in cash | 2,535,277 | 983,994 | 516,152 | 4,137,068
Cash, beginning of period | 1,601,791 | 617,797 | 101,645 | 0
Cash, end of period | 4,137,068 | 1,601,791 | 617,797 | 4,137,068
Supplemental disclosures of cash flow information |  |  |  |
Cash paid during the year for: Interest | 260 | 7,640 | 201 | 179,280
Cash paid during the year for: Income taxes | 0 | 800 | 0 | 8,282
Non-cash investing and financing activities |  |  |  |
Acquisition of intangible asset through advance from related party and issuance of common stock | 0 | 0 | 0 | 505,000
Deferred compensation for stock options issued for services | 0 | 0 | 0 | 3,202,931
Purchase of property and equipment financed by advance from related party | 0 | 0 | 0 | 3,550
Conversion of related party debt to equity | 0 | 0 | 0 | 515,000
Conversion of accounts payable and accrued expenses to common stock | 0 | 0 | 0 | 860,105
Cancellation of stock | 0 | 0 | 0 | 8,047
Conversion of accounts payable and accrued expenses to convertible debentures | 0 | 52,371 | 33,740 | 689,846
Conversion of related party debt to convertible debentures | 0 | 0 | 0 | 72,500
Conversion of convertible debentures to common stock | 0 | 3,789,634 | 2,425,711 | 19,540,985
Issuance of shares for settlement of loans and other payable to Morale/Matthews | 0 | 0 | 0 | 2,783,711
Write off of deferred compensation | 0 | 0 | 0 | 142,187
Fair value of derivative liability recorded as note discount | 0 | 0 | 0 | 2,130,625
Exercise of options applied to accounts payable | 49,000 | 0 | 0 | 116,500
Fair value of warrants issued to settle payables | 129,622 | 0 | 0 | 129,622
Receivable from sale of equipment | 27,000 | 0 | 0 | 27,000
Fair value of warrants and beneficial conversion feature associated with issued convertible notes | $ 0 | $ 1,888,211 | $ 2,305,311 | $ 15,800,944

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