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2. Summary of Significant Accounting Policies (Details Narrative) (USD $) | 3 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Dec. 31, 2014 | Sep. 30, 2014 | Jun. 30, 2014 | Mar. 31, 2014 | Dec. 31, 2013 | Sep. 30, 2013 | Jun. 30, 2013 | Mar. 31, 2013 | Dec. 31, 2014 | Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011
Net loss | $ (878,695)us-gaap_NetIncomeLoss | $ (715,774)us-gaap_NetIncomeLoss | $ (1,008,392)us-gaap_NetIncomeLoss | $ (1,403,474)us-gaap_NetIncomeLoss | $ (8,873,734)us-gaap_NetIncomeLoss | $ (1,445,125)us-gaap_NetIncomeLoss | $ (1,920,950)us-gaap_NetIncomeLoss | $ 1,582,800 us-gaap_NetIncomeLoss | $ (4,006,335)us-gaap_NetIncomeLoss | $ (10,657,009)us-gaap_NetIncomeLoss | $ (13,092,387)us-gaap_NetIncomeLoss |
Negative cash flow from operations |  |  |  |  |  |  |  |  | (3,527,695)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (5,912,368)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations | (4,517,585)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations |
Cash on Hand | 2,247,557 us-gaap_Cash |  |  |  | 4,137,068 us-gaap_Cash |  |  |  | 2,247,557 us-gaap_Cash | 4,137,068 us-gaap_Cash | 1,601,791 us-gaap_Cash | 617,797 us-gaap_Cash
Impairment on long-lived assets |  |  |  |  |  |  |  |  | 0 us-gaap_ImpairmentOfLongLivedAssetsHeldForUse | 0 us-gaap_ImpairmentOfLongLivedAssetsHeldForUse |  |
Research and development expenses |  |  |  |  |  |  |  |  | 893,452 us-gaap_ResearchAndDevelopmentExpense | 2,011,486 us-gaap_ResearchAndDevelopmentExpense | 963,184 us-gaap_ResearchAndDevelopmentExpense |
Patent costs |  |  |  |  |  |  |  |  | $ 103,434 us-gaap_LicenseCosts | $ 144,326 us-gaap_LicenseCosts | $ 104,150 us-gaap_LicenseCosts |
Options |  |  |  |  |  |  |  |  |  |  |  |
Antidilutive shares excluded from loss per share |  |  |  |  |  |  |  |  | 21,052,030 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_StockOptionMember | 20,309,908 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_StockOptionMember | 27,278,098 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_StockOptionMember |
Warrants |  |  |  |  |  |  |  |  |  |  |  |
Antidilutive shares excluded from loss per share |  |  |  |  |  |  |  |  | 5,692,087 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_WarrantMember | 11,763,966 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_WarrantMember | 42,205,507 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_WarrantMember |
Convertible Notes |  |  |  |  |  |  |  |  |  |  |  |
Antidilutive shares excluded from loss per share |  |  |  |  |  |  |  |  | 509,667 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_ConvertibleDebtMember | 0 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_ConvertibleDebtMember | 0 us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount / us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis = us-gaap_ConvertibleDebtMember |

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