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2. Summary of Significant Accounting Policies (Details) - shares
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Total shares that would have been anti-dilutive 35,439,898 27,153,599
Options [Member]    
Total shares that would have been anti-dilutive 23,184,256 21,761,512
Warrants [Member]    
Total shares that would have been anti-dilutive 8,885,242 5,392,087
Convertible Notes [Member]    
Total shares that would have been anti-dilutive 3,370,400 0