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        <link:usedOn>link:presentationLink</link:usedOn>

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        <link:usedOn>link:definitionLink</link:usedOn>

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        <link:usedOn>link:presentationLink</link:usedOn>

        <link:usedOn>link:definitionLink</link:usedOn>

        <link:usedOn>link:calculationLink</link:usedOn>
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        <link:definition>156 - Disclosure - Redeemable Common Stock and Stock Purchase Warrants (Details Textual)</link:definition>

        <link:usedOn>link:presentationLink</link:usedOn>

        <link:usedOn>link:definitionLink</link:usedOn>

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        <link:usedOn>link:definitionLink</link:usedOn>

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        <link:usedOn>link:definitionLink</link:usedOn>

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        <link:usedOn>link:definitionLink</link:usedOn>

        <link:usedOn>link:calculationLink</link:usedOn>
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      <link:roleType roleURI="http://championsoncology.com/role/SubsequentEventsDetailsTextual" id="SubsequentEventsDetailsTextual">
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        <link:usedOn>link:definitionLink</link:usedOn>

        <link:usedOn>link:calculationLink</link:usedOn>
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  <element name="BoardMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_BoardMember" />

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  <element name="LaboratoriesAndOfficeSpaceMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_LaboratoriesAndOfficeSpaceMember" />

  <element name="IsraelOfficeHeadquartersMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_IsraelOfficeHeadquartersMember" />

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  <element name="NewYorkLaboratoryMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_NewYorkLaboratoryMember" />

  <element name="CommitmentsAndContingenciesLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_CommitmentsAndContingenciesLineItems" />

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  <element name="SecondCompoundMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_SecondCompoundMember" />

  <element name="TevaAgreementLineItems" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_TevaAgreementLineItems" />

  <element name="PersonalizedOncologySolutionsMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_PersonalizedOncologySolutionsMember" />

  <element name="TranslationalOncologySolutionsMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_TranslationalOncologySolutionsMember" />

  <element name="UnallocatedCorporateOverheadMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_UnallocatedCorporateOverheadMember" />

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  <element name="PersonalizedOncologySolutions" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" xbrli:balance="credit" substitutionGroup="xbrli:item" id="csbr_PersonalizedOncologySolutions" />

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  <element name="MonthlyCapitalLeasePayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" xbrli:balance="debit" substitutionGroup="xbrli:item" id="csbr_MonthlyCapitalLeasePayment" />

  <element name="CapitalLeaseMinimumLeasePaymentPercentage" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_CapitalLeaseMinimumLeasePaymentPercentage" />

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  <element name="AggregateValueOfUnitsIssued" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" nillable="true" xbrli:balance="credit" substitutionGroup="xbrli:item" id="csbr_AggregateValueOfUnitsIssued" />

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  <element name="RepurchaseOfStockInPutOption" type="num:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_RepurchaseOfStockInPutOption" />

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  <element name="SecuritiesPurchaseAgreementMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_SecuritiesPurchaseAgreementMember" />

  <element name="AdditionalWarrantsIssuedToInvestors" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="csbr_AdditionalWarrantsIssuedToInvestors" />

  <element name="WarrantExercisePrice" type="num:perShareItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="csbr_WarrantExercisePrice" />

  <element name="SecuritiesPurchaseAgreementOneMember" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_SecuritiesPurchaseAgreementOneMember" />

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  <element name="RedeemableCommonStockAndStockPurchaseWarrantTextBlock" type="nonnum:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_RedeemableCommonStockAndStockPurchaseWarrantTextBlock" />

  <element name="ScheduleOfShareBasedPaymentAwardStockWarrantsValuationAssumptionsTableTextBlock" type="nonnum:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_ScheduleOfShareBasedPaymentAwardStockWarrantsValuationAssumptionsTableTextBlock" />

  <element name="PrivatePlacementTypeAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:dimensionItem" id="csbr_PrivatePlacementTypeAxis" />

  <element name="CommonStockPurchasePrice" type="num:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_CommonStockPurchasePrice" />

  <element name="ProceedsFromIssuanceOfCommonStockAndWarrants" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" xbrli:balance="debit" substitutionGroup="xbrli:item" id="csbr_ProceedsFromIssuanceOfCommonStockAndWarrants" />

  <element name="PrivatePlacementTypeDomain" type="nonnum:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_PrivatePlacementTypeDomain" />

  <element name="WarrantsExercisePricePerShare" type="num:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_WarrantsExercisePricePerShare" />

  <element name="PercentageOfCommonStockPurchased" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_PercentageOfCommonStockPurchased" />

  <element name="FederalIncomeTaxValuationAllowance" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" xbrli:balance="debit" substitutionGroup="xbrli:item" id="csbr_FederalIncomeTaxValuationAllowance" />

  <element name="StateAndLocalIncomeTaxValuationAllowance" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" xbrli:balance="debit" substitutionGroup="xbrli:item" id="csbr_StateAndLocalIncomeTaxValuationAllowance" />

  <element name="ForeignIncomeTaxValuationAllowance" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" xbrli:balance="debit" substitutionGroup="xbrli:item" id="csbr_ForeignIncomeTaxValuationAllowance" />

  <element name="ValuationAllowances" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" nillable="true" xbrli:balance="debit" substitutionGroup="xbrli:item" id="csbr_ValuationAllowances" />

  <element name="EffectiveIncomeTaxRateReconciliationPermanentDifferences" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_EffectiveIncomeTaxRateReconciliationPermanentDifferences" />

  <element name="DeferredTaxAssetsDeferredExpenseDepreciationAndAmortization" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" nillable="true" xbrli:balance="debit" substitutionGroup="xbrli:item" id="csbr_DeferredTaxAssetsDeferredExpenseDepreciationAndAmortization" />

  <element name="OperatingLossCarryForwardsExpirationYear" type="xbrli:stringItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_OperatingLossCarryForwardsExpirationYear" />

  <element name="SharebasedcompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantInPeriodWeightedAverageRemainingContractualTerms" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_SharebasedcompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantInPeriodWeightedAverageRemainingContractualTerms" />

  <element name="PercentageOfStrikePriceOnFairMarketValue" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_PercentageOfStrikePriceOnFairMarketValue" />

  <element name="StockOptionsAwardSharesToPurchaseUnregisteredCommonStock" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_StockOptionsAwardSharesToPurchaseUnregisteredCommonStock" />

  <element name="StockOptionsAwardSharesToPurchaseCommonStock" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_StockOptionsAwardSharesToPurchaseCommonStock" />

  <element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedPercentage" type="num:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="csbr_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsVestedPercentage" />
</schema>

