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v3.25.3

Condensed Consolidated Statements of Cash Flows $ in Thousands | 3 Months Ended | 9 Months Ended
--- | --- | ---
Sep. 30, 2025 USD ($) | Sep. 30, 2025 USD ($) | Sep. 30, 2024 USD ($)
CASH FLOWS FROM OPERATING ACTIVITIES: |  |  |
Net loss |  | $ (84,825) | $ (94,240)
Adjustments to reconcile net loss to cash flows from operating activities: |  |  |
Depreciation | $ 800 | 2,788 | 2,644
Impairment on lab equipment held-for-sale | 200 | 3,246 | 0
Write-off of prepaid expenses related to program terminations |  | 2,549 | 0
Share-based compensation expense |  | (499) | 4,419
Amortization of discount on marketable securities |  | (97) | (2,961)
Changes in assets and liabilities: |  |  |
Receivable from Former Parent |  | 51 | 4,155
Prepaid expenses |  | 3,915 | (5,999)
Other current assets |  | 891 | 36
Right-of-use assets |  | 3,649 | 4,114
Other assets |  | 10 | (27)
Accounts payable and accrued expenses |  | (13,800) | (3,591)
Operating lease liabilities |  | (4,475) | (5,463)
Other liabilities |  | (45) | 138
Cash flows used in operating activities |  | (86,642) | (96,775)
CASH FLOWS FROM INVESTING ACTIVITIES: |  |  |
Purchases of marketable securities |  | 0 | (167,475)
Sales and maturities of marketable securities |  | 29,000 | 106,000
Proceeds from sale of property and equipment |  | 780 | 0
Additions of property and equipment |  | (15) | (69)
Cash flows provided by (used in) investing activities |  | 29,765 | (61,544)
CASH FLOWS FROM FINANCING ACTIVITIES: |  |  |
Proceeds from issuance of ordinary shares under employee share plans |  | 28 | 196
Cash flows provided by financing activities |  | 28 | 196
Net decrease in cash, cash equivalents and restricted cash |  | (56,849) | (158,123)
Cash, cash equivalents and restricted cash-beginning of period |  | 117,431 | 271,110
Cash, cash equivalents and restricted cash-end of period | 60,582 | 60,582 | 112,987
RECONCILIATION OF BALANCE SHEET TO STATEMENT OF CASH FLOWS: |  |  |
Cash and cash equivalents | 58,871 | 58,871 | 111,018
Restricted cash, current | 1,711 | 1,711 | 0
Restricted cash, noncurrent | 0 | 0 | 1,969
Total cash, cash equivalents and restricted cash as shown in the statement of cash flows | $ 60,582 | $ 60,582 | $ 112,987

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