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Organization and Description of Business - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands | Aug. 20, 2025 | Apr. 14, 2025 | Nov. 15, 2023 | Nov. 14, 2023 | Sep. 30, 2025 | Dec. 31, 2024 | Sep. 30, 2024
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Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Cash and cash equivalents |  |  |  |  | $ 58,871 | $ 115,462 | $ 111,018
XOMA Royalty Corporation |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Base cash price per share | $ 2.035 |  |  |  |  |  |
Estimated closing net cash | $ 36,200 |  |  |  |  |  |
Maximum additional cash amount per share | $ 0.205 |  |  |  |  |  |
Discontinue of Clinical Development |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Percentage of positions reduced |  | 90.00% |  |  |  |  |
Alkermes |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |
Effective time of distribution |  |  |  | Nov. 15, 2023 |  |  |
Cash distribution received from parent |  |  |  | $ 275,000 |  |  |
Distribution term of shares |  |  | one ordinary share of the Company for every ten ordinary shares |  |  |  |

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