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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Operating expenses        
Research and development $ (4,288) $ 27,585 $ 46,414 $ 81,997
General and administrative 8,254 6,513 23,292 20,411
Restructuring and impairment     17,486  
Total operating expenses 3,966 34,098 87,192 102,408
Operating loss (3,966) (34,098) (87,192) (102,408)
Other income 260 2,339 2,367 8,168
Net loss (3,706) (31,759) (84,825) (94,240)
Other comprehensive (loss) gain:        
Unrealized (loss) gain on marketable securities   101 (20) 47
Other comprehensive (loss) gain   101 (20) 47
Comprehensive loss $ (3,706) $ (31,658) $ (84,845) $ (94,193)
Net loss per ordinary share - basic $ (0.21) $ (1.87) $ (4.92) $ (5.57)
Net loss per ordinary share - diluted $ (0.21) $ (1.87) $ (4.92) $ (5.57)
Weighted average ordinary shares outstanding - basic 17,321,544 17,028,552 17,254,516 16,916,096
Weighted average ordinary shares outstanding - diluted 17,321,544 17,028,552 17,254,516 16,916,096