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Condensed Consolidated Statements of Equity (Deficit) - USD ($)
$ in Thousands
Total
Ordinary Shares
Additional Paid in Capital
Accumulated Other Comprehensive (Loss)/Gain
Accumulated Deficit
Beginning balance at Dec. 31, 2023 $ 263,817 $ 167 $ 294,507   $ (30,857)
Beginning balance, in shares at Dec. 31, 2023   16,689,740      
Issuance of ordinary shares under employee share plans   $ 2 (2)    
Issuance of ordinary shares under employee share plans, shares   232,810      
Share-based compensation expense 2,101   2,101    
Unrealized gain (loss) on marketable securities (74)     $ (74)  
Net loss (30,917)       (30,917)
Ending balance at Mar. 31, 2024 234,927 $ 169 296,606 (74) (61,774)
Ending balance, in shares at Mar. 31, 2024   16,922,550      
Beginning balance at Dec. 31, 2023 263,817 $ 167 294,507   (30,857)
Beginning balance, in shares at Dec. 31, 2023   16,689,740      
Net loss (94,240)        
Ending balance at Sep. 30, 2024 174,141 $ 170 299,021 47 (125,097)
Ending balance, in shares at Sep. 30, 2024   17,038,950      
Beginning balance at Mar. 31, 2024 234,927 $ 169 296,606 (74) (61,774)
Beginning balance, in shares at Mar. 31, 2024   16,922,550      
Issuance of ordinary shares under employee share plans, shares   4,560      
Share-based compensation expense 1,190   1,190    
Unrealized gain (loss) on marketable securities 20     20  
Net loss (31,564)       (31,564)
Ending balance at Jun. 30, 2024 204,573 $ 169 297,796 (54) (93,338)
Ending balance, in shares at Jun. 30, 2024   16,927,110      
Issuance of ordinary shares under employee share plans 196 $ 1 195    
Issuance of ordinary shares under employee share plans, shares   111,840      
Share-based compensation expense 1,030   1,030    
Unrealized gain (loss) on marketable securities 101     101  
Net loss (31,759)       (31,759)
Ending balance at Sep. 30, 2024 174,141 $ 170 299,021 47 (125,097)
Ending balance, in shares at Sep. 30, 2024   17,038,950      
Beginning balance at Dec. 31, 2024 140,502 $ 171 299,682 20 (159,371)
Beginning balance, in shares at Dec. 31, 2024   17,095,371      
Issuance of ordinary shares under employee share plans 28 $ 2 26    
Issuance of ordinary shares under employee share plans, shares   169,446      
Share-based compensation expense 513   513    
Unrealized gain (loss) on marketable securities (19)     (19)  
Net loss (33,137)       (33,137)
Ending balance at Mar. 31, 2025 107,887 $ 173 300,221 1 (192,508)
Ending balance, in shares at Mar. 31, 2025   17,264,817      
Beginning balance at Dec. 31, 2024 140,502 $ 171 299,682 20 (159,371)
Beginning balance, in shares at Dec. 31, 2024   17,095,371      
Net loss (84,825)        
Ending balance at Sep. 30, 2025 55,186 $ 174 299,208   (244,196)
Ending balance, in shares at Sep. 30, 2025   17,324,771      
Beginning balance at Mar. 31, 2025 107,887 $ 173 300,221 1 (192,508)
Beginning balance, in shares at Mar. 31, 2025   17,264,817      
Issuance of ordinary shares under employee share plans, shares   9,720      
Share-based compensation expense (1,121)   (1,121)    
Unrealized gain (loss) on marketable securities (1)     $ (1)  
Net loss (47,982)       (47,982)
Ending balance at Jun. 30, 2025 58,783 $ 173 299,100   (240,490)
Ending balance, in shares at Jun. 30, 2025   17,274,537      
Issuance of ordinary shares under employee share plans   $ 1 (1)    
Issuance of ordinary shares under employee share plans, shares   50,234      
Share-based compensation expense 109   109    
Net loss (3,706)       (3,706)
Ending balance at Sep. 30, 2025 $ 55,186 $ 174 $ 299,208   $ (244,196)
Ending balance, in shares at Sep. 30, 2025   17,324,771