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Restructuring - Additional Information (Details) $ in Thousands			3 Months Ended	9 Months Ended
	Jun. 03, 2025 USD ($)	Apr. 14, 2025 USD ($) Positions	Sep. 30, 2025 USD ($)	Sep. 30, 2025 USD ($)	Sep. 30, 2024 USD ($)
Restructuring Cost and Reserve [Line Items]
Restructuring Charges				$ 11,938
Impairment on lab equipment held-for-sale			$ 200	3,246	$ 0
Write-offs prepayments for services related to our clinical and pre-clinical programs				2,500
Contract Termination Costs
Restructuring Cost and Reserve [Line Items]
Restructuring Charges	$ 2,500			$ 2,481
Discontinue of Clinical Development
Restructuring Cost and Reserve [Line Items]
Number of positions reduced | Positions		104
Percentage of positions reduced		90.00%
Discontinue of Clinical Development | Severance Payments and Employee Benefit Costs
Restructuring Cost and Reserve [Line Items]
Restructuring expected cost		$ 9,500

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