    <SEC-DOCUMENT>0000950170-25-058967-index.html : 20250428
    <SEC-HEADER>0000950170-25-058967.hdr.sgml : 20250428
    <ACCEPTANCE-DATETIME>20250428080303
    ACCESSION NUMBER:		0000950170-25-058967
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		3
    FILED AS OF DATE:		20250428
    DATE AS OF CHANGE:		20250428

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Mural Oncology plc
    		CENTRAL INDEX KEY:			0001971543
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				000000000
    		STATE OF INCORPORATION:			L2
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-41837
    		FILM NUMBER:		25876002

    	BUSINESS ADDRESS:
    		STREET 1:		10 EARLSFORT TERRACE
    		CITY:			DUBLIN 2
    		STATE:			L2
    		ZIP:			D02 T380
    		BUSINESS PHONE:		353 1 905 8020

    	MAIL ADDRESS:
    		STREET 1:		10 EARLSFORT TERRACE
    		CITY:			DUBLIN 2
    		STATE:			L2
    		ZIP:			D02 T380

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Mural Oncology Ltd
    		DATE OF NAME CHANGE:	20230403

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	Pistachiovale Ltd
    		DATE OF NAME CHANGE:	20230329
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEFA14A
    <SEQUENCE>1
    <FILENAME>copy_of_mura-defa14a-202.htm
    <DESCRIPTION>DEFA14A
    <TEXT>
    Document 1 - file: copy_of_mura-defa14a-202.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>img86461489_0.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 2 - file: img86461489_0.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>img86461489_1.jpg
    <DESCRIPTION>GRAPHIC
    <TEXT>
    Document 3 - file: img86461489_1.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>