<?xml version="1.0"?>
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:gen="http://xbrl.org/2008/generic" xmlns:ref="http://www.xbrl.org/2006/ref" xmlns:label="http://xbrl.org/2008/label" xmlns:xbrldt="http://xbrl.org/2005/xbrldt">
  <link:arcroleRef arcroleURI="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" xlink:href="http://www.xbrl.org/lrr/arcrole/esma-arcrole-2018-11-21.xsd#wider-narrower" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension" xlink:type="simple" />
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default" xlink:type="simple" />
  <link:roleRef roleURI="https://www.esma.europa.eu/xbrl/role/cor/esef_role-999999" xlink:type="simple" xlink:href="https://www.esma.europa.eu/taxonomy/2022-03-24/esef_cor.xsd#esef_role-999999" />
  <link:roleRef roleURI="https://www.esma.europa.eu/xbrl/role/all/ias_1_role-610000" xlink:type="simple" xlink:href="neurones-2024-12-31.xsd#ias_1_role-610000" />
  <link:roleRef roleURI="http://www.esef_all.com/role/Anchoring" xlink:type="simple" xlink:href="neurones-2024-12-31.xsd#Anchoring" />
  <link:definitionLink xlink:role="https://www.esma.europa.eu/xbrl/role/cor/esef_role-999999" xlink:type="extended">
    <link:loc xlink:label="LineItemsNotDimensionallyQualified" xlink:href="https://www.esma.europa.eu/taxonomy/2022-03-24/esef_cor.xsd#esef_cor_LineItemsNotDimensionallyQualified" xlink:type="locator" />
    <link:loc xlink:label="loc_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AddressOfRegisteredOfficeOfEntity" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_1" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_2" xlink:href="neurones-2024-12-31.xsd#neurones_AdjustmentsForCapitalLossesCapitalGainsOnSaleNetOfTax" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_2" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_3" xlink:href="neurones-2024-12-31.xsd#neurones_AdjustmentsForDepreciationOfRightsOfUse" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_3" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_4" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForFairValueGainsLosses" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_4" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_5" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForFinanceIncomeCost" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_5" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_6" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForGainLossOnDisposalOfInvestmentsInSubsidiariesJointVenturesAndAssociates" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_6" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_7" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForIncomeTaxExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_7" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_8" xlink:href="neurones-2024-12-31.xsd#neurones_AdjustmentsForLossesGainsOnRightsOfUse" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_8" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_9" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForSharebasedPayments" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_9" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_10" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Assets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_10" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_11" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_BasicEarningsLossPerShare" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_11" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_12" xlink:href="neurones-2024-12-31.xsd#neurones_CapitalReduction" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_12" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_13" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashAndCashEquivalents" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_13" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_14" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashAndCashEquivalentsIfDifferentFromStatementOfFinancialPosition" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_14" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_15" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromLosingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_15" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_16" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_16" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_17" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_17" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_18" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperatingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_18" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_19" xlink:href="neurones-2024-12-31.xsd#neurones_CashFlowsFromUsedInOperationsAfterCostOfNetDebtAndIncomeTaxExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_19" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_20" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInOperationsBeforeChangesInWorkingCapital" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_20" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_21" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsUsedInObtainingControlOfSubsidiariesOrOtherBusinessesClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_21" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_22" xlink:href="neurones-2024-12-31.xsd#neurones_ChangesAndErrorToIAS8" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_22" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_23" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ComprehensiveIncome" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_23" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_24" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ComprehensiveIncomeAttributableToNoncontrollingInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_24" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_25" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ComprehensiveIncomeAttributableToOwnersOfParent" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_25" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_26" xlink:href="neurones-2024-12-31.xsd#neurones_ConsolidatedReservesIncludingNetIncome" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_26" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_27" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CountryOfIncorporation" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_27" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_28" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_28" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_29" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentLeaseLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_29" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_30" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_30" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_31" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentProvisions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_31" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_32" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentTaxAssetsCurrent" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_32" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_33" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CurrentTaxLiabilitiesCurrent" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_33" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_34" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DeferredTaxAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_34" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_35" xlink:href="neurones-2024-12-31.xsd#neurones_DepreciationAndAmortisationExpenseExceptRightsOfUse" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_35" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_36" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DepreciationRightofuseAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_36" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_37" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForBusinessCombinationsAndGoodwillExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_37" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_38" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForBusinessCombinationsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_38" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_39" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForDeferredIncomeTaxExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_39" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_40" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForDepreciationExpenseExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_40" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_41" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForEarningsPerShareExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_41" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_42" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForEmployeeBenefitsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_42" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_43" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForFinancialAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_43" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_44" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForFinancialInstrumentsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_44" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_45" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForFinancialLiabilitiesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_45" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_46" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForGoodwillExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_46" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_47" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForImpairmentOfAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_47" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_48" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForImpairmentOfFinancialAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_48" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_49" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForImpairmentOfNonfinancialAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_49" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_50" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForIncomeTaxExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_50" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_51" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForIntangibleAssetsAndGoodwillExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_51" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_52" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForIntangibleAssetsOtherThanGoodwillExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_52" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_53" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForLeasesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_53" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_54" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForMeasuringInventories" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_54" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_55" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForPropertyPlantAndEquipmentExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_55" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_56" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForProvisionsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_56" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_57" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForRecognitionOfRevenue" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_57" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_58" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForSegmentReportingExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_58" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_59" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForSharebasedPaymentTransactionsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_59" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_60" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForSubsidiariesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_60" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_61" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForTradeAndOtherPayablesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_61" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_62" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForTradeAndOtherReceivablesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_62" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_63" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForTransactionsWithNoncontrollingInterestsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_63" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_64" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyForTreasurySharesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_64" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_65" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfAccountingPolicyToDetermineComponentsOfCashAndCashEquivalents" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_65" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_66" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DescriptionOfNatureOfEntitysOperationsAndPrincipalActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_66" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_67" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DilutedEarningsLossPerShare" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_67" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_68" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfAccountingJudgementsAndEstimatesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_68" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_69" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfAllowanceForCreditLossesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_69" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_70" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfAuditorsRemunerationExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_70" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_71" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfAuthorisationOfFinancialStatementsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_71" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_72" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfBasisOfConsolidationExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_72" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_73" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfBasisOfPreparationOfFinancialStatementsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_73" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_74" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfBorrowingsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_74" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_75" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfBusinessCombinationsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_75" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_76" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfCashAndCashEquivalentsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_76" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_77" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfCashFlowStatementExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_77" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_78" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfChangesInAccountingPoliciesAccountingEstimatesAndErrorsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_78" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_79" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfChangesInAccountingPoliciesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_79" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_80" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfCommitmentsAndContingentLiabilitiesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_80" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_81" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfCommitmentsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_81" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_82" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfCompositionOfGroupExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_82" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_83" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfCreditRiskExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_83" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_84" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfDeferredIncomeExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_84" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_85" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfDeferredTaxesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_85" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_86" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfDepreciationAndAmortisationExpenseExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_86" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_87" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfDividendsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_87" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_88" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfEarningsPerShareExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_88" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_89" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfEmployeeBenefitsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_89" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_90" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfEntitysReportableSegmentsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_90" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_91" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfEventsAfterReportingPeriodExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_91" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_92" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfExpensesByNatureExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_92" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_93" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFairValueMeasurementExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_93" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_94" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFairValueOfFinancialInstrumentsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_94" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_95" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFinanceCostExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_95" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_96" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFinanceIncomeExpenseExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_96" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_97" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFinanceIncomeExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_97" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_98" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFinancialAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_98" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_99" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFinancialInstrumentsAtFairValueThroughProfitOrLossExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_99" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_100" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFinancialInstrumentsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_100" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_101" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfFinancialRiskManagementExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_101" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_102" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfGeneralInformationAboutFinancialStatementsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_102" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_103" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfGoodwillExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_103" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_104" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfGovernmentGrantsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_104" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_105" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfImpairmentOfAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_105" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_106" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfIncomeTaxExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_106" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_107" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInformationAboutEmployeesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_107" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_108" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInformationAboutKeyManagementPersonnelExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_108" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_109" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfIntangibleAssetsAndGoodwillExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_109" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_110" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfIntangibleAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_110" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_111" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInterestExpenseExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_111" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_112" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInterestIncomeExpenseExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_112" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_113" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInterestIncomeExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_113" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_114" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInterestsInOtherEntitiesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_114" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_115" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInventoriesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_115" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_116" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfInvestmentsOtherThanInvestmentsAccountedForUsingEquityMethodExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_116" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_117" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfIssuedCapitalExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_117" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_118" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfLeasesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_118" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_119" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfLiquidityRiskExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_119" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_120" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfMarketRiskExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_120" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_121" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfMaterialAccountingPolicyInformationExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_121" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_122" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfNoncontrollingInterestsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_122" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_123" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfObjectivesPoliciesAndProcessesForManagingCapitalExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_123" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_124" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfOtherLiabilitiesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_124" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_125" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfOtherNoncurrentLiabilitiesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_125" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_126" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfOtherOperatingExpenseExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_126" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_127" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfOtherOperatingIncomeExpenseExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_127" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_128" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfOtherOperatingIncomeExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_128" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_129" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfOtherProvisionsContingentLiabilitiesAndContingentAssetsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_129" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_130" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfPropertyPlantAndEquipmentExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_130" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_131" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfProvisionsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_131" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_132" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfRelatedPartyExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_132" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_133" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfRevenueExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_133" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_134" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfRevenueFromContractsWithCustomersExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_134" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_135" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfSharebasedPaymentArrangementsExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_135" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_136" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfShareCapitalReservesAndOtherEquityInterestExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_136" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_137" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfSignificantInvestmentsInSubsidiariesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_137" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_138" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfTradeAndOtherPayablesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_138" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_139" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfTradeAndOtherReceivablesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_139" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_140" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfTransactionsBetweenRelatedPartiesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_140" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_141" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DisclosureOfTreasurySharesExplanatory" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_141" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_142" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DividendsPaid" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_142" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_143" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DividendsPaidToEquityHoldersOfParentClassifiedAsFinancingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_143" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_144" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DividendsPaidToNoncontrollingInterestsClassifiedAsFinancingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_144" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_145" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DividendsProposedOrDeclaredBeforeFinancialStatementsAuthorisedForIssueButNotRecognisedAsDistributionToOwnersPerShare" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_145" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_146" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DividendsRecognisedAsDistributionsToNoncontrollingInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_146" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_147" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EffectOfExchangeRateChangesOnCashAndCashEquivalents" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_147" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_148" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EmployeeBenefitsExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_148" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_149" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Equity" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_149" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_150" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityAndLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_150" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_151" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityAttributableToOwnersOfParent" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_151" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_152" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_FinanceIncome" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_152" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_153" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_FinanceIncomeCost" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_153" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_154" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncomeTaxesPaidRefundClassifiedAsOperatingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_154" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_155" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncomeTaxExpenseContinuingOperations" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_155" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_156" xlink:href="neurones-2024-12-31.xsd#neurones_IncreaseDecreaseInCapital" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_156" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_157" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseInCashAndCashEquivalentsBeforeEffectOfExchangeRateChanges" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_157" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_158" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseInWorkingCapital" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_158" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_159" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughAppropriationOfRetainedEarnings" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_159" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_160" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughChangeInEquityOfSubsidiaries" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_160" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_161" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_161" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_162" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughTransactionsWithOwners" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_162" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_163" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughTreasuryShareTransactions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_163" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_164" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IntangibleAssetsAndGoodwill" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_164" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_165" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_InterestExpenseOnLeaseLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_165" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_166" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Inventories" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_166" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_167" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IssuedCapital" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_167" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_168" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_LegalFormOfEntity" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_168" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_169" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NameOfParentEntity" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_169" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_170" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NameOfReportingEntityOrOtherMeansOfIdentification" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_170" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_171" xlink:href="neurones-2024-12-31.xsd#neurones_NetAllocationsToDepreciationAndProvisions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_171" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_172" xlink:href="neurones-2024-12-31.xsd#neurones_NetFinancialInterest" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_172" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_173" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncontrollingInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_173" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_174" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_174" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_175" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentFinancialAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_175" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_176" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentLeaseLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_176" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_177" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_177" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_178" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncurrentProvisions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_178" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_179" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_179" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_180" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_180" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_181" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherCurrentFinancialLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_181" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_182" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherFinanceCost" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_182" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_183" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherNoncurrentFinancialLiabilities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_183" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_184" xlink:href="neurones-2024-12-31.xsd#neurones_OtherOperatingExpensesFromOrdinaryActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_184" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_185" xlink:href="neurones-2024-12-31.xsd#neurones_OtherOperatingIncomeFromOrdinaryActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_185" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_186" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PaymentsFromChangesInOwnershipInterestsInSubsidiaries" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_186" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_187" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PaymentsOfLeaseLiabilitiesClassifiedAsFinancingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_187" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_188" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PrincipalPlaceOfBusiness" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_188" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_189" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromBorrowingsClassifiedAsFinancingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_189" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_190" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromContributionsOfNoncontrollingInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_190" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_191" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromSalesOrMaturityOfFinancialInstrumentsClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_191" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_192" xlink:href="neurones-2024-12-31.xsd#neurones_ProceedsOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_192" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_193" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLoss" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_193" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_194" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossAttributableToNoncontrollingInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_194" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_195" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossAttributableToOwnersOfParent" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_195" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_196" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossBeforeTax" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_196" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_197" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossFromContinuingOperations" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_197" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_198" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossFromOperatingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_198" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_199" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PropertyPlantAndEquipment" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_199" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_200" xlink:href="neurones-2024-12-31.xsd#neurones_ProvisionExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_200" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_201" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PurchaseOfFinancialInstrumentsClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_201" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_202" xlink:href="neurones-2024-12-31.xsd#neurones_PurchaseOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_202" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_203" xlink:href="neurones-2024-12-31.xsd#neurones_PurchaseOrProceedsFromSalesOfTreasuryShares" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_203" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_204" xlink:href="neurones-2024-12-31.xsd#neurones_PutOptionOnMinorityInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_204" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_205" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RawMaterialsAndConsumablesUsed" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_205" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_206" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RepaymentsOfBorrowingsClassifiedAsFinancingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_206" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_207" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RevenueFromContractsWithCustomers" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_207" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_208" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RevenueFromRenderingOfServices" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_208" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_209" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RevenueFromSaleOfGoods" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_209" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_210" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RightofuseAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_210" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_211" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ServicesExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_211" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_212" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_SharePremium" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_212" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_213" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_StatementOfIFRSCompliance" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_213" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_214" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_TaxExpenseOtherThanIncomeTaxExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_214" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_215" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_TradeAndOtherCurrentPayables" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_215" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_216" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_TradeAndOtherCurrentReceivables" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1.0" xlink:from="loc_216" xlink:to="LineItemsNotDimensionallyQualified" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
  </link:definitionLink>
  <link:definitionLink xlink:role="http://www.esef_all.com/role/Anchoring" xlink:type="extended">
    <link:loc xlink:label="loc_choring_1_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsToReconcileProfitLossOtherThanChangesInWorkingCapital" xlink:type="locator" />
    <link:loc xlink:label="neurones_NetAllocationsToDepreciationAndProvisions" xlink:href="neurones-2024-12-31.xsd#neurones_NetAllocationsToDepreciationAndProvisions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_1_1" xlink:to="neurones_NetAllocationsToDepreciationAndProvisions" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_4_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ExpenseByNature" xlink:type="locator" />
    <link:loc xlink:label="neurones_OtherOperatingExpensesFromOrdinaryActivities" xlink:href="neurones-2024-12-31.xsd#neurones_OtherOperatingExpensesFromOrdinaryActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_4_1" xlink:to="neurones_OtherOperatingExpensesFromOrdinaryActivities" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_5_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForLossesGainsOnDisposalOfNoncurrentAssets" xlink:type="locator" />
    <link:loc xlink:label="neurones_AdjustmentsForCapitalLossesCapitalGainsOnSaleNetOfTax" xlink:href="neurones-2024-12-31.xsd#neurones_AdjustmentsForCapitalLossesCapitalGainsOnSaleNetOfTax" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_5_1" xlink:to="neurones_AdjustmentsForCapitalLossesCapitalGainsOnSaleNetOfTax" xlink:type="arc" />
    <link:loc xlink:label="neurones_AdjustmentsForLossesGainsOnRightsOfUse" xlink:href="neurones-2024-12-31.xsd#neurones_AdjustmentsForLossesGainsOnRightsOfUse" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_5_1" xlink:to="neurones_AdjustmentsForLossesGainsOnRightsOfUse" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_7_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromDisposalsOfPropertyPlantAndEquipmentIntangibleAssetsOtherThanGoodwillInvestmentPropertyAndOtherNoncurrentAssets" xlink:type="locator" />
    <link:loc xlink:label="neurones_ProceedsOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:href="neurones-2024-12-31.xsd#neurones_ProceedsOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_7_1" xlink:to="neurones_ProceedsOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_10_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLossFromOperatingActivities" xlink:type="locator" />
    <link:loc xlink:label="neurones_ProvisionExpense" xlink:href="neurones-2024-12-31.xsd#neurones_ProvisionExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_10_1" xlink:to="neurones_ProvisionExpense" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_11_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_CashFlowsFromUsedInFinancingActivities" xlink:type="locator" />
    <link:loc xlink:label="neurones_CapitalReduction" xlink:href="neurones-2024-12-31.xsd#neurones_CapitalReduction" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_11_1" xlink:to="neurones_CapitalReduction" xlink:type="arc" />
    <link:loc xlink:label="neurones_NetFinancialInterest" xlink:href="neurones-2024-12-31.xsd#neurones_NetFinancialInterest" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_11_1" xlink:to="neurones_NetFinancialInterest" xlink:type="arc" />
    <link:loc xlink:label="neurones_PurchaseOrProceedsFromSalesOfTreasuryShares" xlink:href="neurones-2024-12-31.xsd#neurones_PurchaseOrProceedsFromSalesOfTreasuryShares" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_11_1" xlink:to="neurones_PurchaseOrProceedsFromSalesOfTreasuryShares" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_16_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForDepreciationExpense" xlink:type="locator" />
    <link:loc xlink:label="neurones_AdjustmentsForDepreciationOfRightsOfUse" xlink:href="neurones-2024-12-31.xsd#neurones_AdjustmentsForDepreciationOfRightsOfUse" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_16_1" xlink:to="neurones_AdjustmentsForDepreciationOfRightsOfUse" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_17_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughChangesInOwnershipInterestsInSubsidiariesThatDoNotResultInLossOfControl" xlink:type="locator" />
    <link:loc xlink:label="neurones_PutOptionOnMinorityInterests" xlink:href="neurones-2024-12-31.xsd#neurones_PutOptionOnMinorityInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_17_1" xlink:to="neurones_PutOptionOnMinorityInterests" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_19_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DepreciationAndAmortisationExpense" xlink:type="locator" />
    <link:loc xlink:label="neurones_DepreciationAndAmortisationExpenseExceptRightsOfUse" xlink:href="neurones-2024-12-31.xsd#neurones_DepreciationAndAmortisationExpenseExceptRightsOfUse" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_19_1" xlink:to="neurones_DepreciationAndAmortisationExpenseExceptRightsOfUse" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_23_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityAttributableToOwnersOfParent" xlink:type="locator" />
    <link:loc xlink:label="neurones_ConsolidatedReservesIncludingNetIncome" xlink:href="neurones-2024-12-31.xsd#neurones_ConsolidatedReservesIncludingNetIncome" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_23_1" xlink:to="neurones_ConsolidatedReservesIncludingNetIncome" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_24_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughTransactionsWithOwners" xlink:type="locator" />
    <link:loc xlink:label="neurones_IncreaseDecreaseInCapital" xlink:href="neurones-2024-12-31.xsd#neurones_IncreaseDecreaseInCapital" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_24_1" xlink:to="neurones_IncreaseDecreaseInCapital" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_26_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherIncome" xlink:type="locator" />
    <link:loc xlink:label="neurones_OtherOperatingIncomeFromOrdinaryActivities" xlink:href="neurones-2024-12-31.xsd#neurones_OtherOperatingIncomeFromOrdinaryActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_26_1" xlink:to="neurones_OtherOperatingIncomeFromOrdinaryActivities" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_27_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PurchaseOfPropertyPlantAndEquipmentIntangibleAssetsOtherThanGoodwillInvestmentPropertyAndOtherNoncurrentAssets" xlink:type="locator" />
    <link:loc xlink:label="neurones_PurchaseOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:href="neurones-2024-12-31.xsd#neurones_PurchaseOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_27_1" xlink:to="neurones_PurchaseOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_28_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ChangesInEquity" xlink:type="locator" />
    <link:loc xlink:label="neurones_ChangesAndErrorToIAS8" xlink:href="neurones-2024-12-31.xsd#neurones_ChangesAndErrorToIAS8" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="loc_choring_28_1" xlink:to="neurones_ChangesAndErrorToIAS8" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_22_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AccumulatedOtherComprehensiveIncome" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_ConsolidatedReservesIncludingNetIncome" xlink:to="loc_choring_22_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_25_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RetainedEarnings" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_ConsolidatedReservesIncludingNetIncome" xlink:to="loc_choring_25_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_31_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_TreasuryShares" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_ConsolidatedReservesIncludingNetIncome" xlink:to="loc_choring_31_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_6_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DepreciationPropertyPlantAndEquipment" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_DepreciationAndAmortisationExpenseExceptRightsOfUse" xlink:to="loc_choring_6_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_20_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AmortisationExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_DepreciationAndAmortisationExpenseExceptRightsOfUse" xlink:to="loc_choring_20_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_2_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ReductionOfIssuedCapital" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_IncreaseDecreaseInCapital" xlink:to="loc_choring_2_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_9_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IssueOfEquity" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_IncreaseDecreaseInCapital" xlink:to="loc_choring_9_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_14_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForProvisions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_NetAllocationsToDepreciationAndProvisions" xlink:to="loc_choring_14_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_30_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AdjustmentsForAmortisationExpense" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_NetAllocationsToDepreciationAndProvisions" xlink:to="loc_choring_30_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_29_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_InterestPaidClassifiedAsFinancingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_NetFinancialInterest" xlink:to="loc_choring_29_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_12_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_LossesOnDisposalsOfNoncurrentAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_OtherOperatingExpensesFromOrdinaryActivities" xlink:to="loc_choring_12_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_15_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_GainsOnDisposalsOfNoncurrentAssets" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_OtherOperatingIncomeFromOrdinaryActivities" xlink:to="loc_choring_15_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_3_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromSalesOfIntangibleAssetsClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_ProceedsOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:to="loc_choring_3_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_13_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromSalesOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_ProceedsOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:to="loc_choring_13_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_8_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PurchaseOfIntangibleAssetsClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_PurchaseOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:to="loc_choring_8_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_21_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PurchaseOfPropertyPlantAndEquipmentClassifiedAsInvestingActivities" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_PurchaseOfPropertyPlantEquipmentAndIntangibleAssetsOtherThanGoodwill" xlink:to="loc_choring_21_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_18_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_PaymentsToAcquireOrRedeemEntitysShares" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_PurchaseOrProceedsFromSalesOfTreasuryShares" xlink:to="loc_choring_18_1" xlink:type="arc" />
    <link:loc xlink:label="loc_choring_32_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProceedsFromSaleOrIssueOfTreasuryShares" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://www.esma.europa.eu/xbrl/esef/arcrole/wider-narrower" order="1" xlink:from="neurones_PurchaseOrProceedsFromSalesOfTreasuryShares" xlink:to="loc_choring_32_1" xlink:type="arc" />
  </link:definitionLink>
  <link:definitionLink xlink:role="https://www.esma.europa.eu/xbrl/role/all/ias_1_role-610000" xlink:type="extended">
    <link:loc xlink:label="loc_-610000_1_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityAttributableToOwnersOfParentMember" xlink:type="locator" />
    <link:loc xlink:label="loc_-610000_2_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_SharePremiumMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_1_1" xlink:to="loc_-610000_2_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_4_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ReserveOfSharebasedPaymentsMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_1_1" xlink:to="loc_-610000_4_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_6_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IssuedCapitalMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_1_1" xlink:to="loc_-610000_6_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_8_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RetainedEarningsProfitLossForReportingPeriodMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_1_1" xlink:to="loc_-610000_8_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_9_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_TreasurySharesMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_1_1" xlink:to="loc_-610000_9_1" xlink:type="arc" />
    <link:loc xlink:label="neurones_ConsolidatedReservesMember" xlink:href="neurones-2024-12-31.xsd#neurones_ConsolidatedReservesMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_1_1" xlink:to="neurones_ConsolidatedReservesMember" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_7_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityMember" xlink:type="locator" />
    <link:loc xlink:label="loc_-610000_1_12" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityAttributableToOwnersOfParentMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_7_1" xlink:to="loc_-610000_1_12" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_10_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_NoncontrollingInterestsMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_7_1" xlink:to="loc_-610000_10_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_11_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ReserveOfExchangeDifferencesOnTranslationMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_7_1" xlink:to="loc_-610000_11_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_13_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_StatementOfChangesInEquityAbstract" xlink:type="locator" />
    <link:loc xlink:label="loc_-610000_19_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_StatementOfChangesInEquityLineItems" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_13_1" xlink:to="loc_-610000_19_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_27_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_StatementOfChangesInEquityTable" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" order="1" xlink:from="loc_-610000_13_1" xlink:to="loc_-610000_27_1" xlink:type="arc" xbrldt:contextElement="scenario" xbrldt:closed="true" />
    <link:loc xlink:label="loc_-610000_12_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughChangeInEquityOfSubsidiaries" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_12_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_14_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughAppropriationOfRetainedEarnings" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_14_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_15_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_Equity" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_15_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_16_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxGainsLossesOnRemeasurementsOfDefinedBenefitPlans" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_16_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_17_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DividendsPaid" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_17_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_18_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ComprehensiveIncome" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_18_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_20_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughTransactionsWithOwners" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_20_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_21_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ProfitLoss" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_21_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_22_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_DividendsRecognisedAsDistributionsToNoncontrollingInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_22_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_23_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughSharebasedPaymentTransactions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_23_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_24_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_OtherComprehensiveIncomeNetOfTaxExchangeDifferencesOnTranslation" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_24_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_25_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_IncreaseDecreaseThroughTreasuryShareTransactions" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="loc_-610000_25_1" xlink:type="arc" />
    <link:loc xlink:label="neurones_ChangesAndErrorToIAS8" xlink:href="neurones-2024-12-31.xsd#neurones_ChangesAndErrorToIAS8" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="neurones_ChangesAndErrorToIAS8" xlink:type="arc" />
    <link:loc xlink:label="neurones_IncreaseDecreaseInCapital" xlink:href="neurones-2024-12-31.xsd#neurones_IncreaseDecreaseInCapital" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="neurones_IncreaseDecreaseInCapital" xlink:type="arc" />
    <link:loc xlink:label="neurones_PutOptionOnMinorityInterests" xlink:href="neurones-2024-12-31.xsd#neurones_PutOptionOnMinorityInterests" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="loc_-610000_19_1" xlink:to="neurones_PutOptionOnMinorityInterests" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_26_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ComponentsOfEquityAxis" xlink:type="locator" />
    <link:loc xlink:label="loc_-610000_7_12" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_EquityMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" order="1" xlink:from="loc_-610000_26_1" xlink:to="loc_-610000_7_12" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_26_12" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_ComponentsOfEquityAxis" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" order="1" xlink:from="loc_-610000_27_1" xlink:to="loc_-610000_26_12" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_3_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_AccumulatedOtherComprehensiveIncomeMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="neurones_ConsolidatedReservesMember" xlink:to="loc_-610000_3_1" xlink:type="arc" />
    <link:loc xlink:label="loc_-610000_5_1" xlink:href="https://xbrl.ifrs.org/taxonomy/2022-03-24/full_ifrs/full_ifrs-cor_2022-03-24.xsd#ifrs-full_RetainedEarningsExcludingProfitLossForReportingPeriodMember" xlink:type="locator" />
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" order="1" xlink:from="neurones_ConsolidatedReservesMember" xlink:to="loc_-610000_5_1" xlink:type="arc" />
  </link:definitionLink>
</link:linkbase>