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Property, plant and equipment - Summary of Property, Plant and Equipment Leased (Details) € in Millions | 1 Months Ended | 12 Months Ended |
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Dec. 31, 2018 lease | Dec. 31, 2022 EUR (€) | Dec. 31, 2021 EUR (€) | Dec. 31, 2020 EUR (€) | Dec. 31, 2019 EUR (€)
Disclosure of detailed information about property, plant and equipment [line items] |  |  |  |  |  |  |
Right-of-use assets at beginning of period |  | € 1,948 | € 1,198 | [1] |  |  |
Right-of-use assets at end of period |  | 1,815 | 1,948 |  | € 1,198 | [1] |
Right-of-use assets |  | € 1,815 | 1,948 |  | 1,198 | [1] |
Lease liabilities |  |  | 2,181 |  | 2,108 |  | € 1,163
Cambridge, Massachusetts |  |  |  |  |  |  |
Disclosure of detailed information about property, plant and equipment [line items] |  |  |  |  |  |  |
Number of lease agreements signed | lease | 2 |  |  |  |  |  |
Initial lease term | 15 years | 15 years |  |  |  |  |
Office space, Cambridge, Massachusetts |  |  |  |  |  |  |
Disclosure of detailed information about property, plant and equipment [line items] |  |  |  |  |  |  |
Right-of-use assets at beginning of period |  | € 320 |  |  |  |  |
Right-of-use assets at end of period |  |  | 320 |  |  |  |
Right-of-use assets |  |  | 320 |  |  |  |
Lease liabilities |  |  | 320 |  |  |  |
Laboratory facilities, Cambridge, Massachusetts |  |  |  |  |  |  |
Disclosure of detailed information about property, plant and equipment [line items] |  |  |  |  |  |  |
Right-of-use assets at beginning of period |  | 424 |  |  |  |  |
Right-of-use assets at end of period |  |  | 424 |  |  |  |
Right-of-use assets |  |  | 424 |  |  |  |
Lease liabilities |  |  | 424 |  |  |  |
Gross value |  |  |  |  |  |  |
Disclosure of detailed information about property, plant and equipment [line items] |  |  |  |  |  |  |
Right-of-use assets at beginning of period |  | 2,745 | 1,711 |  | 1,583 |  |
Changes in scope of consolidation |  | (26) | 93 |  | 15 |  |
Acquisitions and other increases |  | 292 | 963 |  | 340 |  |
Disposals and other decreases |  | (232) | (91) |  | (121) |  |
Currency translation differences |  | 101 | 76 |  | (85) |  |
Transfers |  | (8) | (7) |  | (21) |  |
Right-of-use assets at end of period |  | 2,872 | 2,745 |  | 1,711 |  |
Right-of-use assets |  | 2,872 | 2,745 |  | 1,711 |  | 1,583
Accumulated depreciation & impairment |  |  |  |  |  |  |
Disclosure of detailed information about property, plant and equipment [line items] |  |  |  |  |  |  |
Right-of-use assets at beginning of period |  | (797) | (513) |  | (283) |  |
Changes in scope of consolidation |  | 14 |  |  |  |  |
Disposals and other decreases |  | 82 | 40 |  | 44 |  |
Currency translation differences |  | (17) | (15) |  | 22 |  |
Transfers |  | 2 | 6 |  | 3 |  |
Depreciation and impairment charged in the period |  | (341) | (315) |  | (299) |  |
Right-of-use assets at end of period |  | (1,057) | (797) |  | (513) |  |
Right-of-use assets |  | € (1,057) | € (797) |  | € (513) |  | € (283)
[1] | Includes the impacts of the IFRIC final agenda decisions of March 2021 on the costs of configuring or customising application software used in a Software as a Service (SaaS) arrangement and of April 2021 on the attribution of benefits to periods of service, as described in Note A.2.1. to the consolidated financial statements for the year ended December 31, 2021.

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- Definition The amount of depreciation of right-of-use assets. [Refer: Depreciation and amortisation expense; Right-of-use assets] + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IFRS -Number 16 -IssueDate 2021-01-01 -Paragraph 53 -Subparagraph a -URI http://eifrs.ifrs.org/eifrs/xifrs-link?type=IFRS&num=16&code=ifrs-tx-2021-en-r&anchor=para_53_a&doctype=Standard -URIDate 2021-03-24 + Details
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- Definition The amount of liabilities related to the entity's leases. Lease is a contract, or part of a contract, that conveys the right to use an underlying asset for a period of time in exchange for consideration. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IFRS -Number 16 -IssueDate 2021-01-01 -Paragraph 47 -Subparagraph b -URI http://eifrs.ifrs.org/eifrs/xifrs-link?type=IFRS&num=16&code=ifrs-tx-2021-en-r&anchor=para_47_b&doctype=Standard -URIDate 2021-03-24 + Details
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- Definition The amount of assets that represent a lessee's right to use an underlying asset for the lease term. Underlying asset is an asset that is the subject of a lease, for which the right to use that asset has been provided by a lessor to a lessee. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Name IFRS -Number 16 -IssueDate 2021-01-01 -Paragraph 53 -Subparagraph j -URI http://eifrs.ifrs.org/eifrs/xifrs-link?type=IFRS&num=16&code=ifrs-tx-2021-en-r&anchor=para_53_j&doctype=Standard -URIDate 2021-03-24 + Details
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- Definition Acquisition Through Business Combinations, Property, Plant and Equipment, Right Of Use Assets + References No definition available. + Details
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- Definition Additions Other Than Through Business Combinations, Property, Plant and Equipment, Right Of Use Assets + References No definition available. + Details
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- Definition Disposals And Retirements, Property, Plant And Equipment, Right Of Use Assets + References No definition available. + Details
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- Definition Increase (Decrease) Through Net Exchange Differences, Property, Plant and Equipment, Right Of Use Assets + References No definition available. + Details
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- Definition Increase (Decrease) Through Transfers, Property, Plant and Equipment, Right Of Use Assets + References No definition available. + Details
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- Definition Number Of Lease Agreements Signed + References No definition available. + Details
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