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Off balance sheet commitments - Additional Information (Details)
€ in Millions, $ in Millions
3 Months Ended 9 Months Ended 12 Months Ended
Oct. 04, 2023
EUR (€)
Oct. 04, 2023
USD ($)
Oct. 03, 2023
USD ($)
Jun. 19, 2023
USD ($)
Mar. 15, 2022
EUR (€)
Feb. 27, 2017
EUR (€)
Mar. 31, 2022
Dec. 31, 2022
EUR (€)
Dec. 31, 2023
EUR (€)
Dec. 31, 2022
EUR (€)
Oct. 04, 2023
USD ($)
Apr. 27, 2023
EUR (€)
Dec. 31, 2022
USD ($)
Nov. 08, 2022
target
Aug. 17, 2022
target
Mar. 29, 2022
target
Jan. 07, 2022
molecule
Dec. 31, 2021
EUR (€)
Apr. 08, 2021
USD ($)
Feb. 28, 2014
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to research and development relating to projects in research phase               € 18,000 € 16,800 € 18,000                    
Commitments related to research and development payments contingent upon attainment of sales targets               18,500 17,900 18,500                    
Commitments related to collaboration, discovery, development and commercialization agreements               8,800 10,000 8,800                    
Commitments related to attainment of regulatory and sales milestones for commercialized products               7,600 8,500 7,600                    
Cumulative development costs incurred                 8,600                      
Total credit facilities               € 8,000 € 8,000 € 8,000               € 8,000    
Commitments received in respect of disposals proceeds receivable and contingent consideration on divestments | $                         $ 300              
World Health Organization                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Percentage of pandemic vaccines agreed to transfer                                       7.50%
Percentage of pandemic vaccines agreed to reserve                                       7.50%
Joint ventures                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Percentage of future development expense funded by other party           5000.00%                            
Scribe Therapeutics                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Upfront payment | $       $ 40                                
Scribe Therapeutics | Maximum                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to milestone payments for projects under collaboration agreements | $       $ 1,200                                
Janssen Pharmaceuticals, Inc                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Upfront payment | $     $ 175                                  
Teva Pharmaceuticals                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Upfront payment € 469 $ 500                                    
Teva Pharmaceuticals | Maximum                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to milestone payments for projects under collaboration agreements € 940                   $ 1,000                  
Provention Bio, Inc | Maximum                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to milestone payments for projects under collaboration agreements                       € 946                
Exscientia | Maximum                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Number of novel small molecule candidates developed | molecule                                 15      
IGM Biosciences, Inc | Maximum                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Number of oncology targets under collaboration agreement | target                               3        
Number of immunology or inflammation targets under collaboration agreement | target                               3        
Atomwise | Maximum                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Number of drug targets under collaboration agreement | target                             5          
Insilico Medicine | Maximum                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Number of therapeutic targets under collaboration agreement | target                           6            
Lonza | Joint ventures                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Investments in joint ventures           € 300                            
Percentage of future development expense funded by company           50.00%                            
Amounts payable partners in collaboration agreements           € 600                            
Antibodies Collaboration agreement | Blackstone Life Sciences                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to maximum payments for projects under collaboration agreement         € 300                              
Antibodies Collaboration agreement | Regeneron Pharmaceuticals, INC                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Maximum additional profit-share, in percentage of Regeneron's quarterly profit (in percent)             10.00% 20.00%                        
Percentage of cumulative development costs reimbursed                 50.00% 50.00%                    
Commitments received for development costs               € 2,700 € 2,100 € 2,700                    
Ablynx NV                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to collaboration, discovery, development and commercialization agreements               1,000 900 1,000                    
Kymab                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to collaboration, discovery, development and commercialization agreements               € 200 200 € 200                    
Commitments related to milestone payments for projects under collaboration agreements | $                                     $ 350  
Provention Bio                                        
Provisions And Other Current And Non-Current Liabilities [Line Items]                                        
Commitments related to collaboration, discovery, development and commercialization agreements                 € 300