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Principal alliances - Immuno-Oncology Agreement with Regeneron Pharmaceuticals, Inc. (Details)
€ in Millions, $ in Millions
1 Months Ended 12 Months Ended
Sep. 30, 2021
USD ($)
Jul. 01, 2015
agreement
Nov. 30, 2022
EUR (€)
Nov. 30, 2022
USD ($)
Jul. 31, 2022
EUR (€)
Jul. 31, 2022
USD ($)
Dec. 31, 2023
EUR (€)
Dec. 31, 2022
EUR (€)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
EUR (€)
Dec. 31, 2015
USD ($)
Disclosure of Principal Alliances [Line Items]                      
Other operating income/(expenses), net related to Regeneron | €             € (2,979) € (1,231)   € (1,373)  
Assets held for sale or exchange | €             15 85   € 89  
Regeneron Pharmaceuticals, INC                      
Disclosure of Principal Alliances [Line Items]                      
Assets held for sale or exchange | €               226      
Regeneron Pharmaceuticals, INC | Immuno-oncology collaboration agreement                      
Disclosure of Principal Alliances [Line Items]                      
Number of agreements signed | agreement   2                  
Maximum additional profit-share, in percentage of Regeneron's quarterly profit (in percent)                     10.00%
Percentage of cumulative development costs reimbursed                     50.00%
Upfront payments for projects under collaboration agreements | $                 $ 900    
Regular milestone payments for projects under collaboration agreements     € 96 $ 100         $ 100    
Regeneron Pharmaceuticals, INC | Immuno-oncology collaboration agreement | Major Collaboration Agreement                      
Disclosure of Principal Alliances [Line Items]                      
Upfront payments for projects under collaboration agreements         € 856 $ 900          
Royalty income percentage (percentage)         11.00% 11.00%          
Other operating income/(expenses), net related to Regeneron | €             116 111      
Proceeds from collaboration agreements | €             € 196 € 952      
Regeneron Pharmaceuticals, INC | Immuno-oncology collaboration agreement | Development of cemiplimab (REGN2810)                      
Disclosure of Principal Alliances [Line Items]                      
Prior development budget in total | $                     $ 1,640
Contractual agreement for anti-programmed cell death protein                     5000.00%
Maximum additional funding for PD1 - part of each company | $ $ 1,840                   $ 820
PD1 sales milestone payment from Sanofi | $                     375
Minimum sales of PD1 in 12-month period to be achieved for milestone payment | $                     $ 2,000