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Acquisitions, Divestitures, Research Collaborations and License Agreements - Narrative (Details) - USD ($)
$ in Millions
1 Months Ended
Mar. 31, 2017
Jan. 31, 2016
Dec. 31, 2016
Mar. 31, 2016
Dec. 31, 2015
Acquisitions Divestitures Research Collaborations And License Agreements Transactions [Line Items]          
Goodwill $ 18,358   $ 18,162    
Contingent consideration $ 925   $ 891 $ 652 $ 590
Vallee SA          
Acquisitions Divestitures Research Collaborations And License Agreements Transactions [Line Items]          
Percentage of business acquired (as percent) 93.50%        
Cash paid for acquisition of business $ 358        
Escrow deposit 176        
Intangible assets 297        
Deferred tax liabilities noncurrent 95        
Other net assets 1        
Noncontrolling interest 25        
Contingent liabilities 37        
Indemnification assets 37        
Goodwill $ 180        
Discount rate (as percent) 15.50%        
Acquired finite-lived intangible assets, weighted average useful life 15 years        
IOmet Pharma Ltd          
Acquisitions Divestitures Research Collaborations And License Agreements Transactions [Line Items]          
Cash paid for acquisition of business   $ 150      
Goodwill   $ 57      
Discount rate (as percent)   10.50%      
Amount of potential future additional payments for milestones, maximum   $ 250      
Contingent consideration   94      
In-process research and development (IPR&D)   155      
Deferred tax assets noncurrent   $ 32