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Segment Reporting - Sales of Company's Products (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2017
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Segment Reporting Information [Line Items]        
Sales $ 9,930 $ 9,844 $ 19,365 $ 19,156
Proceeds from sale of marketing rights     50 75
corticotropin marketing rights        
Segment Reporting Information [Line Items]        
Proceeds from sale of marketing rights       75
Operating Segments        
Segment Reporting Information [Line Items]        
Sales 9,815 9,680 19,033 18,689
Operating Segments | Total Pharmaceutical segment sales        
Segment Reporting Information [Line Items]        
Sales 8,759 8,700 16,944 16,804
Operating Segments | Total Pharmaceutical segment sales | Zetia        
Segment Reporting Information [Line Items]        
Sales 367 702 701 1,314
Operating Segments | Total Pharmaceutical segment sales | Vytorin        
Segment Reporting Information [Line Items]        
Sales 182 293 423 570
Operating Segments | Total Pharmaceutical segment sales | Atozet        
Segment Reporting Information [Line Items]        
Sales 63 33 112 56
Operating Segments | Total Pharmaceutical segment sales | Adempas        
Segment Reporting Information [Line Items]        
Sales 67 40 151 72
Operating Segments | Total Pharmaceutical segment sales | Januvia        
Segment Reporting Information [Line Items]        
Sales 948 1,064 1,787 1,970
Operating Segments | Total Pharmaceutical segment sales | Janumet        
Segment Reporting Information [Line Items]        
Sales 563 569 1,059 1,075
Operating Segments | Total Pharmaceutical segment sales | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 199 200 359 376
Operating Segments | Total Pharmaceutical segment sales | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 178 164 349 298
Operating Segments | Total Pharmaceutical segment sales | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 79 73 160 167
Operating Segments | Total Pharmaceutical segment sales | Zepatier        
Segment Reporting Information [Line Items]        
Sales 517 112 895 161
Operating Segments | Total Pharmaceutical segment sales | Isentress/Isentress HD        
Segment Reporting Information [Line Items]        
Sales 282 338 587 678
Operating Segments | Total Pharmaceutical segment sales | Bridion        
Segment Reporting Information [Line Items]        
Sales 163 113 310 204
Operating Segments | Total Pharmaceutical segment sales | Noxafil        
Segment Reporting Information [Line Items]        
Sales 155 143 296 288
Operating Segments | Total Pharmaceutical segment sales | Invanz        
Segment Reporting Information [Line Items]        
Sales 150 143 286 257
Operating Segments | Total Pharmaceutical segment sales | Cancidas        
Segment Reporting Information [Line Items]        
Sales 112 131 233 263
Operating Segments | Total Pharmaceutical segment sales | Cubicin        
Segment Reporting Information [Line Items]        
Sales 103 357 198 649
Operating Segments | Total Pharmaceutical segment sales | Primaxin        
Segment Reporting Information [Line Items]        
Sales 71 81 133 154
Operating Segments | Total Pharmaceutical segment sales | Remicade        
Segment Reporting Information [Line Items]        
Sales 208 339 437 688
Operating Segments | Total Pharmaceutical segment sales | Simponi        
Segment Reporting Information [Line Items]        
Sales 199 199 383 387
Operating Segments | Total Pharmaceutical segment sales | Keytruda        
Segment Reporting Information [Line Items]        
Sales 881 314 1,465 563
Operating Segments | Total Pharmaceutical segment sales | Emend        
Segment Reporting Information [Line Items]        
Sales 143 143 276 268
Operating Segments | Total Pharmaceutical segment sales | Temodar        
Segment Reporting Information [Line Items]        
Sales 65 73 130 139
Operating Segments | Total Pharmaceutical segment sales | Singulair        
Segment Reporting Information [Line Items]        
Sales 203 229 389 465
Operating Segments | Total Pharmaceutical segment sales | Nasonex        
Segment Reporting Information [Line Items]        
Sales 85 101 224 331
Operating Segments | Total Pharmaceutical segment sales | Dulera        
Segment Reporting Information [Line Items]        
Sales 69 121 151 234
Operating Segments | Total Pharmaceutical segment sales | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 119 132 231 258
Operating Segments | Total Pharmaceutical segment sales | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 89 117 192 228
Operating Segments | Total Pharmaceutical segment sales | Fosamax        
Segment Reporting Information [Line Items]        
Sales 66 73 127 148
Operating Segments | Total Pharmaceutical segment sales | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 469 393 1,001 770
Operating Segments | Total Pharmaceutical segment sales | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 399 383 754 739
Operating Segments | Total Pharmaceutical segment sales | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 123 130 347 318
Operating Segments | Total Pharmaceutical segment sales | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 166 120 329 228
Operating Segments | Total Pharmaceutical segment sales | Zostavax        
Segment Reporting Information [Line Items]        
Sales 160 149 313 274
Operating Segments | Total Pharmaceutical segment sales | Other Pharmaceutical        
Segment Reporting Information [Line Items]        
Sales 1,116 1,128 2,156 2,214
Operating Segments | Other segment sales        
Segment Reporting Information [Line Items]        
Sales 1,056 980 2,089 1,885
Other        
Segment Reporting Information [Line Items]        
Sales $ 115 $ 164 $ 332 $ 467