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Segment Reporting - Sales of Company's Products (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Jan. 31, 2016
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Segment Reporting Information [Line Items]          
Sales   $ 10,325 $ 10,536 $ 29,689 $ 29,692
Proceeds from sale of marketing rights       60 75
Corticotropin marketing rights          
Segment Reporting Information [Line Items]          
Proceeds from sale of marketing rights $ 75        
Operating Segments          
Segment Reporting Information [Line Items]          
Sales   10,256 10,420 29,289 29,109
Operating Segments | Total Pharmaceutical segment sales          
Segment Reporting Information [Line Items]          
Sales   9,156 9,443 26,101 26,247
Operating Segments | Total Pharmaceutical segment sales | Zetia          
Segment Reporting Information [Line Items]          
Sales   320 671 1,021 1,985
Operating Segments | Total Pharmaceutical segment sales | Vytorin          
Segment Reporting Information [Line Items]          
Sales   142 273 565 843
Operating Segments | Total Pharmaceutical segment sales | Atozet          
Segment Reporting Information [Line Items]          
Sales   59 39 171 96
Operating Segments | Total Pharmaceutical segment sales | Adempas          
Segment Reporting Information [Line Items]          
Sales   70 48 221 120
Operating Segments | Total Pharmaceutical segment sales | Januvia          
Segment Reporting Information [Line Items]          
Sales   1,012 1,006 2,799 2,976
Operating Segments | Total Pharmaceutical segment sales | Janumet          
Segment Reporting Information [Line Items]          
Sales   513 548 1,572 1,624
Operating Segments | Total Pharmaceutical segment sales | NuvaRing          
Segment Reporting Information [Line Items]          
Sales   214 195 573 571
Operating Segments | Total Pharmaceutical segment sales | Implanon/Nexplanon          
Segment Reporting Information [Line Items]          
Sales   155 148 503 446
Operating Segments | Total Pharmaceutical segment sales | Follistim AQ          
Segment Reporting Information [Line Items]          
Sales   72 101 232 268
Operating Segments | Total Pharmaceutical segment sales | Zepatier          
Segment Reporting Information [Line Items]          
Sales   468 164 1,363 326
Operating Segments | Total Pharmaceutical segment sales | Isentress/Isentress HD          
Segment Reporting Information [Line Items]          
Sales   310 372 896 1,050
Operating Segments | Total Pharmaceutical segment sales | Bridion          
Segment Reporting Information [Line Items]          
Sales   185 139 495 343
Operating Segments | Total Pharmaceutical segment sales | Noxafil          
Segment Reporting Information [Line Items]          
Sales   162 147 458 434
Operating Segments | Total Pharmaceutical segment sales | Invanz          
Segment Reporting Information [Line Items]          
Sales   159 152 445 409
Operating Segments | Total Pharmaceutical segment sales | Cancidas          
Segment Reporting Information [Line Items]          
Sales   94 142 327 406
Operating Segments | Total Pharmaceutical segment sales | Cubicin          
Segment Reporting Information [Line Items]          
Sales   91 320 290 969
Operating Segments | Total Pharmaceutical segment sales | Primaxin          
Segment Reporting Information [Line Items]          
Sales   73 77 206 231
Operating Segments | Total Pharmaceutical segment sales | Remicade          
Segment Reporting Information [Line Items]          
Sales   214 311 651 999
Operating Segments | Total Pharmaceutical segment sales | Simponi          
Segment Reporting Information [Line Items]          
Sales   219 193 602 581
Operating Segments | Total Pharmaceutical segment sales | Keytruda          
Segment Reporting Information [Line Items]          
Sales   1,047 356 2,512 919
Operating Segments | Total Pharmaceutical segment sales | Emend          
Segment Reporting Information [Line Items]          
Sales   137 137 413 405
Operating Segments | Total Pharmaceutical segment sales | Temodar          
Segment Reporting Information [Line Items]          
Sales   68 78 198 216
Operating Segments | Total Pharmaceutical segment sales | Singulair          
Segment Reporting Information [Line Items]          
Sales   161 239 550 705
Operating Segments | Total Pharmaceutical segment sales | Nasonex          
Segment Reporting Information [Line Items]          
Sales   42 94 266 425
Operating Segments | Total Pharmaceutical segment sales | Dulera          
Segment Reporting Information [Line Items]          
Sales   59 97 210 331
Operating Segments | Total Pharmaceutical segment sales | Cozaar/Hyzaar          
Segment Reporting Information [Line Items]          
Sales   128 131 360 389
Operating Segments | Total Pharmaceutical segment sales | Arcoxia          
Segment Reporting Information [Line Items]          
Sales   80 114 272 342
Operating Segments | Total Pharmaceutical segment sales | Fosamax          
Segment Reporting Information [Line Items]          
Sales   53 68 180 217
Operating Segments | Total Pharmaceutical segment sales | Gardasil/Gardasil 9          
Segment Reporting Information [Line Items]          
Sales   675 860 1,675 1,631
Operating Segments | Total Pharmaceutical segment sales | ProQuad/M-M-R II/Varivax          
Segment Reporting Information [Line Items]          
Sales   519 496 1,273 1,236
Operating Segments | Total Pharmaceutical segment sales | Pneumovax 23          
Segment Reporting Information [Line Items]          
Sales   229 175 558 403
Operating Segments | Total Pharmaceutical segment sales | Zostavax          
Segment Reporting Information [Line Items]          
Sales   234 190 547 464
Operating Segments | Total Pharmaceutical segment sales | RotaTeq          
Segment Reporting Information [Line Items]          
Sales   179 171 525 489
Operating Segments | Total Pharmaceutical segment sales | Other Pharmaceutical          
Segment Reporting Information [Line Items]          
Sales   1,013 1,191 3,172 3,398
Operating Segments | Other segment sales          
Segment Reporting Information [Line Items]          
Sales   1,100 977 3,188 2,862
Other          
Segment Reporting Information [Line Items]          
Sales   $ 69 $ 116 $ 400 $ 583