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Segment Reporting - Reconciliation of Segment Profits to Income Before Taxes (Details) - USD ($) $ in Millions | 1 Months Ended | 12 Months Ended
--- | --- | ---
Feb. 28, 2017 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Segment Reporting Information [Line Items] |  |  |  |
Interest income |  | $ 385 | $ 328 | $ 289
Interest expense |  | (754) | (693) | (672)
Equity income from affiliates |  | 42 | 86 | 205
Depreciation and amortization |  | (4,637) | (5,441) | (6,375)
Research and development |  | (10,208) | (10,124) | (6,704)
Restructuring costs |  | (776) | (651) | (619)
Loss on extinguishment of debt |  | (191) |  |
Charge related to the settlement of worldwide Keytruda patent litigation | $ (80) | 0 | (625) | 0
Foreign currency devaluation related to Venezuela |  | 0 | 0 | (876)
Net charge related to the settlement of Vioxx shareholder class action litigation |  | 0 | 0 | 680
Income Before Taxes |  | 6,521 | 4,659 | 5,401
Total segment profits |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Equity income from affiliates |  | (7) | 105 | 70
Depreciation and amortization |  | (212) | (183) | (100)
Income Before Taxes |  | 24,420 | 23,687 | 23,231
Total segment profits | Pharmaceutical segment |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Equity income from affiliates |  | (7) | 105 | 70
Depreciation and amortization |  | (125) | (160) | (82)
Income Before Taxes |  | 22,586 | 22,180 | 21,658
Total segment profits | Other segments |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Equity income from affiliates |  | 0 | 0 | 0
Depreciation and amortization |  | (87) | (23) | (18)
Income Before Taxes |  | 1,834 | 1,507 | 1,573
Other profits |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Income Before Taxes |  | 26 | 481 | 810
Unallocated |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Interest income |  | 385 | 328 | 289
Interest expense |  | (754) | (693) | (672)
Equity income from affiliates |  | 49 | (19) | 135
Depreciation and amortization |  | (1,378) | (1,585) | (1,573)
Research and development |  | (9,355) | (9,084) | (5,871)
Amortization of purchase accounting adjustments |  | (3,056) | (3,692) | (4,816)
Restructuring costs |  | (776) | (651) | (619)
Loss on extinguishment of debt |  | (191) | 0 | 0
Gain on sale of certain migraine clinical development programs |  | 0 | 100 | 250
Charge related to the settlement of worldwide Keytruda patent litigation |  | 0 | (625) | 0
Gain on divestiture of certain ophthalmic products |  | 0 | 0 | 147
Foreign currency devaluation related to Venezuela |  | 0 | 0 | (876)
Net charge related to the settlement of Vioxx shareholder class action litigation |  | 0 | 0 | (680)
Other unallocated, net |  | $ (2,849) | $ (3,588) | $ (4,354)

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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 985 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756 + Details
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