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Collaborative Arrangements - Narrative (Details) - USD ($) $ in Millions | 1 Months Ended | 12 Months Ended
--- | --- | ---
Jan. 31, 2018 | Dec. 31, 2017 | Jul. 31, 2017 | Dec. 31, 2019 | Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Research and development |  |  |  |  |  | $ 10,208 | $ 10,124 | $ 6,704
Sales |  |  |  |  |  | 40,122 | 39,807 | 39,498
Accrued and other current liabilities |  | $ 10,427 |  |  |  | 10,427 | 10,274 |
Other Noncurrent Liabilities |  | 11,117 |  |  |  | 11,117 | 8,514 |
Amortization expense for intangible assets |  |  |  |  |  | 3,200 | 3,800 | $ 4,800
AstraZeneca |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Upfront and milestone payments |  |  | $ 1,600 |  |  |  |  |
Payments to Acquire Intangible Assets |  | 250 | 750 |  |  |  |  |
Research and development |  |  |  |  |  | 2,350 |  |
Contingent Payments Collaborative Arrangement |  |  | 6,150 |  |  |  |  |
Total Consideration Collaborative Arrangement |  |  | 8,500 |  |  |  |  |
AstraZeneca | Future Regulatory Milestones [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent Payments Collaborative Arrangement |  |  | 2,050 |  |  |  |  |
AstraZeneca | Future Sales-Based Milestones [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent Payments Collaborative Arrangement |  |  | $ 4,100 |  |  | 4,000 |  |
AstraZeneca | Forecast |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Payments to Acquire Intangible Assets |  |  |  | $ 100 | $ 400 |  |  |
AstraZeneca | Lynparza |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Accrued and other current liabilities |  | $ 100 |  |  |  | 100 |  |
Amortization expense for intangible assets |  |  |  |  |  | $ 4 |  |
Finite-Lived Intangible Assets, Remaining Amortization Period |  |  |  |  |  | 11 years |  |
AstraZeneca | Lynparza | Forecast |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent Payments Collaborative Arrangement |  |  |  |  | 100 |  |  |
Sales |  |  |  |  | $ 250 |  |  |
AstraZeneca | Subsequent Event |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent Payments Collaborative Arrangement | $ 70 |  |  |  |  |  |  |
Bayer AG | Future Sales-Based Milestones [Member] |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent Payments Collaborative Arrangement |  |  |  |  |  | $ 775 |  |
Bayer AG | Adempas |  |  |  |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent Payments Collaborative Arrangement |  |  |  |  |  |  | 350 |
Sales |  |  |  |  |  | $ 500 | 500 |
Other Noncurrent Liabilities |  |  |  |  |  |  | 350 |
Amortization expense for intangible assets |  |  |  |  |  |  | $ 50 |

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- Definition The aggregate costs incurred (1) in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or (2) to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, including the costs of developing computer software up to the point in time of achieving technological feasibility, and costs allocated in accounting for a business combination to in-process projects deemed to have no alternative future use. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 730 -SubTopic 10 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6420194&loc=d3e21568-108373 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 985 -SubTopic 20 -Section 50 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6501960&loc=d3e128462-111756 + Details
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