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Acquisitions, Divestitures, Research Collaborations and License Agreements - Divestitures Narrative (Detail) - USD ($) | 1 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Apr. 30, 2016 | Aug. 31, 2015 | Feb. 28, 2015 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015 | Jul. 31, 2015
Acquisitions Divestitures Research Collaborations and License Agreements Transactions [Line Items] |  |  |  |  |  |  |
Agreement term |  |  | 2 years |  |  |  |
Proceeds from sale of intangible assets |  |  |  | $ 85,000,000 | $ 170,000,000 |  |
ophthalmic products |  |  |  |  |  |  |
Acquisitions Divestitures Research Collaborations and License Agreements Transactions [Line Items] |  |  |  |  |  |  |
Proceeds from divestiture of business |  |  |  |  |  | $ 170,000,000 |
Gain on disposition of business |  |  |  |  |  | 147,000,000 |
CGRP receptor antagonists |  |  |  |  |  |  |
Acquisitions Divestitures Research Collaborations and License Agreements Transactions [Line Items] |  |  |  |  |  |  |
Total Consideration Received For Sale Of Asset |  |  |  |  |  |  | $ 250,000,000
Proceeds from collaborators | $ 125,000,000 | $ 125,000,000 |  |  |  |  |
Gain (loss) on sale of clinical development programs |  |  |  |  | $ 100,000,000 | $ 250,000,000 |

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- Definition Amount of gain (loss) on sale or disposal of intangible assets. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 225 -SubTopic 10 -Section S99 -Paragraph 2 -Subparagraph (SX 210.5-03.7,9) -URI http://asc.fasb.org/extlink&oid=63488584&loc=d3e20235-122688 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -URI http://asc.fasb.org/extlink&oid=98514028&loc=d3e3602-108585 + Details
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