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Segment Reporting - Sales of Company's Products (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Segment Reporting Information [Line Items]      
Sales $ 40,122 $ 39,807 $ 39,498
Proceeds from sale of intangible assets 85 170  
Operating Segments      
Segment Reporting Information [Line Items]      
Sales 39,662 39,013 38,449
Operating Segments | Pharmaceutical segment      
Segment Reporting Information [Line Items]      
Sales 35,390 35,151 34,782
Operating Segments | Pharmaceutical segment | Zetia      
Segment Reporting Information [Line Items]      
Sales 1,344 2,560 2,526
Operating Segments | Pharmaceutical segment | Vytorin      
Segment Reporting Information [Line Items]      
Sales 751 1,141 1,251
Operating Segments | Pharmaceutical segment | Atozet      
Segment Reporting Information [Line Items]      
Sales 225 146 36
Operating Segments | Pharmaceutical segment | Adempas      
Segment Reporting Information [Line Items]      
Sales 300 169 30
Operating Segments | Pharmaceutical segment | Januvia      
Segment Reporting Information [Line Items]      
Sales 3,737 3,908 3,863
Operating Segments | Pharmaceutical segment | Janumet      
Segment Reporting Information [Line Items]      
Sales 2,158 2,201 2,151
Operating Segments | Pharmaceutical segment | NuvaRing      
Segment Reporting Information [Line Items]      
Sales 761 777 732
Operating Segments | Pharmaceutical segment | Implanon/Nexplanon      
Segment Reporting Information [Line Items]      
Sales 686 606 588
Operating Segments | Pharmaceutical segment | Follistim AQ      
Segment Reporting Information [Line Items]      
Sales 298 355 383
Operating Segments | Pharmaceutical segment | Zepatier      
Segment Reporting Information [Line Items]      
Sales 1,660 555 0
Operating Segments | Pharmaceutical segment | Isentress/Isentress HD      
Segment Reporting Information [Line Items]      
Sales 1,204 1,387 1,511
Operating Segments | Pharmaceutical segment | Bridion      
Segment Reporting Information [Line Items]      
Sales 704 482 353
Operating Segments | Pharmaceutical segment | Noxafil      
Segment Reporting Information [Line Items]      
Sales 636 595 487
Operating Segments | Pharmaceutical segment | Invanz      
Segment Reporting Information [Line Items]      
Sales 602 561 569
Operating Segments | Pharmaceutical segment | Cancidas      
Segment Reporting Information [Line Items]      
Sales 422 558 573
Operating Segments | Pharmaceutical segment | Cubicin      
Segment Reporting Information [Line Items]      
Sales 382 1,087 1,127
Operating Segments | Pharmaceutical segment | Primaxin      
Segment Reporting Information [Line Items]      
Sales 280 297 313
Operating Segments | Pharmaceutical segment | Remicade      
Segment Reporting Information [Line Items]      
Sales 837 1,268 1,794
Operating Segments | Pharmaceutical segment | Simponi      
Segment Reporting Information [Line Items]      
Sales 819 766 690
Operating Segments | Pharmaceutical segment | Keytruda      
Segment Reporting Information [Line Items]      
Sales 3,809 1,402 566
Operating Segments | Pharmaceutical segment | Emend      
Segment Reporting Information [Line Items]      
Sales 556 549 535
Operating Segments | Pharmaceutical segment | Temodar      
Segment Reporting Information [Line Items]      
Sales 271 283 312
Operating Segments | Pharmaceutical segment | Singulair      
Segment Reporting Information [Line Items]      
Sales 732 915 931
Operating Segments | Pharmaceutical segment | Nasonex      
Segment Reporting Information [Line Items]      
Sales 387 537 858
Operating Segments | Pharmaceutical segment | Dulera      
Segment Reporting Information [Line Items]      
Sales 287 436 536
Operating Segments | Pharmaceutical segment | Cozaar/Hyzaar      
Segment Reporting Information [Line Items]      
Sales 484 511 667
Operating Segments | Pharmaceutical segment | Arcoxia      
Segment Reporting Information [Line Items]      
Sales 363 450 471
Operating Segments | Pharmaceutical segment | Fosamax      
Segment Reporting Information [Line Items]      
Sales 241 284 359
Operating Segments | Pharmaceutical segment | Gardasil/Gardasil 9      
Segment Reporting Information [Line Items]      
Sales 2,308 2,173 1,908
Operating Segments | Pharmaceutical segment | ProQuad/M-M-R II/Varivax      
Segment Reporting Information [Line Items]      
Sales 1,676 1,640 1,505
Operating Segments | Pharmaceutical segment | Pneumovax 23      
Segment Reporting Information [Line Items]      
Sales 821 641 542
Operating Segments | Pharmaceutical segment | RotaTeq      
Segment Reporting Information [Line Items]      
Sales 686 652 610
Operating Segments | Pharmaceutical segment | Zostavax      
Segment Reporting Information [Line Items]      
Sales 668 685 749
Operating Segments | Pharmaceutical segment | Other pharmaceutical      
Segment Reporting Information [Line Items]      
Sales 4,295 4,574 5,256
Operating Segments | Other segments      
Segment Reporting Information [Line Items]      
Sales 4,272 3,862 3,667
Other      
Segment Reporting Information [Line Items]      
Sales 460 794 1,049
United States      
Segment Reporting Information [Line Items]      
Sales 17,424 18,478 17,519
United States | Operating Segments      
Segment Reporting Information [Line Items]      
Sales 17,340 18,447 17,451
United States | Operating Segments | Pharmaceutical segment      
Segment Reporting Information [Line Items]      
Sales 15,854 17,073 16,238
United States | Operating Segments | Pharmaceutical segment | Zetia      
Segment Reporting Information [Line Items]      
Sales 352 1,588 1,612
United States | Operating Segments | Pharmaceutical segment | Vytorin      
Segment Reporting Information [Line Items]      
Sales 124 473 479
United States | Operating Segments | Pharmaceutical segment | Atozet      
Segment Reporting Information [Line Items]      
Sales 0 1 2
United States | Operating Segments | Pharmaceutical segment | Adempas      
Segment Reporting Information [Line Items]      
Sales 0 0 0
United States | Operating Segments | Pharmaceutical segment | Januvia      
Segment Reporting Information [Line Items]      
Sales 2,153 2,286 2,263
United States | Operating Segments | Pharmaceutical segment | Janumet      
Segment Reporting Information [Line Items]      
Sales 863 984 976
United States | Operating Segments | Pharmaceutical segment | NuvaRing      
Segment Reporting Information [Line Items]      
Sales 564 576 515
United States | Operating Segments | Pharmaceutical segment | Implanon/Nexplanon      
Segment Reporting Information [Line Items]      
Sales 496 420 367
United States | Operating Segments | Pharmaceutical segment | Follistim AQ      
Segment Reporting Information [Line Items]      
Sales 123 157 160
United States | Operating Segments | Pharmaceutical segment | Zepatier      
Segment Reporting Information [Line Items]      
Sales 771 488 0
United States | Operating Segments | Pharmaceutical segment | Isentress/Isentress HD      
Segment Reporting Information [Line Items]      
Sales 565 721 797
United States | Operating Segments | Pharmaceutical segment | Bridion      
Segment Reporting Information [Line Items]      
Sales 239 77 0
United States | Operating Segments | Pharmaceutical segment | Noxafil      
Segment Reporting Information [Line Items]      
Sales 309 284 212
United States | Operating Segments | Pharmaceutical segment | Invanz      
Segment Reporting Information [Line Items]      
Sales 361 329 322
United States | Operating Segments | Pharmaceutical segment | Cancidas      
Segment Reporting Information [Line Items]      
Sales 20 25 24
United States | Operating Segments | Pharmaceutical segment | Cubicin      
Segment Reporting Information [Line Items]      
Sales 189 906 1,030
United States | Operating Segments | Pharmaceutical segment | Primaxin      
Segment Reporting Information [Line Items]      
Sales 10 4 8
United States | Operating Segments | Pharmaceutical segment | Remicade      
Segment Reporting Information [Line Items]      
Sales 0 0 0
United States | Operating Segments | Pharmaceutical segment | Simponi      
Segment Reporting Information [Line Items]      
Sales 0 0 0
United States | Operating Segments | Pharmaceutical segment | Keytruda      
Segment Reporting Information [Line Items]      
Sales 2,309 792 393
United States | Operating Segments | Pharmaceutical segment | Emend      
Segment Reporting Information [Line Items]      
Sales 342 356 326
United States | Operating Segments | Pharmaceutical segment | Temodar      
Segment Reporting Information [Line Items]      
Sales 16 15 7
United States | Operating Segments | Pharmaceutical segment | Singulair      
Segment Reporting Information [Line Items]      
Sales 40 40 39
United States | Operating Segments | Pharmaceutical segment | Nasonex      
Segment Reporting Information [Line Items]      
Sales 54 184 449
United States | Operating Segments | Pharmaceutical segment | Dulera      
Segment Reporting Information [Line Items]      
Sales 261 412 515
United States | Operating Segments | Pharmaceutical segment | Cozaar/Hyzaar      
Segment Reporting Information [Line Items]      
Sales 18 16 30
United States | Operating Segments | Pharmaceutical segment | Arcoxia      
Segment Reporting Information [Line Items]      
Sales 0 0 0
United States | Operating Segments | Pharmaceutical segment | Fosamax      
Segment Reporting Information [Line Items]      
Sales 6 5 12
United States | Operating Segments | Pharmaceutical segment | Gardasil/Gardasil 9      
Segment Reporting Information [Line Items]      
Sales 1,565 1,780 1,520
United States | Operating Segments | Pharmaceutical segment | ProQuad/M-M-R II/Varivax      
Segment Reporting Information [Line Items]      
Sales 1,374 1,362 1,290
United States | Operating Segments | Pharmaceutical segment | Pneumovax 23      
Segment Reporting Information [Line Items]      
Sales 581 447 378
United States | Operating Segments | Pharmaceutical segment | RotaTeq      
Segment Reporting Information [Line Items]      
Sales 481 482 447
United States | Operating Segments | Pharmaceutical segment | Zostavax      
Segment Reporting Information [Line Items]      
Sales 422 518 592
United States | Operating Segments | Pharmaceutical segment | Other pharmaceutical      
Segment Reporting Information [Line Items]      
Sales 1,246 1,345 1,473
United States | Operating Segments | Other segments      
Segment Reporting Information [Line Items]      
Sales 1,486 1,374 1,213
United States | Other      
Segment Reporting Information [Line Items]      
Sales 84 31 68
Int’l      
Segment Reporting Information [Line Items]      
Sales 22,698 21,329 21,979
Int’l | Operating Segments      
Segment Reporting Information [Line Items]      
Sales 22,321 20,566 20,998
Int’l | Operating Segments | Pharmaceutical segment      
Segment Reporting Information [Line Items]      
Sales 19,536 18,077 18,544
Int’l | Operating Segments | Pharmaceutical segment | Zetia      
Segment Reporting Information [Line Items]      
Sales 992 972 914
Int’l | Operating Segments | Pharmaceutical segment | Vytorin      
Segment Reporting Information [Line Items]      
Sales 627 668 771
Int’l | Operating Segments | Pharmaceutical segment | Atozet      
Segment Reporting Information [Line Items]      
Sales 225 146 34
Int’l | Operating Segments | Pharmaceutical segment | Adempas      
Segment Reporting Information [Line Items]      
Sales 300 169 30
Int’l | Operating Segments | Pharmaceutical segment | Januvia      
Segment Reporting Information [Line Items]      
Sales 1,584 1,622 1,601
Int’l | Operating Segments | Pharmaceutical segment | Janumet      
Segment Reporting Information [Line Items]      
Sales 1,296 1,217 1,175
Int’l | Operating Segments | Pharmaceutical segment | NuvaRing      
Segment Reporting Information [Line Items]      
Sales 197 202 216
Int’l | Operating Segments | Pharmaceutical segment | Implanon/Nexplanon      
Segment Reporting Information [Line Items]      
Sales 191 186 221
Int’l | Operating Segments | Pharmaceutical segment | Follistim AQ      
Segment Reporting Information [Line Items]      
Sales 174 197 223
Int’l | Operating Segments | Pharmaceutical segment | Zepatier      
Segment Reporting Information [Line Items]      
Sales 888 67 0
Int’l | Operating Segments | Pharmaceutical segment | Isentress/Isentress HD      
Segment Reporting Information [Line Items]      
Sales 639 666 714
Int’l | Operating Segments | Pharmaceutical segment | Bridion      
Segment Reporting Information [Line Items]      
Sales 465 405 353
Int’l | Operating Segments | Pharmaceutical segment | Noxafil      
Segment Reporting Information [Line Items]      
Sales 327 312 275
Int’l | Operating Segments | Pharmaceutical segment | Invanz      
Segment Reporting Information [Line Items]      
Sales 241 233 247
Int’l | Operating Segments | Pharmaceutical segment | Cancidas      
Segment Reporting Information [Line Items]      
Sales 402 533 548
Int’l | Operating Segments | Pharmaceutical segment | Cubicin      
Segment Reporting Information [Line Items]      
Sales 193 181 97
Int’l | Operating Segments | Pharmaceutical segment | Primaxin      
Segment Reporting Information [Line Items]      
Sales 270 293 305
Int’l | Operating Segments | Pharmaceutical segment | Remicade      
Segment Reporting Information [Line Items]      
Sales 837 1,268 1,794
Int’l | Operating Segments | Pharmaceutical segment | Simponi      
Segment Reporting Information [Line Items]      
Sales 819 766 690
Int’l | Operating Segments | Pharmaceutical segment | Keytruda      
Segment Reporting Information [Line Items]      
Sales 1,500 610 173
Int’l | Operating Segments | Pharmaceutical segment | Emend      
Segment Reporting Information [Line Items]      
Sales 213 193 209
Int’l | Operating Segments | Pharmaceutical segment | Temodar      
Segment Reporting Information [Line Items]      
Sales 256 268 306
Int’l | Operating Segments | Pharmaceutical segment | Singulair      
Segment Reporting Information [Line Items]      
Sales 692 874 892
Int’l | Operating Segments | Pharmaceutical segment | Nasonex      
Segment Reporting Information [Line Items]      
Sales 333 352 409
Int’l | Operating Segments | Pharmaceutical segment | Dulera      
Segment Reporting Information [Line Items]      
Sales 26 24 21
Int’l | Operating Segments | Pharmaceutical segment | Cozaar/Hyzaar      
Segment Reporting Information [Line Items]      
Sales 466 494 637
Int’l | Operating Segments | Pharmaceutical segment | Arcoxia      
Segment Reporting Information [Line Items]      
Sales 363 450 471
Int’l | Operating Segments | Pharmaceutical segment | Fosamax      
Segment Reporting Information [Line Items]      
Sales 235 279 347
Int’l | Operating Segments | Pharmaceutical segment | Gardasil/Gardasil 9      
Segment Reporting Information [Line Items]      
Sales 743 393 388
Int’l | Operating Segments | Pharmaceutical segment | ProQuad/M-M-R II/Varivax      
Segment Reporting Information [Line Items]      
Sales 303 279 214
Int’l | Operating Segments | Pharmaceutical segment | Pneumovax 23      
Segment Reporting Information [Line Items]      
Sales 240 193 164
Int’l | Operating Segments | Pharmaceutical segment | RotaTeq      
Segment Reporting Information [Line Items]      
Sales 204 169 163
Int’l | Operating Segments | Pharmaceutical segment | Zostavax      
Segment Reporting Information [Line Items]      
Sales 246 168 157
Int’l | Operating Segments | Pharmaceutical segment | Other pharmaceutical      
Segment Reporting Information [Line Items]      
Sales 3,049 3,228 3,785
Int’l | Operating Segments | Other segments      
Segment Reporting Information [Line Items]      
Sales 2,785 2,489 2,454
Int’l | Other      
Segment Reporting Information [Line Items]      
Sales $ 377 $ 763 $ 981