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Goodwill and Other Intangibles - Narrative (Details) - USD ($)
$ in Millions
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net $ 14,183 $ 17,305  
Other intangibles, net 50,131 50,084  
Accumulated Amortization 35,948 32,779  
Intangible asset impairment charge related to marketed product 58 347 $ 45
IPR&D reclassified to products and product rights upon receipt of marketing approval 14 8 280
IPR&D impairment charges 483 3,600 63
Amortization expense for intangible assets 3,200 3,800 4,800
Estimated Future Amortization Expense, 2018 2,800    
Estimated Future Amortization Expense, 2019 1,500    
Estimated Future Amortization Expense, 2020 1,200    
Estimated Future Amortization Expense, 2021 1,100    
Estimated Future Amortization Expense, 2022 1,100    
Zerbaxa      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 3,000    
Sivextro      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 879    
Zetia      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 756    
Implanon/Nexplanon      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 529    
Dificid      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 478    
Gardasil/Gardasil 9      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 468 468  
Vytorin      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 375    
Bridion      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 320    
Simponi      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 226    
Adempas      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 894    
Intron A      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net 13    
Intangible asset impairment charge related to marketed product 47    
Zontivity      
Intangible Assets Excluding Goodwill [Line Items]      
Intangible asset impairment charge related to marketed product   252  
Grastek/Ragwitek      
Intangible Assets Excluding Goodwill [Line Items]      
Intangible asset impairment charge related to marketed product   95  
uprifosbuvir      
Intangible Assets Excluding Goodwill [Line Items]      
Other intangibles, net   240  
IPR&D impairment charges 240 2,900  
verubecestat [Member]      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges $ 226    
monoclonal antibody (cCAM)      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges   180  
BET inhibitor (OncoEthix)      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges   143  
diabetes treatment      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges   72  
House Dust Mite      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges   112  
Next Generation Ring      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges   $ 79  
surotomycin      
Intangible Assets Excluding Goodwill [Line Items]      
IPR&D impairment charges     $ 50