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Segment Reporting (Tables) | 3 Months Ended
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Mar. 31, 2018
Segment Reporting [Abstract] |
Sales of Company's products | Sales of the Company’s products were as follows:
| Three Months Ended March 31,
| 2018 |  | 2017
($ in millions) | U.S. |  | Int’l |  | Total |  | U.S. |  | Int’l |  | Total
Pharmaceutical: |  |  |  |  |  |  |  |  |  |  |
Oncology |  |  |  |  |  |  |  |  |  |  |
Keytruda | $ | 838 |  |  | $ | 626 |  |  | $ | 1,464 |  |  | $ | 361 |  |  | $ | 223 |  |  | $ | 584 |
Emend | 79 |  |  | 46 |  |  | 125 |  |  | 86 |  |  | 47 |  |  | 133 |
Temodar | 1 |  |  | 56 |  |  | 57 |  |  | 1 |  |  | 65 |  |  | 66 |
Alliance revenue - Lynparza | 24 |  |  | 9 |  |  | 33 |  |  | — |  |  | — |  |  | — |
Vaccines |  |  |  |  |  |  |  |  |  |  |
Gardasil/Gardasil 9 | 380 |  |  | 280 |  |  | 660 |  |  | 398 |  |  | 134 |  |  | 532 |
ProQuad/M-M-R II/Varivax | 312 |  |  | 80 |  |  | 392 |  |  | 298 |  |  | 57 |  |  | 355 |
RotaTeq | 151 |  |  | 42 |  |  | 193 |  |  | 178 |  |  | 45 |  |  | 224 |
Pneumovax 23 | 112 |  |  | 66 |  |  | 179 |  |  | 114 |  |  | 49 |  |  | 163 |
Zostavax | 16 |  |  | 48 |  |  | 65 |  |  | 109 |  |  | 45 |  |  | 154 |
Hospital Acute Care |  |  |  |  |  |  |  |  |  |  |
Bridion | 80 |  |  | 124 |  |  | 204 |  |  | 45 |  |  | 102 |  |  | 148 |
Noxafil | 81 |  |  | 94 |  |  | 176 |  |  | 65 |  |  | 76 |  |  | 141 |
Invanz | 91 |  |  | 60 |  |  | 151 |  |  | 82 |  |  | 54 |  |  | 136 |
Cubicin | 47 |  |  | 51 |  |  | 98 |  |  | 54 |  |  | 41 |  |  | 96 |
Cancidas | 3 |  |  | 88 |  |  | 91 |  |  | 5 |  |  | 116 |  |  | 121 |
Primaxin | 5 |  |  | 67 |  |  | 72 |  |  | — |  |  | 62 |  |  | 62 |
Immunology |  |  |  |  |  |  |  |  |  |  |
Simponi | — |  |  | 231 |  |  | 231 |  |  | — |  |  | 184 |  |  | 184 |
Remicade | — |  |  | 167 |  |  | 167 |  |  | — |  |  | 229 |  |  | 229 |
Neuroscience |  |  |  |  |  |  |  |  |  |  |
Belsomra | 23 |  |  | 31 |  |  | 54 |  |  | 20 |  |  | 21 |  |  | 42 |
Virology |  |  |  |  |  |  |  |  |  |  |
Isentress/Isentress HD | 128 |  |  | 152 |  |  | 281 |  |  | 143 |  |  | 162 |  |  | 305 |
Zepatier | — |  |  | 131 |  |  | 131 |  |  | 200 |  |  | 178 |  |  | 378 |
Cardiovascular |  |  |  |  |  |  |  |  |  |  |
Zetia | 17 |  |  | 287 |  |  | 305 |  |  | 111 |  |  | 222 |  |  | 334 |
Vytorin | 8 |  |  | 158 |  |  | 167 |  |  | 90 |  |  | 151 |  |  | 241 |
Atozet | — |  |  | 73 |  |  | 73 |  |  | — |  |  | 49 |  |  | 49 |
Adempas | — |  |  | 68 |  |  | 68 |  |  | — |  |  | 84 |  |  | 84 |
Diabetes |  |  |  |  |  |  |  |  |  |  |
Januvia | 465 |  |  | 416 |  |  | 880 |  |  | 507 |  |  | 332 |  |  | 839 |
Janumet | 192 |  |  | 352 |  |  | 544 |  |  | 195 |  |  | 302 |  |  | 496 |
Women’s Health |  |  |  |  |  |  |  |  |  |  |
NuvaRing | 171 |  |  | 46 |  |  | 216 |  |  | 113 |  |  | 47 |  |  | 160 |
Implanon/Nexplanon | 128 |  |  | 46 |  |  | 174 |  |  | 132 |  |  | 39 |  |  | 170 |
Diversified Brands |  |  |  |  |  |  |  |  |  |  |
Singulair | 6 |  |  | 170 |  |  | 175 |  |  | 6 |  |  | 180 |  |  | 186 |
Nasonex | 1 |  |  | 121 |  |  | 122 |  |  | 18 |  |  | 121 |  |  | 139 |
Cozaar/Hyzaar | 7 |  |  | 113 |  |  | 120 |  |  | 3 |  |  | 109 |  |  | 112 |
Arcoxia | — |  |  | 83 |  |  | 83 |  |  | — |  |  | 103 |  |  | 103 |
Follistim AQ | 29 |  |  | 39 |  |  | 67 |  |  | 42 |  |  | 40 |  |  | 81 |
Dulera | 50 |  |  | 7 |  |  | 57 |  |  | 75 |  |  | 7 |  |  | 82 |
Fosamax | (2 | ) |  | 57 |  |  | 55 |  |  | 1 |  |  | 60 |  |  | 61 |
Other pharmaceutical (1) | 273 |  |  | 717 |  |  | 989 |  |  | 309 |  |  | 688 |  |  | 995 |
Total Pharmaceutical segment sales | 3,716 |  |  | 5,202 |  |  | 8,919 |  |  | 3,761 |  |  | 4,424 |  |  | 8,185 |
Animal Health: |  |  |  |  |  |  |  |  |  |  |
Livestock | 124 |  |  | 529 |  |  | 652 |  |  | 119 |  |  | 459 |  |  | 578 |
Companion Animals | 183 |  |  | 229 |  |  | 413 |  |  | 164 |  |  | 197 |  |  | 361 |
Total Animal Health segment sales | 307 |  |  | 758 |  |  | 1,065 |  |  | 283 |  |  | 656 |  |  | 939 |
Other segment sales (2) | 84 |  |  | — |  |  | 84 |  |  | 94 |  |  | — |  |  | 94 |
Total segment sales | 4,107 |  |  | 5,960 |  |  | 10,068 |  |  | 4,138 |  |  | 5,080 |  |  | 9,218 |
Other (3) | 26 |  |  | (56 | ) |  | (31 | ) |  | 57 |  |  | 159 |  |  | 216 |
| $ | 4,133 |  |  | $ | 5,904 |  |  | $ | 10,037 |  |  | $ | 4,195 |  |  | $ | 5,239 |  |  | $ | 9,434 |
(1) | Other pharmaceutical primarily reflects sales of other human health pharmaceutical products, including products within the franchises not listed separately.
(2) | Represents the non-reportable segments of Healthcare Services and Alliances.
(3) | Other is primarily comprised of miscellaneous corporate revenues, including revenue hedging activities, as well as third-party manufacturing sales. Other in the first quarter of 2018 and 2017 also includes $21 million and $50 million, respectively, related to the sale of the marketing rights to certain products.
Consolidated revenues by geographic area | Consolidated revenues by geographic area where derived are as follows:
| Three Months Ended March 31,
($ in millions) | 2018 |  | 2017
United States | $ | 4,133 |  |  | $ | 4,195 |
Europe, Middle East and Africa | 3,191 |  |  | 2,629 |
Asia Pacific | 1,238 |  |  | 1,001 |
Japan | 737 |  |  | 705 |
Latin America | 532 |  |  | 485 |
Other | 206 |  |  | 419 |
| $ | 10,037 |  |  | $ | 9,434 |
Reconciliation of segment profits to income before taxes | A reconciliation of segment profits to Income before taxes is as follows:
| Three Months Ended March 31,
($ in millions) | 2018 |  | 2017
Segment profits: |  |  |
Pharmaceutical segment | $ | 5,804 |  |  | $ | 5,160 |
Animal Health segment | 413 |  |  | 417 |
Other segments | 63 |  |  | 33 |
Total segment profits | 6,280 |  |  | 5,610 |
Other profits | (87 | ) |  | 142 |
Unallocated: |  |  |
Interest income | 85 |  |  | 97 |
Interest expense | (185 | ) |  | (182 | )
Equity income from affiliates | (50 | ) |  | (12 | )
Depreciation and amortization | (350 | ) |  | (370 | )
Research and development | (2,982 | ) |  | (1,632 | )
Amortization of purchase accounting adjustments | (733 | ) |  | (778 | )
Restructuring costs | (95 | ) |  | (151 | )
Other unallocated, net | (538 | ) |  | (721 | )
| $ | 1,345 |  |  | $ | 2,003 |

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