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Acquisitions, Research Collaborations and License Agreements - Acquisitions Narrative (Details)
$ / shares in Units, $ in Millions, $ in Millions
1 Months Ended 3 Months Ended
Feb. 28, 2018
AUD ($)
$ / shares
Feb. 28, 2018
USD ($)
Mar. 31, 2017
USD ($)
Dec. 31, 2017
USD ($)
Mar. 31, 2018
USD ($)
Acquisitions Divestitures Research Collaborations And License Agreements Transactions [Line Items]          
Business acquisition, price per share | $ / shares $ 1.75        
Future consideration to be transferred $ 502 $ 394      
Goodwill       $ 18,284 $ 18,304
Vallee SA          
Acquisitions Divestitures Research Collaborations And License Agreements Transactions [Line Items]          
Percentage of business acquired (as percent)     93.50% 4.50%  
Cash paid for acquisition of business     $ 358    
Escrow deposit     176    
Intangible assets     297    
Deferred tax liabilities noncurrent     102    
Other net assets     32    
Noncontrolling interest     25    
Contingent liabilities     37    
Indemnification assets     37    
Goodwill     $ 156    
Discount rate (as percent)     15.50%    
Acquired finite-lived intangible assets, weighted average useful life     15 years    
Payments to acquire additional interest in subsidiary       $ 18