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Segment Reporting - Reconciliation of Segment Profits to Income Before Taxes (Details) - USD ($) $ in Millions | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2018 | Jun. 30, 2017 | Jun. 30, 2018 | Jun. 30, 2017
Segment Reporting Information [Line Items] |  |  |  |
Profits | $ 2,086 | $ 2,439 | $ 3,432 | $ 4,442
Interest income | 81 | 96 | 165 | 194
Interest expense | (194) | (193) | (379) | (375)
Equity income from affiliates | 64 | 5 | 12 | (8)
Depreciation and amortization |  |  | (2,363) | (2,355)
Research and development | (2,274) | (1,782) | (5,470) | (3,612)
Restructuring costs | (228) | (166) | (323) | (317)
Total segment profits |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Profits | 6,302 | 6,096 | 12,582 | 11,707
Total segment profits | Pharmaceutical segment |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Profits | 5,826 | 5,590 | 11,630 | 10,751
Total segment profits | Animal Health segment |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Profits | 450 | 395 | 864 | 812
Total segment profits | Other segments |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Profits | 26 | 111 | 88 | 144
Other profits |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Profits | (2) | 43 | (89) | 186
Unallocated |  |  |  |
Segment Reporting Information [Line Items] |  |  |  |
Interest income | 81 | 96 | 165 | 194
Interest expense | (194) | (193) | (379) | (375)
Equity income from affiliates | 66 | 5 | 16 | (7)
Depreciation and amortization | (332) | (332) | (682) | (702)
Research and development | (2,041) | (1,560) | (5,023) | (3,191)
Amortization of purchase accounting adjustments | (732) | (779) | (1,464) | (1,557)
Restructuring costs | (228) | (166) | (323) | (317)
Other unallocated, net | $ (834) | $ (771) | $ (1,371) | $ (1,496)

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