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CONDENSED CONSOLIDATED STATEMENT OF CASH FLOWS - USD ($)
$ in Millions
 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Cash Flows from Operating Activities    
Net income $ 2,457 $ 3,507
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and amortization 2,363 2,355
Intangible asset impairment charges 0 131
Charge for future payments related to Eisai collaboration license options 650 0
Deferred income taxes (258) (272)
Share-based compensation 170 156
Other 429 63
Net changes in assets and liabilities (1,274) (2,337)
Net Cash Provided by Operating Activities 4,537 3,603
Cash Flows from Investing Activities    
Capital expenditures (1,033) (732)
Purchases of securities and other investments (5,248) (6,280)
Proceeds from sales of securities and other investments 7,403 9,363
Other acquisitions, net of cash acquired (372) (347)
Other (274) 62
Net Cash Provided by Investing Activities 476 2,066
Cash Flows from Financing Activities    
Net change in short-term borrowings 2,069 (24)
Payments on debt (3,008) (301)
Purchases of treasury stock (2,162) (2,153)
Dividends paid to stockholders (2,610) (2,601)
Proceeds from exercise of stock options 299 408
Other (277) (86)
Net Cash Used in Financing Activities (5,689) (4,757)
Effect of Exchange Rate Changes on Cash, Cash Equivalents and Restricted Cash (108) 359
Net (Decrease) Increase in Cash, Cash Equivalents and Restricted Cash (784) 1,271
Cash, Cash Equivalents and Restricted Cash at Beginning of Year (includes restricted cash of $4 million at January 1, 2018 included in Other Assets) 6,096 6,515
Cash, Cash Equivalents and Restricted Cash at Beginning of Year (includes restricted cash of $4 million at January 1, 2018 included in Other Assets) $ 5,312 $ 7,786