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Segment Reporting - Sales of Company's Products (Details) - USD ($)
$ in Millions
 3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Segment Reporting Information [Line Items]        
Sales $ 10,465 $ 9,930 $ 20,502 $ 19,365
Proceeds from sale of marketing rights     71 50
Operating Segments        
Segment Reporting Information [Line Items]        
Sales 10,428 9,815 20,496 19,033
Other        
Segment Reporting Information [Line Items]        
Sales 37 115 6 332
United States        
Segment Reporting Information [Line Items]        
Sales 4,243 4,308 8,376 8,503
United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 4,189 4,300 8,296 8,437
United States | Other        
Segment Reporting Information [Line Items]        
Sales 54 8 80 66
International        
Segment Reporting Information [Line Items]        
Sales 6,222 5,623 12,126 10,862
International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 6,240 5,515 12,200 10,596
International | Other        
Segment Reporting Information [Line Items]        
Sales (18) 108 (74) 266
Total Pharmaceutical segment sales | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 9,282 8,759 18,201 16,944
Total Pharmaceutical segment sales | Operating Segments | Keytruda        
Segment Reporting Information [Line Items]        
Sales 1,667 881 3,131 1,465
Total Pharmaceutical segment sales | Operating Segments | Emend        
Segment Reporting Information [Line Items]        
Sales 148 143 273 276
Total Pharmaceutical segment sales | Operating Segments | Temodar        
Segment Reporting Information [Line Items]        
Sales 56 65 113 130
Total Pharmaceutical segment sales | Operating Segments | Alliance revenue - Lynparza        
Segment Reporting Information [Line Items]        
Sales 44 0 76 0
Total Pharmaceutical segment sales | Operating Segments | Alliance revenue - Lenvima        
Segment Reporting Information [Line Items]        
Sales 35 0 35 0
Total Pharmaceutical segment sales | Operating Segments | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 608 469 1,269 1,001
Total Pharmaceutical segment sales | Operating Segments | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 426 399 818 754
Total Pharmaceutical segment sales | Operating Segments | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 193 166 372 329
Total Pharmaceutical segment sales | Operating Segments | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 156 123 349 347
Total Pharmaceutical segment sales | Operating Segments | Zostavax        
Segment Reporting Information [Line Items]        
Sales 44 160 108 313
Total Pharmaceutical segment sales | Operating Segments | Bridion        
Segment Reporting Information [Line Items]        
Sales 240 163 444 310
Total Pharmaceutical segment sales | Operating Segments | Noxafil        
Segment Reporting Information [Line Items]        
Sales 188 155 363 296
Total Pharmaceutical segment sales | Operating Segments | Invanz        
Segment Reporting Information [Line Items]        
Sales 149 150 300 286
Total Pharmaceutical segment sales | Operating Segments | Cubicin        
Segment Reporting Information [Line Items]        
Sales 94 103 192 198
Total Pharmaceutical segment sales | Operating Segments | Cancidas        
Segment Reporting Information [Line Items]        
Sales 87 112 178 233
Total Pharmaceutical segment sales | Operating Segments | Primaxin        
Segment Reporting Information [Line Items]        
Sales 68 71 140 133
Total Pharmaceutical segment sales | Operating Segments | Simponi        
Segment Reporting Information [Line Items]        
Sales 233 199 464 383
Total Pharmaceutical segment sales | Operating Segments | Remicade        
Segment Reporting Information [Line Items]        
Sales 157 208 324 437
Total Pharmaceutical segment sales | Operating Segments | Belsomra        
Segment Reporting Information [Line Items]        
Sales 71 52 125 94
Total Pharmaceutical segment sales | Operating Segments | Isentress/Isentress HD        
Segment Reporting Information [Line Items]        
Sales 305 282 586 587
Total Pharmaceutical segment sales | Operating Segments | Zepatier        
Segment Reporting Information [Line Items]        
Sales 113 517 243 895
Total Pharmaceutical segment sales | Operating Segments | Zetia        
Segment Reporting Information [Line Items]        
Sales 226 367 531 701
Total Pharmaceutical segment sales | Operating Segments | Vytorin        
Segment Reporting Information [Line Items]        
Sales 155 182 322 423
Total Pharmaceutical segment sales | Operating Segments | Atozet        
Segment Reporting Information [Line Items]        
Sales 101 63 174 112
Total Pharmaceutical segment sales | Operating Segments | Adempas        
Segment Reporting Information [Line Items]        
Sales 75 67 143 151
Total Pharmaceutical segment sales | Operating Segments | Januvia        
Segment Reporting Information [Line Items]        
Sales 949 948 1,829 1,787
Total Pharmaceutical segment sales | Operating Segments | Janumet        
Segment Reporting Information [Line Items]        
Sales 585 563 1,129 1,059
Total Pharmaceutical segment sales | Operating Segments | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 236 199 452 359
Total Pharmaceutical segment sales | Operating Segments | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 174 178 348 349
Total Pharmaceutical segment sales | Operating Segments | Singulair        
Segment Reporting Information [Line Items]        
Sales 185 203 360 389
Total Pharmaceutical segment sales | Operating Segments | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 125 119 245 231
Total Pharmaceutical segment sales | Operating Segments | Nasonex        
Segment Reporting Information [Line Items]        
Sales 81 85 203 224
Total Pharmaceutical segment sales | Operating Segments | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 84 89 166 192
Total Pharmaceutical segment sales | Operating Segments | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 70 79 138 160
Total Pharmaceutical segment sales | Operating Segments | Fosamax        
Segment Reporting Information [Line Items]        
Sales 59 66 114 127
Total Pharmaceutical segment sales | Operating Segments | Dulera        
Segment Reporting Information [Line Items]        
Sales 42 69 99 151
Total Pharmaceutical segment sales | Operating Segments | Other Pharmaceutical        
Segment Reporting Information [Line Items]        
Sales 1,053 1,064 2,045 2,062
Total Pharmaceutical segment sales | United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 3,822 3,929 7,538 7,690
Total Pharmaceutical segment sales | United States | Operating Segments | Keytruda        
Segment Reporting Information [Line Items]        
Sales 959 556 1,797 917
Total Pharmaceutical segment sales | United States | Operating Segments | Emend        
Segment Reporting Information [Line Items]        
Sales 89 83 168 169
Total Pharmaceutical segment sales | United States | Operating Segments | Temodar        
Segment Reporting Information [Line Items]        
Sales 1 3 2 4
Total Pharmaceutical segment sales | United States | Operating Segments | Alliance revenue - Lynparza        
Segment Reporting Information [Line Items]        
Sales 31 0 55 0
Total Pharmaceutical segment sales | United States | Operating Segments | Alliance revenue - Lenvima        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 302 312 682 711
Total Pharmaceutical segment sales | United States | Operating Segments | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 356 341 668 639
Total Pharmaceutical segment sales | United States | Operating Segments | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 122 104 234 219
Total Pharmaceutical segment sales | United States | Operating Segments | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 99 72 250 251
Total Pharmaceutical segment sales | United States | Operating Segments | Zostavax        
Segment Reporting Information [Line Items]        
Sales 1 107 17 216
Total Pharmaceutical segment sales | United States | Operating Segments | Bridion        
Segment Reporting Information [Line Items]        
Sales 95 54 175 99
Total Pharmaceutical segment sales | United States | Operating Segments | Noxafil        
Segment Reporting Information [Line Items]        
Sales 87 77 168 142
Total Pharmaceutical segment sales | United States | Operating Segments | Invanz        
Segment Reporting Information [Line Items]        
Sales 87 93 177 175
Total Pharmaceutical segment sales | United States | Operating Segments | Cubicin        
Segment Reporting Information [Line Items]        
Sales 48 53 95 107
Total Pharmaceutical segment sales | United States | Operating Segments | Cancidas        
Segment Reporting Information [Line Items]        
Sales 4 6 7 11
Total Pharmaceutical segment sales | United States | Operating Segments | Primaxin        
Segment Reporting Information [Line Items]        
Sales 0 1 5 2
Total Pharmaceutical segment sales | United States | Operating Segments | Simponi        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Remicade        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Belsomra        
Segment Reporting Information [Line Items]        
Sales 29 25 52 45
Total Pharmaceutical segment sales | United States | Operating Segments | Isentress/Isentress HD        
Segment Reporting Information [Line Items]        
Sales 132 136 260 279
Total Pharmaceutical segment sales | United States | Operating Segments | Zepatier        
Segment Reporting Information [Line Items]        
Sales (10) 256 (10) 455
Total Pharmaceutical segment sales | United States | Operating Segments | Zetia        
Segment Reporting Information [Line Items]        
Sales 8 122 25 233
Total Pharmaceutical segment sales | United States | Operating Segments | Vytorin        
Segment Reporting Information [Line Items]        
Sales 3 30 11 120
Total Pharmaceutical segment sales | United States | Operating Segments | Atozet        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Adempas        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Januvia        
Segment Reporting Information [Line Items]        
Sales 503 541 968 1,048
Total Pharmaceutical segment sales | United States | Operating Segments | Janumet        
Segment Reporting Information [Line Items]        
Sales 209 248 401 442
Total Pharmaceutical segment sales | United States | Operating Segments | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 187 153 357 265
Total Pharmaceutical segment sales | United States | Operating Segments | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 114 125 242 257
Total Pharmaceutical segment sales | United States | Operating Segments | Singulair        
Segment Reporting Information [Line Items]        
Sales 5 6 11 12
Total Pharmaceutical segment sales | United States | Operating Segments | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 7 3 14 6
Total Pharmaceutical segment sales | United States | Operating Segments | Nasonex        
Segment Reporting Information [Line Items]        
Sales 0 21 2 39
Total Pharmaceutical segment sales | United States | Operating Segments | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 0 0 0 0
Total Pharmaceutical segment sales | United States | Operating Segments | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 27 32 56 74
Total Pharmaceutical segment sales | United States | Operating Segments | Fosamax        
Segment Reporting Information [Line Items]        
Sales 3 2 1 3
Total Pharmaceutical segment sales | United States | Operating Segments | Dulera        
Segment Reporting Information [Line Items]        
Sales 35 63 85 139
Total Pharmaceutical segment sales | United States | Operating Segments | Other Pharmaceutical        
Segment Reporting Information [Line Items]        
Sales 289 304 563 611
Total Pharmaceutical segment sales | International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 5,461 4,830 10,663 9,255
Total Pharmaceutical segment sales | International | Operating Segments | Keytruda        
Segment Reporting Information [Line Items]        
Sales 707 325 1,333 547
Total Pharmaceutical segment sales | International | Operating Segments | Emend        
Segment Reporting Information [Line Items]        
Sales 59 60 105 107
Total Pharmaceutical segment sales | International | Operating Segments | Temodar        
Segment Reporting Information [Line Items]        
Sales 54 61 111 126
Total Pharmaceutical segment sales | International | Operating Segments | Alliance revenue - Lynparza        
Segment Reporting Information [Line Items]        
Sales 13 0 22 0
Total Pharmaceutical segment sales | International | Operating Segments | Alliance revenue - Lenvima        
Segment Reporting Information [Line Items]        
Sales 35 0 35 0
Total Pharmaceutical segment sales | International | Operating Segments | Gardasil/Gardasil 9        
Segment Reporting Information [Line Items]        
Sales 306 156 586 290
Total Pharmaceutical segment sales | International | Operating Segments | ProQuad/M-M-R II/Varivax        
Segment Reporting Information [Line Items]        
Sales 70 58 150 115
Total Pharmaceutical segment sales | International | Operating Segments | Pneumovax 23        
Segment Reporting Information [Line Items]        
Sales 71 61 137 110
Total Pharmaceutical segment sales | International | Operating Segments | RotaTeq        
Segment Reporting Information [Line Items]        
Sales 57 51 99 96
Total Pharmaceutical segment sales | International | Operating Segments | Zostavax        
Segment Reporting Information [Line Items]        
Sales 43 52 91 97
Total Pharmaceutical segment sales | International | Operating Segments | Bridion        
Segment Reporting Information [Line Items]        
Sales 145 109 269 211
Total Pharmaceutical segment sales | International | Operating Segments | Noxafil        
Segment Reporting Information [Line Items]        
Sales 100 78 195 154
Total Pharmaceutical segment sales | International | Operating Segments | Invanz        
Segment Reporting Information [Line Items]        
Sales 63 57 123 111
Total Pharmaceutical segment sales | International | Operating Segments | Cubicin        
Segment Reporting Information [Line Items]        
Sales 46 50 97 92
Total Pharmaceutical segment sales | International | Operating Segments | Cancidas        
Segment Reporting Information [Line Items]        
Sales 83 106 171 222
Total Pharmaceutical segment sales | International | Operating Segments | Primaxin        
Segment Reporting Information [Line Items]        
Sales 68 70 135 132
Total Pharmaceutical segment sales | International | Operating Segments | Simponi        
Segment Reporting Information [Line Items]        
Sales 233 199 464 383
Total Pharmaceutical segment sales | International | Operating Segments | Remicade        
Segment Reporting Information [Line Items]        
Sales 157 208 324 437
Total Pharmaceutical segment sales | International | Operating Segments | Belsomra        
Segment Reporting Information [Line Items]        
Sales 42 28 73 49
Total Pharmaceutical segment sales | International | Operating Segments | Isentress/Isentress HD        
Segment Reporting Information [Line Items]        
Sales 174 146 326 308
Total Pharmaceutical segment sales | International | Operating Segments | Zepatier        
Segment Reporting Information [Line Items]        
Sales 123 261 253 440
Total Pharmaceutical segment sales | International | Operating Segments | Zetia        
Segment Reporting Information [Line Items]        
Sales 218 246 505 468
Total Pharmaceutical segment sales | International | Operating Segments | Vytorin        
Segment Reporting Information [Line Items]        
Sales 152 152 311 303
Total Pharmaceutical segment sales | International | Operating Segments | Atozet        
Segment Reporting Information [Line Items]        
Sales 101 63 174 112
Total Pharmaceutical segment sales | International | Operating Segments | Adempas        
Segment Reporting Information [Line Items]        
Sales 75 67 143 151
Total Pharmaceutical segment sales | International | Operating Segments | Januvia        
Segment Reporting Information [Line Items]        
Sales 446 407 862 740
Total Pharmaceutical segment sales | International | Operating Segments | Janumet        
Segment Reporting Information [Line Items]        
Sales 377 315 729 617
Total Pharmaceutical segment sales | International | Operating Segments | NuvaRing        
Segment Reporting Information [Line Items]        
Sales 49 47 95 94
Total Pharmaceutical segment sales | International | Operating Segments | Implanon/Nexplanon        
Segment Reporting Information [Line Items]        
Sales 60 53 106 92
Total Pharmaceutical segment sales | International | Operating Segments | Singulair        
Segment Reporting Information [Line Items]        
Sales 180 197 350 377
Total Pharmaceutical segment sales | International | Operating Segments | Cozaar/Hyzaar        
Segment Reporting Information [Line Items]        
Sales 118 116 231 226
Total Pharmaceutical segment sales | International | Operating Segments | Nasonex        
Segment Reporting Information [Line Items]        
Sales 81 64 201 185
Total Pharmaceutical segment sales | International | Operating Segments | Arcoxia        
Segment Reporting Information [Line Items]        
Sales 84 89 166 192
Total Pharmaceutical segment sales | International | Operating Segments | Follistim AQ        
Segment Reporting Information [Line Items]        
Sales 43 47 81 86
Total Pharmaceutical segment sales | International | Operating Segments | Fosamax        
Segment Reporting Information [Line Items]        
Sales 56 65 113 124
Total Pharmaceutical segment sales | International | Operating Segments | Dulera        
Segment Reporting Information [Line Items]        
Sales 7 5 14 12
Total Pharmaceutical segment sales | International | Operating Segments | Other Pharmaceutical        
Segment Reporting Information [Line Items]        
Sales 765 761 1,483 1,449
Total Animal Health segment sales | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 1,090 955 2,155 1,894
Total Animal Health segment sales | Operating Segments | Livestock        
Segment Reporting Information [Line Items]        
Sales 633 582 1,286 1,161
Total Animal Health segment sales | Operating Segments | Companion Animals        
Segment Reporting Information [Line Items]        
Sales 457 373 869 733
Total Animal Health segment sales | United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 311 270 618 553
Total Animal Health segment sales | United States | Operating Segments | Livestock        
Segment Reporting Information [Line Items]        
Sales 107 103 231 223
Total Animal Health segment sales | United States | Operating Segments | Companion Animals        
Segment Reporting Information [Line Items]        
Sales 204 167 387 330
Total Animal Health segment sales | International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 779 685 1,537 1,341
Total Animal Health segment sales | International | Operating Segments | Livestock        
Segment Reporting Information [Line Items]        
Sales 526 479 1,055 938
Total Animal Health segment sales | International | Operating Segments | Companion Animals        
Segment Reporting Information [Line Items]        
Sales 253 206 482 403
Other segment sales | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 56 101 140 195
Other segment sales | United States | Operating Segments        
Segment Reporting Information [Line Items]        
Sales 56 101 140 194
Other segment sales | International | Operating Segments        
Segment Reporting Information [Line Items]        
Sales $ 0 $ 0 $ 0 $ 0