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Collaborative Arrangements - Schedule of Collaborative Arrangement Transactions (Details) - Collaborative Arrangement - USD ($) $ in Millions | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2018 | Sep. 30, 2017 | Sep. 30, 2018 | Sep. 30, 2017 | Dec. 31, 2017
AstraZeneca |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Receivables from counterparty | $ 46 |  | $ 46 |  | $ 12
Payables to counterparty | 892 |  | 892 |  | 643
AstraZeneca | Revenue |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Total sales | 49 | $ 5 | 125 | $ 5 |
AstraZeneca | Materials and production |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 12 | 0 | 48 | 0 |
AstraZeneca | Marketing and administrative |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 12 | 0 | 28 | 0 |
AstraZeneca | Research and development |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 47 | 2,377 | 118 | 2,377 |
Eisai |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Receivables from counterparty | 42 |  | 42 |  |
Payables to counterparty | 733 |  | 733 |  |
Eisai | Revenue |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Total sales | 43 |  | 78 |  |
Eisai | Materials and production |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 8 |  | 9 |  |
Eisai | Marketing and administrative |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 5 |  | 7 |  |
Eisai | Research and development |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 36 |  | 1,473 |  |
Bayer AG |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Receivables from counterparty | 36 |  | 36 |  | 33
Payables to counterparty | 375 |  | 375 |  | $ 352
Bayer AG | Revenue |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Net product sales recorded by Merck | 47 | 38 | 138 | 105 |
Merck’s profit share from sales in Bayer’s marketing territories | 47 | 32 | 100 | 116 |
Total sales | 94 | 70 | 238 | 221 |
Bayer AG | Materials and production |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 29 | 25 | 188 | 73 |
Bayer AG | Marketing and administrative |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | 11 | 6 | 26 | 18 |
Bayer AG | Research and development |  |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |  |
Expenses | $ 34 | $ 27 | $ 90 | $ 78 |

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