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Taxes on Income - Narrative (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Dec. 31, 2017
Income Tax Examination [Line Items]          
Effective income tax rate (as percent) 26.50% 125.50% 27.60% 25.50%  
Aggregate charge related to termination of collaboration agreement with Samsung     $ 420 $ 0  
Materials and production $ 3,619 $ 3,307 10,220 9,472  
Research and development 2,068 4,413 7,538 8,024  
Tax benefit related to settlement of state income tax issue       (88)  
Provisional transition tax liability         $ 5,300
Provisional net transition tax payment         5,100
Provisional deferred tax benefit         779
2017 Tax Cuts and Jobs Act (TCJA)          
Income Tax Examination [Line Items]          
Deferred taxes         2,000
Internal Revenue Service (IRS)          
Income Tax Examination [Line Items]          
Net tax benefit related to settlement of certain federal income tax issues   234   234  
Income taxes paid   2,800   2,800  
Samsung          
Income Tax Examination [Line Items]          
Aggregate charge related to termination of collaboration agreement with Samsung $ 420   420    
Eisai          
Income Tax Examination [Line Items]          
Research and development     $ 1,400    
AstraZeneca          
Income Tax Examination [Line Items]          
Research and development   $ 2,350   $ 2,350 $ 2,350