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Acquisitions, Research Collaborations and License Agreements - Acquisitions (Details) - Subsequent Event $ in Millions	1 Months Ended
	Apr. 30, 2019 USD ($)
Antelliq
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]
Payment to acquire business	$ 2,300
Payment of debt	1,300
Immune Design
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]
Payment to acquire business	$ 301

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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- Definition

The cash outflow associated with the acquisition of business during the period. The cash portion only of the acquisition price.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 30
-Section 50
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The cash outflow during the period from the repayment of aggregate short-term and long-term debt. Excludes payment of capital lease obligations.

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-Publisher FASB
-Name Accounting Standards Codification
-Topic 230
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-Section 45
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