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Financial Instruments - Narrative (Details) | 6 Months Ended |
--- | --- | ---
Jun. 30, 2019 USD ($) interest_rate_swap | Jun. 30, 2018 USD ($) | Dec. 31, 2018 USD ($)
Derivative [Line Items] |  |  |
Number of interest rate swaps held (in interest rate swaps) | interest_rate_swap | 19 |  |
Pretax net unrealized gain on derivatives maturing within next 12 months estimated to be reclassified from AOCI to sales | $ 76,000,000 |  |
Equity investments without readily determinable fair values | 465,000,000 |  |
Unrealized gains recognized on investments in equity securities without readily determinable fair values | 4,000,000 |  |
Unrealized losses recognized on investments in equity securities without readily determinable fair values | 10,000,000 |  |
Cumulative unrealized gains on investments | 172,000,000 |  |
Cumulative unrealized losses on investments | 21,000,000 |  |
Available-for-sale debt securities included in Short-term investments | 398,000,000 |  |
Available-for-sale debt securities maturing after one year through five years | 3,400,000,000 |  |
Cash and cash equivalents | 6,659,000,000 |  | $ 7,965,000,000
Payments of contingent consideration | 85,000,000 | $ 235,000,000 |
Fair value of loans payable and long-term debt, including current portion | 28,600,000,000 |  | 25,600,000,000
Debt, Long-term and Short-term, Combined Amount | 26,600,000,000 |  | 25,100,000,000
Cash collateral received from counterparties | 32,000,000 |  | 107,000,000
Cash collateral advanced to counterparties | 0 |  | $ 0
Significant Other Observable Inputs (Level 2) |  |  |
Derivative [Line Items] |  |  |
Cash and cash equivalents | 6,700,000,000 |  |
Cash equivalents | $ 5,900,000,000 |  |
Derivatives Designated as Hedging Instruments | Maximum |  |  |
Derivative [Line Items] |  |  |
Maximum average period of maturities of contracts in years (less than) | 2 years |  |
Derivatives Not Designated as Hedging Instruments | Maximum |  |  |
Derivative [Line Items] |  |  |
Maximum average period of maturities of contracts in years (less than) | 1 year |  |
gefapixant |  |  |
Derivative [Line Items] |  |  |
Payments of contingent consideration |  | $ 175,000,000 |

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