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CONDENSED CONSOLIDATED STATEMENT OF CASH FLOWS - USD ($)
$ in Millions
 6 Months Ended
Jun. 30, 2019
Jun. 30, 2018
Cash Flows from Operating Activities    
Net income $ 5,506 $ 2,457
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation and amortization 1,871 2,427
Intangible asset impairment charges 252 0
Charge for future payments related to collaboration license options 0 650
Deferred income taxes (149) (258)
Share-based compensation 204 170
Other 114 365
Net changes in assets and liabilities (3,378) (1,274)
Net Cash Provided by Operating Activities 4,420 4,537
Cash Flows from Investing Activities    
Capital expenditures (1,377) (1,033)
Purchases of securities and other investments (1,810) (5,248)
Proceeds from sales of securities and other investments 4,935 7,403
Acquisition of Antelliq Corporation, net of cash acquired (3,620) 0
Other acquisitions, net of cash acquired (270) (372)
Other 85 (274)
Net Cash (Used in) Provided by Investing Activities (2,057) 476
Cash Flows from Financing Activities    
Net change in short-term borrowings (3,532) 2,069
Payments on debt 0 (3,008)
Proceeds from issuance of debt 4,958 0
Purchases of treasury stock (2,325) (2,162)
Dividends paid to stockholders (2,896) (2,610)
Proceeds from exercise of stock options 304 299
Other (207) (277)
Net Cash Used in Financing Activities (3,698) (5,689)
Effect of Exchange Rate Changes on Cash, Cash Equivalents and Restricted Cash 28 (108)
Net Decrease in Cash, Cash Equivalents and Restricted Cash (1,307) (784)
Cash, Cash Equivalents and Restricted Cash at Beginning of Year (includes restricted cash of $2 million at January 1, 2019 included in Other Assets) 7,967 6,096
Cash, Cash Equivalents and Restricted Cash at End of Period (includes restricted cash of $1 million at June 30, 2019 included in Other Assets) $ 6,660 $ 5,312