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Segment Reporting - Profits to Income Before Taxes (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2020
Mar. 31, 2019
Segment Reporting Information [Line Items]    
Profits $ 3,838 $ 3,067
Interest income 25 89
Interest expense (212) (209)
Depreciation and amortization (821) (898)
Research and development (2,209) (1,931)
Restructuring costs (72) (153)
Total segment profits    
Segment Reporting Information [Line Items]    
Profits 7,956 6,991
Total segment profits | Pharmaceutical segment    
Segment Reporting Information [Line Items]    
Profits 7,477 6,574
Total segment profits | Animal Health segment    
Segment Reporting Information [Line Items]    
Profits 478 415
Total segment profits | Other segment    
Segment Reporting Information [Line Items]    
Profits 1 2
Other profits    
Segment Reporting Information [Line Items]    
Profits 139 30
Unallocated    
Segment Reporting Information [Line Items]    
Interest income 25 89
Interest expense (212) (209)
Depreciation and amortization (381) (359)
Research and development (2,097) (1,843)
Amortization of purchase accounting adjustments (295) (397)
Restructuring costs (72) (153)
Other unallocated, net $ (1,225) $ (1,082)