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Taxes on Income - Reconciliation Between Effective Tax Rate and US Statutory Rate (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Amount      
U.S. statutory rate applied to income before taxes $ 1,846 $ 2,408 $ 1,827
Differential arising from:      
Foreign earnings (1,242) (1,020) (245)
GILTI and the foreign-derived intangible income deduction 364 336 (25)
R&D tax credit (110) (118) (96)
Valuation allowances 42 113 269
Tax settlements (13) (403) (22)
Acquisition of VelosBio 559 0 0
Restructuring 105 39 56
Acquisition of OncoImmune 97 0 0
State taxes 67 (2) 201
Acquisition-related costs, including amortization 46 95 267
Acquisition of Peloton 0 209 0
Tax Cuts and Jobs Act of 2017 0 117 289
Other (52) (87) (13)
Taxes on income $ 1,709 $ 1,687 $ 2,508
Tax Rate      
U.S. statutory rate applied to income before taxes 21.00% 21.00% 21.00%
Differential arising from:      
Foreign earnings (14.10%) (8.90%) (2.80%)
GILTI and the foreign-derived intangible income deduction 4.10% 2.90% (0.30%)
R&D tax credit (1.30%) (1.00%) (1.10%)
Valuation allowances 0.50% 1.00% 3.10%
Tax settlements (0.20%) (3.50%) (0.30%)
Acquisition of VelosBio 6.30% 0.00% 0.00%
Restructuring 1.20% 0.30% 0.60%
Acquisition of OncoImmune 1.10% 0.00% 0.00%
State taxes 0.80% 0.00% 2.30%
Acquisition-related costs, including amortization 0.50% 0.80% 3.10%
Acquisition of Peloton 0.00% 1.80% 0.00%
Tax Cuts and Jobs Act of 2017 0 0.010 0.033
Other (0.50%) (0.70%) (0.10%)
Total, Tax Rate 19.40% 14.70% 28.80%