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Collaborative Arrangements - Narrative (Details) - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 12 Months Ended | 37 Months Ended
--- | --- | --- | --- | ---
Mar. 31, 2021 | Mar. 31, 2020 | Mar. 31, 2019 | Mar. 31, 2018 | Mar. 31, 2021 | Mar. 31, 2020 | Dec. 31, 2020 | Mar. 31, 2021
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Research and development |  |  |  |  | $ 2,465 | $ 2,209 |  |
Other liabilities, noncurrent | $ 12,241 |  |  |  | 12,241 |  | $ 12,482 | $ 12,241
Amortization |  |  |  |  | 534 | $ 410 |  |
Lynparza | Other Assets |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Finite-lived intangible assets | 1,200 |  |  |  | 1,200 |  |  | 1,200
Lenvima | Other Assets |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Finite-lived intangible assets | 1,000 |  |  |  | 1,000 |  |  | 1,000
Adempas | Other intangible assets |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Finite-lived intangible assets | 946 |  |  |  | 946 |  |  | 946
Verquvo |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Amortization |  |  |  |  | 153 |  |  |
Verquvo | Other intangible assets |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Finite-lived intangible assets | 76 |  |  |  | 76 |  |  | 76
AstraZeneca | Regulatory Milestones | Lynparza |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Potential Future Milestone Payments Regulatory | 1,400 |  |  |  | 1,400 |  |  | 1,400
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Potential Future Milestone Payments Sales-Based | 2,700 |  |  |  | 2,700 |  |  | 2,700
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lynparza |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Milestone Payments Sales-Based |  |  |  |  |  |  | 1,000 |
Milestone Payments Accrued Sales Based |  |  |  |  |  |  | 1,400 |
Milestone Payments Made Regulatory |  |  |  |  |  |  | 360 |
Eisai |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Upfront and milestone payments |  |  |  | $ 750 |  |  |  |
License option payment related to collaborative arrangement | 125 | $ 200 | $ 325 |  |  |  |  | 650
Eisai | Sales-Based Milestones |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Potential Future Milestone Payments Sales-Based | 2,600 |  |  |  | 2,600 |  |  | 2,600
Eisai | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lenvima |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Milestone Payments Sales-Based |  |  |  |  | 200 |  | 550 |
Milestone Payments Accrued Sales Based |  |  |  |  |  |  | 1,350 |
Milestone Payments Made Regulatory |  |  |  |  |  |  | 260 |
Potential Future Milestone Payments Regulatory | 125 |  |  |  | 125 |  |  | 125
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |  |  |
Liabilities | 400 |  |  |  | 400 |  |  | 400
Milestone Payments Sales-Based |  |  |  |  |  |  | $ 725 |
Milestone Payments Accrued Sales Based | $ 400 |  |  |  | $ 400 |  |  | $ 400

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