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Acquisitions, Research Collaborations and License Agreements - Acquisitions (Details) - USD ($) $ in Millions |  | 1 Months Ended | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Jan. 16, 2020 | Apr. 30, 2021 | Jan. 31, 2021 | Dec. 31, 2020 | Mar. 31, 2021 | Mar. 31, 2020 | Dec. 31, 2020 | Dec. 31, 2019
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent consideration |  |  |  | $ 841.0 | $ 816.0 | $ 694.0 | $ 841.0 | $ 767.0
Goodwill |  |  |  | 20,238.0 | 20,212.0 |  | 20,238.0 |
Research and development |  |  |  |  | 2,465.0 | 2,209.0 |  |
Inventories |  |  |  | 6,310.0 | 6,402.0 |  | 6,310.0 |
Payments to Acquire Productive Assets |  |  |  |  | 1,134.0 | $ 986.0 |  |
COVID-19 |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Charges related to program discontinuation |  |  |  |  | $ 170.0 |  |  |
ArQule |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Payment to acquire business | $ 2,700.0 |  |  |  |  |  |  |
IPR&D | 2,280.0 |  |  |  |  |  |  |
Share-based compensation payments attributable to precombination service | 138.0 |  |  |  |  |  |  |
Transaction costs | 95.0 |  |  |  |  |  |  |
Cash and cash equivalents | 145.0 |  |  |  |  |  |  |
Goodwill | 512.0 |  |  |  |  |  |  |
Other assets and liabilities, net | 34.0 |  |  |  |  |  |  |
Deferred income tax liabilities | 361.0 |  |  |  |  |  |  |
Intangible assets | $ 80.0 |  |  |  |  |  |  |
OncoImmune |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Payment to acquire business |  |  |  | 423.0 |  |  |  |
Other assets and liabilities, net |  |  |  | (22.0) |  |  | $ (22.0) |
Payments to Acquire Investments |  |  |  | $ 50.0 |  |  |  |
Equity Method Investment, Ownership Percentage |  |  |  | 20.00% |  |  | 20.00% |
Investments |  |  |  | $ 33.0 |  |  | $ 33.0 |
Premium on shares acquired |  |  |  | $ 17.0 |  |  |  |
Research and Development Asset Acquired Other than Through Business Combination, Written-off |  |  |  |  |  |  | $ 462.0 |
Pandion Therapeutics | Subsequent Event |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Payment to acquire business |  | $ 1,850.0 |  |  |  |  |  |
Gilead Sciences | oral and injectable formulations programs | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
proft share |  |  |  |  | 40.00% |  |  |
profit share counterparty |  |  |  |  | 60.00% |  |  |
Gilead Sciences | oral formulation | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
proft share |  |  |  |  | 35.00% |  |  |
profit share counterparty |  |  |  |  | 65.00% |  |  |
Sales threshold |  |  |  |  | $ 2,000.0 |  |  |
Gilead Sciences | injectable formulation | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
proft share |  |  |  |  | 35.00% |  |  |
profit share counterparty |  |  |  |  | 65.00% |  |  |
Sales threshold |  |  |  |  | $ 3,500.0 |  |  |
Artiva Biotherapeutics, Inc. | Licensing Agreements |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Upfront and milestone payments |  |  | $ 30.0 |  |  |  |  |
Upfront and milestone payments to be made |  |  | $ 15.0 |  |  |  |  |
Artiva Biotherapeutics, Inc. | Minimum | Licensing Agreements |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Royalty Rate, Percentage |  |  | 7.00% |  |  |  |  |
Artiva Biotherapeutics, Inc. | Maximum | Licensing Agreements |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Royalty Rate, Percentage |  |  | 14.00% |  |  |  |  |
Artiva Biotherapeutics, Inc. | Development Milestones | Licensing Agreements |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  | $ 217.5 |  |  |  |  |
Artiva Biotherapeutics, Inc. | Sales-Based Milestones | Licensing Agreements |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  | 1,050.0 |  |  |  |  |
Artiva Biotherapeutics, Inc. | Regulatory Milestones | Licensing Agreements |  |  |  |  |  |  |  |
Acquisitions Research Collaborations And License Agreements Transactions [Line Items] |  |  |  |  |  |  |  |
Contingent milestone payments collaborative arrangement |  |  | $ 570.0 |  |  |  |  |

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