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Collaborative Arrangements - Narrative (Details) - USD ($) $ in Millions | 1 Months Ended | 3 Months Ended | 6 Months Ended |
--- | --- | --- | --- | ---
Mar. 31, 2021 | Jun. 30, 2021 | Jun. 30, 2020 | Jun. 30, 2021 | Jun. 30, 2020 | Dec. 31, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Research and development |  | $ 4,321 | $ 2,085 | $ 6,732 | $ 4,260 |
Other liabilities, noncurrent |  | 9,872 |  | 9,872 |  | $ 12,306
Amortization |  |  |  | 871 | $ 988 |
Lynparza | Other Assets |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Finite-lived intangible assets |  | 1,200 |  | 1,200 |  |
Lenvima | Other Assets |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Finite-lived intangible assets |  | 1,000 |  | 1,000 |  |
Adempas | Other intangible assets |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Finite-lived intangible assets |  | 920 |  | 920 |  |
Verquvo |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Amortization |  |  |  | 153 |  |
Verquvo | Other intangible assets |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Finite-lived intangible assets |  | 75 |  | 75 |  |
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lynparza |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Potential Future Milestone Payments Sales-Based |  | 2,700 |  | 2,700 |  |
Milestone Payments Accrued Sales Based |  | 400 |  | 400 |  |
Potential Future Milestone Payments Regulatory |  | 1,400 |  | 1,400 |  |
Eisai |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
License option payment related to collaborative arrangement | $ 125 |  |  |  |  |
Eisai | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lenvima |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Potential Future Milestone Payments Sales-Based |  | 2,600 |  | 2,600 |  |
Milestone Payments Sales-Based |  |  |  | 200 |  |
Milestone Payments Accrued Sales Based |  | 600 |  | 600 |  |
Potential Future Milestone Payments Regulatory |  | 125 |  | 125 |  |
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement |  |  |  |  |  |
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] |  |  |  |  |  |
Liabilities |  | 400 |  | 400 |  |
Milestone Payments Accrued Sales Based |  | $ 400 |  | $ 400 |  |

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