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Acquisitions, Research Collaborations and License Agreements - Acquisitions (Details) - USD ($)
$ in Millions
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jan. 16, 2020
Apr. 30, 2021
Mar. 31, 2021
Jan. 31, 2021
Dec. 31, 2020
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Dec. 31, 2020
Dec. 31, 2019
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Contingent consideration         $ 841.0 $ 798.0 $ 879.0 $ 798.0 $ 879.0 $ 798.0 $ 841.0 $ 767.0
Goodwill         18,882.0   18,873.0   18,873.0   18,882.0  
Research and development             4,321.0 2,085.0 6,732.0 4,260.0    
Inventories         5,554.0   5,499.0   5,499.0   5,554.0  
Payments to Acquire Productive Assets                 2,068.0 1,553.0    
Changes in estimated fair value                 50.0 40.0    
OncoImmune                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Payment to acquire business         423.0              
Other assets and liabilities, net         (22.0)           $ (22.0)  
Payments to Acquire Investments         $ 50.0              
Equity Method Investment, Ownership Percentage         20.00%           20.00%  
Investments         $ 33.0           $ 33.0  
Premium on shares acquired         $ 17.0              
Research and Development Asset Acquired Other than Through Business Combination, Written-off                     462.0  
COVID-19                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Charges related to program discontinuation             $ 37.0   $ 207.0      
Pandion Therapeutics                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Payment to acquire business   $ 1,900.0                    
Transaction costs   147.0                    
Other assets and liabilities, net   (156.0)                    
Research and development   $ 1,700.0                    
Themis                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Payment to acquire business           366.0            
Contingent consideration           85.0   85.0   85.0    
IPR&D           113.0   113.0   113.0    
Cash and cash equivalents           59.0   59.0   59.0    
Goodwill           239.0   239.0   239.0    
Other assets and liabilities, net           (32.0)   (32.0)   (32.0)    
Deferred tax assets           72.0   72.0   72.0    
Contingent consideration, maximum           740.0   740.0   740.0    
Business Combination, Contingent Consideration Arrangements, Change in Range of Outcomes, Contingent Consideration, Liability, Value, High                     450.0  
Themis | COVID-19                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Impairment of Intangible Assets, Indefinite-lived (Excluding Goodwill)                     90.0  
Changes in estimated fair value                     $ 45.0  
ArQule                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Payment to acquire business $ 2,700.0                      
IPR&D 2,280.0                      
Share-based compensation payments attributable to precombination service 138.0                      
Transaction costs 95.0                      
Cash and cash equivalents 145.0                      
Goodwill 512.0                      
Other assets and liabilities, net 34.0                      
Deferred income tax liabilities 361.0                      
Intangible assets $ 80.0                      
Development Milestones | Themis                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Contingent consideration, maximum           60.0   60.0   60.0    
Sales-Based Milestones | Themis                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Contingent consideration, maximum           194.0   194.0   194.0    
Regulatory Milestones | Themis                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Contingent consideration, maximum           $ 196.0   $ 196.0   $ 196.0    
Gilead Sciences | oral and injectable formulations programs | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
proft share     40.00%                  
profit share counterparty     60.00%                  
Gilead Sciences | oral formulation | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
proft share     35.00%                  
profit share counterparty     65.00%                  
Sales threshold     $ 2,000.0                  
Gilead Sciences | injectable formulation | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
proft share     35.00%                  
profit share counterparty     65.00%                  
Sales threshold     $ 3,500.0                  
Artiva Biotherapeutics, Inc. | Licensing Agreements                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Upfront and milestone payments       $ 30.0                
Upfront and milestone payments to be made       $ 15.0                
Artiva Biotherapeutics, Inc. | Minimum | Licensing Agreements                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Royalty Rate, Percentage       7.00%                
Artiva Biotherapeutics, Inc. | Maximum | Licensing Agreements                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Royalty Rate, Percentage       14.00%                
Artiva Biotherapeutics, Inc. | Development Milestones | Licensing Agreements                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Contingent milestone payments collaborative arrangement       $ 217.5                
Artiva Biotherapeutics, Inc. | Sales-Based Milestones | Licensing Agreements                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Contingent milestone payments collaborative arrangement       1,050.0                
Artiva Biotherapeutics, Inc. | Regulatory Milestones | Licensing Agreements                        
Acquisitions Research Collaborations And License Agreements Transactions [Line Items]                        
Contingent milestone payments collaborative arrangement       $ 570.0