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Segment Reporting - Profits to Income Before Taxes (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2021
Jun. 30, 2020
Jun. 30, 2021
Jun. 30, 2020
Segment Reporting Information [Line Items]        
Profits $ 1,717 $ 2,741 $ 4,704 $ 5,702
Interest income 9 14 20 39
Interest expense (202) (209) (401) (421)
Amortization     871 988
Research and development (4,321) (2,085) (6,732) (4,260)
Restructuring costs (82) (82) (380) (152)
Total segment profits        
Segment Reporting Information [Line Items]        
Profits 7,809 6,240 14,969 13,098
Total segment profits | Pharmaceutical segment        
Segment Reporting Information [Line Items]        
Profits 7,257 5,832 13,845 12,209
Total segment profits | Animal Health segment        
Segment Reporting Information [Line Items]        
Profits 552 408 1,124 887
Total segment profits | Other segment        
Segment Reporting Information [Line Items]        
Profits 0 0 0 2
Other profits        
Segment Reporting Information [Line Items]        
Profits (79) 43 (113) 163
Unallocated        
Segment Reporting Information [Line Items]        
Interest income 9 14 20 39
Interest expense (202) (209) (401) (421)
Amortization 357 599 871 988
Depreciation (332) (367) (673) (733)
Research and development (4,175) (1,956) (6,480) (4,020)
Restructuring costs (82) (82) (380) (152)
Other unallocated, net $ (874) $ (343) $ (1,367) $ (1,284)