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Collaborative Arrangements - Narrative (Details) - USD ($) $ in Millions	1 Months Ended	3 Months Ended	9 Months Ended
	Mar. 31, 2021	Sep. 30, 2021	Sep. 30, 2021	Sep. 30, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Amortization			$ 1,231	$ 1,393
Lynparza | Other Noncurrent Assets
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Finite-lived intangible assets		$ 1,100	1,100
Lenvima | Other Noncurrent Assets
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Finite-lived intangible assets		1,000	1,000
Verquvo
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Amortization			153
Verquvo | Other Intangible Assets
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Finite-lived intangible assets		72	72
Adempas | Other Intangible Assets
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Finite-lived intangible assets		869	869
AstraZeneca | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lynparza
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payments accrued but not yet paid		400	400
Potential future sales-based milestone payments		2,700	2,700
Potential future regulatory milestone payments		1,400	1,400
Eisai
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
License option payment related to collaborative arrangement	$ 125
Eisai | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement | Lenvima
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payments accrued but not yet paid		600	600
Potential future sales-based milestone payments		2,600	2,600
Potential future regulatory milestone payments		50	50
Sales-based milestone payments			$ 200
Eisai | Regulatory Milestones | Lenvima
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Capitalized milestone payment		$ 75
Bayer AG | Collaborative Arrangement, Transaction with Party to Collaborative Arrangement
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestone payments accrued but not yet paid	400
Liabilities	$ 400

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