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Goodwill and Other Intangibles - Goodwill Activity by Segment (Details) - USD ($) $ in Millions | 12 Months Ended
--- | ---
Dec. 31, 2021 | Dec. 31, 2020
Goodwill [Roll Forward] |  |
Goodwill, beginning balance | $ 18,882 | $ 18,069
Acquisitions | 2,436 | 847
Divestitures |  | (54)
Other | (54) | 20
Goodwill, ending balance | 21,264 | 18,882
Accumulated goodwill impairment losses | 531 | 531
Pharmaceutical |  |
Goodwill [Roll Forward] |  |
Goodwill, beginning balance | 15,614 | 14,825
Acquisitions | 2,431 | 742
Divestitures |  | 0
Other | (48) | 47
Goodwill, ending balance | 17,997 | 15,614
Animal Health |  |
Goodwill [Roll Forward] |  |
Goodwill, beginning balance | 3,268 | 3,192
Acquisitions | 5 | 105
Divestitures |  | 0
Other | (6) | (29)
Goodwill, ending balance | 3,267 | 3,268
All Other |  |
Goodwill [Roll Forward] |  |
Goodwill, beginning balance | 0 | 52
Acquisitions | 0 | 0
Divestitures |  | (54)
Other | 0 | 2
Goodwill, ending balance | $ 0 | $ 0

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- Definition Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-03(10)(1)) -URI http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 45 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=120320667&loc=SL49117168-202975 Reference 3: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 852 -SubTopic 10 -Section 55 -Paragraph 10 -URI http://asc.fasb.org/extlink&oid=84165509&loc=d3e56426-112766 Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=99380562&loc=d3e13770-109266 + Details
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