EX-21 5 exhibit21-subsidiarylistas.htm EXHIBIT-21 SUBSIDIARY LIST
EXHIBIT 21
MERCK & CO., INC. SUBSIDIARIES
as of 12/31/2021
The following is a list of subsidiaries of the Company, doing business under the name stated.

Name | Country or State of Incorporation
7728026 Canada Inc. | Canada
Abmaxis Inc. | Delaware
Acceleron Holding Ltd. | Bermuda
Acceleron Pharma Canada Inc. | Canada (BC)
Acceleron Pharma Germany GmbH | Germany
Acceleron Pharma Inc. | Delaware
Acceleron Pharma Netherlands BV | Netherlands
Acceleron Pharma Switzerland AG | Switzerland
Acceleron Securities Corp. | Massachusetts
Afferent Pharmaceuticals, Inc. | Delaware
Agrident GmbH | Germany
Agro Verhen B.V. | Netherlands
Aleis Pty Ltd | Australia
Allflex Argentina S.A. | Argentina
Allflex Australia Pty. Ltd. | Australia
Allflex Avrasya Hayvan Kimlik Sistemleri Sanayi Ve Ticaret Limited Sirketi | Turkey
Allflex dan-mark ApS | Denmark
Allflex Europe S.A.S. | France
Allflex Group Germany GmbH | Germany
Allflex Holdings 1 Inc. | Delaware
Allflex Holdings 2 Inc. | Delaware

1

Allflex Holdings 3 Inc. | Delaware
Allflex India Private Limited | India
Allflex International do Brasil Ltda. | Brazil
Allflex Maroc S.A.R.L. | Morocco
Allflex New Zealand Limited | New Zealand
Allflex Polska Spolka z ograniczona odpowiedzialnoscia | Poland
Allflex SCR Vostok | Belarus
Allflex Services S.A.R.L. | France
Allflex UK Group Limited | United Kingdom
Allflex USA, LLC | Delaware
Alta Plastic Muhendislik Sanayi Ve Ticaret Limited Sirketi | Turkey
Animal ID Australia Pty Ltd | Australia
Antelliq Finance, Inc. | Delaware
Antelliq Holdings France S.A.S | France
Antimicrobial Stewardship LLC | Delaware
ArQule, Inc. | Delaware
Beijing Allflex Plastic Products Co. Ltd | China
Beijing Protection Science and Technology Co., Ltd. | China
Biomark, LLC | Idaho
BRC Ltd. | Bermuda
Burgwedel Biotech GmbH | Germany
Calporta Therapeutics, Inc. | Delaware
Cambridge Resonant Technologies Ltd | United Kingdom
Canji, Inc. | Delaware
cCam Biotherapeutics Ltd. | Israel
Cherokee Pharmaceuticals LLC | Delaware
Chevillot S.A.S. | France

2

Controladora MSD Mexicana Sociedad de Responsabilidad Limitada de Capital Variable | Mexico
Cooper Veterinary Products (Proprietary) Limited | South Africa
Corporation Allflex, Inc. | Canada
Cosmas B.V. | Netherlands
Cubist Pharmaceuticals LLC | Delaware
Destron Fearing Corporation | Delaware
Dialstat Trading 91 Pty Ltd T/A Allflex SA | South Africa
Digital Angel S.A. | Digital Angel S.A.
Diosynth Holding B.V. | Netherlands
Diosynth Produtos Farmo-quimicos Ltda. | Brazil
Drovers ID Pty Ltd | Australia
DSD Holding A/S | Denmark
Elastec S.R.L | Argentina
Essex Pharmaceuticals, Inc. | Philippines
Essexfarm, S.A. | Ecuador
Farmacox - Companhia Farmaceutica, Lda | Portugal
Farmasix-Produtos Farmaceuticos, Lda | Portugal
Financiere MSD | France
Fontelabor-Produtos Farmaceuticos, Lda. | Portugal
Frosst Laboratories, Inc. | Delaware
Frosst Portuguesa - Produtos Farmaceuticos, Lda. | Portugal
GlycoFi, Inc. | Delaware
GT Acquisition Sub, Inc. | Minnesota
Hangzhou MSD Pharmaceutical Co., Ltd.1 | China
Harrisvaccines, Inc. | Iowa
Hawk and Falcon L.L.C. | Delaware
Healthcare Services and Solutions, LLC | Delaware

3

Heptafarma Companhia Farmaceutica, Lda | Portugal
Hydrochemie GmbH | Germany
Idenix GmbH | Switzerland
Idenix SARL | France
IdentiGEN Canada Ltd. | Canada
IdentiGEN Czech s.r.o. | Czech Republic
IdentiGEN Deutschland GmbH | Germany
IdentiGEN Limited | Ireland
IdentiGEN North America Inc. | Delaware
IdentiGEN Switzerland AG | Switzerland
Immune Design B.V. | Netherlands
Immune Design Corp. | Delaware
Insight Acquisition Holdings Limited | Ireland
International Indemnity Ltd. | Bermuda
Intervet (Ireland) Limited | Ireland
Intervet (Israel) Ltd. | Israel
Intervet (M) Sdn. Bhd. | Malaysia
Intervet (Proprietary) Limited | South Africa
Intervet (Thailand) Ltd. | Thailand
Intervet AB | Sweden
Intervet Agencies B.V. | Netherlands
Intervet Animal Health Taiwan Limited | China
Intervet Argentina S.A. | Argentina
Intervet Australia Pty Limited | Australia
Intervet Canada Corp. | Canada
Intervet Central America S. de R.L. | Panama
Intervet Deutschland GmbH | Germany

4

Intervet Ecuador S.A. | Ecuador
Intervet Egypt for Animal Health SAE | Egypt
Intervet GesmbH | Austria
Intervet Hellas A.E. | Greece
Intervet Holding B.V. | Netherlands
Intervet Holdings France SAS | France
Intervet Hungaria Értékesítő Kft | Hungary
Intervet Inc. | Delaware
Intervet India Pvt Limited | India
Intervet International B.V. | Netherlands
Intervet International GmbH | Germany
Intervet International Sarl | France
Intervet LLC | Russian Federation
Intervet Maroc S.A. | Morocco
Intervet Mexico S.A. de C.V. | Mexico
Intervet Middle East Limited | Cyprus
Intervet Nederland B.V. | Netherlands
Intervet Philippines, Inc. | Philippines
Intervet Productions S.A. | France
Intervet Productions S.r.l. | Italy
Intervet Romania SRL | Romania
Intervet S.A. | Peru
Intervet SAS | France
Intervet Schering-Plough Animal Health Pty. Ltd. | Australia
Intervet South Africa (Proprietary) Limited | South Africa
Intervet Sp. z.o.o. | Poland
Intervet UK Production Limited | United Kingdom

5

Intervet Venezolana S.A. | Venezuela
Intervet Veterinaria Chile Ltda | Chile
Intervet Veteriner Ilaclari Pazarlama ve Ticaret Ltd. Sirketi | Turkey
Intervet, s.r.o. | Czech Republic
Interveterinaria SA de CV | Mexico
IOmet Pharma Limited | United Kingdom
Laboratoires Merck Sharp & Dohme-Chibret | France
Laboratorios Abello, S.A. | Spain
Laboratorios Chibret, S.A. | Spain
Laboratorios Frosst, S.A. | Spain
Laboratorios Quimico-Farmaceuticos Chibret, Lda | Portugal
Lemifar S. A. | Uruguay
Maya Tibbi Ürünler Ticaret Limited Sirketi | Turkey
MCM Vaccine B.V.1 | Netherlands
Merck and Company LLC | Delaware
Merck Canada Inc. | Canada
Merck Capital Ventures, LLC 1 | Delaware
Merck Frosst Canada & Co. | Canada
Merck Frosst Company | Canada
Merck Global Health Innovation Fund, LLC | Delaware
Merck Global Health Innovation, Private Equity, LLC | Delaware
Merck HDAC Research, LLC | Delaware
Merck Holdings II Corp. | Delaware
Merck Holdings III Corp. | Delaware
Merck Holdings IV Corp. | Delaware
Merck Holdings LLC | Delaware
Merck International Holdings Corp. | Delaware

6

Merck Lumira Biosciences Fund L.P.1 | Canada
Merck Registry Holdings, Inc. | New Jersey
Merck Research Investments LLC | Delaware
Merck Research Laboratories Massachusetts, LLC | Delaware
Merck Sharp & Dohme (Argentina) LLC | Delaware
Merck Sharp & Dohme (Asia) Limited | Hong Kong
Merck Sharp & Dohme (Australia) Pty. Limited | Australia
Merck Sharp & Dohme (Chile) Ltda. | Chile
Merck Sharp & Dohme (China) Limited | Hong Kong
Merck Sharp & Dohme (Enterprises) B.V. | Netherlands
Merck Sharp & Dohme (Europe) Inc. | Delaware
Merck Sharp & Dohme (Holdings) Pty Ltd | Australia
Merck Sharp & Dohme (I.A.) LLC | Delaware
Merck Sharp & Dohme (International) Limited | Bermuda
Merck Sharp & Dohme (Israel - 1996) Company Ltd. | Israel
Merck Sharp & Dohme (Malaysia) SDN. BHD. | Malaysia
Merck Sharp & Dohme (New Zealand) Limited | New Zealand
Merck Sharp & Dohme (Sweden) A.B. | Sweden
Merck Sharp & Dohme (Switzerland) GmbH | Switzerland
Merck Sharp & Dohme (UK) Limited | United Kingdom
Merck Sharp & Dohme Animal Health, S.L. | Spain
Merck Sharp & Dohme Asia Pacific Services Pte. Ltd. | Singapore
Merck Sharp & Dohme B.V. | Netherlands
Merck Sharp & Dohme BH d.o.o. | Bosnia
Merck Sharp & Dohme Bulgaria EOOD | Bulgaria
Merck Sharp & Dohme Colombia S.A.S. | Colombia
Merck Sharp & Dohme Comercializadora, S. de R.L. de C.V. | Mexico

7

Merck Sharp & Dohme Corp. | New Jersey
Merck Sharp & Dohme Cyprus Limited | Cyprus
Merck Sharp & Dohme d.o.o. | Croatia
Merck Sharp & Dohme d.o.o. Belgrade | Serbia
Merck Sharp & Dohme de Espana SAU | Spain
Merck Sharp & Dohme Farmaceutica Ltda. | Brazil
Merck Sharp & Dohme Finance Europe Limited | United Kingdom
Merck Sharp & Dohme Gesellschaft m.b.H. | Austria
Merck Sharp & Dohme Holdings Corp. | Delaware
Merck Sharp & Dohme IDEA GmbH | Switzerland
Merck Sharp & Dohme inovativna zdravila d.o.o. | Slovenia
Merck Sharp & Dohme International Services B.V. | Netherlands
Merck Sharp & Dohme Ireland (Human Health) Ltd | Ireland
Merck Sharp & Dohme Latvija | Latvia
Merck Sharp & Dohme Limitada | Bolivia
Merck Sharp & Dohme LLC | New Jersey
Merck Sharp & Dohme Manufacturing Unlimited Company | Ireland
Merck Sharp & Dohme OU | Estonia
Merck Sharp & Dohme Peru SRL | Peru
Merck Sharp & Dohme Pharmaceutical Industrial and Commercial Societe Anonyme | Greece
Merck Sharp & Dohme Research GmbH | Switzerland
Merck Sharp & Dohme Romania SRL | Romania
Merck Sharp & Dohme S.A. | Morocco
Merck Sharp & Dohme s.r.o. | Czech Republic
Merck Sharp & Dohme Salud Animal Colombia S.A.S. | Colombia
Merck Sharp & Dohme Saude Animal Ltda. | Brazil
Merck Sharp & Dohme Singapore Trading Pte. Ltd. | Singapore

8

Merck Sharp & Dohme Tunisie SARL | Tunisia
Merck Sharp & Dohme, Limitada | Portugal
Merck Sharp & Dohme, S. de R.L. de C.V. | Mexico
Merck Sharp & Dohme, s.r.o. | Slovakia
Merck Sharp Dohme Ilaclari Limited Sirketi | Turkey
Merck Teknika LLC | Delaware
Merko Acquisition S.A. | Belgium
Merko Dalton B.V. | Netherlands
Merko N.V. | Belgium
ML Holdings (Canada) Inc. | Canada
MRL San Francisco, LLC | Delaware
MRL Ventures Fund LLC | Delaware
MSD (I.A.) B.V. | Netherlands
MSD (L-SP) Unterstützungskasse GmbH | Germany
MSD (Ningbo) Animal Health Technology Co., Ltd. | China
MSD (Nippon Holdings) B.V. | Netherlands
MSD (Norge) AS | Norway
MSD (Proprietary) Limited | South Africa
MSD (Shanghai) Pharmaceuticals Consultancy Co., Ltd. | China
MSD (Thailand) Ltd. | Thailand
MSD Agencies B.V. | Netherlands
MSD AH Limited | United Kingdom
MSD Animal Health (Phils.), Inc | Philippines
MSD Animal Health (Shanghai) Trading Co., Ltd. | China
MSD Animal Health A/S | Denmark
MSD Animal Health B.V. | Belgium
MSD Animal Health Danube Biotech GmbH | Austria

9

MSD Animal Health FZ-LLC | United Arab Emirates
MSD Animal Health GmbH | Switzerland
MSD Animal Health Holdings BV | Netherlands
MSD Animal Health Innovation AS | Norway
MSD Animal Health Innovation GmbH | Germany
MSD Animal Health Innovation Pte. Ltd. | Singapore
MSD Animal Health Innovation SAS | France
MSD Animal Health K.K. | Japan
MSD Animal Health Korea Ltd. | Korea
MSD Animal Health Norge AS | Norway
MSD Animal Health Oy | Finland
MSD Animal Health Pension Trustee Limited | United Kingdom
MSD Animal Health S.r.l. | Italy
MSD Animal Health UK Ltd. | United Kingdom
MSD Animal Health Vietnam Co. Limited | Viet Nam
MSD Animal Health, Lda. | Portugal
MSD Argentina Holdings B.V. | Netherlands
MSD Argentina SRL | Argentina
MSD Asia Holdings Pte. Ltd. | Singapore
MSD Belgium BV - SRL | Belgium
MSD Biotech B.V. | Netherlands
MSD Brazil Investments B.V. | Netherlands
MSD Central America Services S. de R.L. | Panama
MSD China (Investments) B.V. | Netherlands
MSD China B.V. | Netherlands
MSD China Holding Co., Ltd. | China
MSD Cubist Holdings Unlimited Company | Ireland

10

MSD Czech Republic s.r.o. | Czech Republic
MSD Danmark ApS | Denmark
MSD Egypt LLC | Egypt
MSD EIC Unlimited Company | Ireland
MSD Eurofinance | Bermuda
MSD Farmaceutica C.A. | Venezuela
MSD FI BV | Netherlands
MSD Finance B.V. | Netherlands
MSD Finance Company | Bermuda
MSD Finance Holdings Unlimited Company | Ireland
MSD Finland Oy | Finland
MSD France | France
MSD Global Holdings B.V. | Netherlands
MSD Global Research GmbH | Switzerland
MSD HH Vietnam Ltd | Vietnam
MSD Holdings (Ireland) Unlimited Company | Ireland
MSD Holdings 2 G.K. | Japan
MSD Holdings G.K. | Japan
MSD Human Health Holding B.V. | Netherlands
MSD Human Health Holding II B.V. | Netherlands
MSD IDEA Algerie SPA | Algeria
MSD IDEA Pharmaceuticals Nigeria Limited | Nigeria
MSD IDEA Tunisie SARL | Tunisia
MSD Idenix Holdings Unlimited Company | Ireland
MSD Innovation & Development GmbH | Switzerland
MSD International B.V. | Netherlands
MSD International Business GmbH | Switzerland

11

MSD International Finance B.V. | Netherlands
MSD International Finance LLC | Delaware
MSD International GmbH | Switzerland
MSD International Investment Holdings Unlimited Company | Ireland
MSD International Manufacturing GmbH | Switzerland
MSD Investment Holdings (Ireland) Unlimited Company | Ireland
MSD Investments (Holdings) GmbH | Switzerland
MSD Italia s.r.l. | Italy
MSD Japan Holdings B.V. | Netherlands
MSD Japan Holdings GK | Japan
MSD K.K. | Japan
MSD Korea Co., Ltd. | Korea
MSD Laboratories India LLC | Delaware
MSD Latin America Services S. de R.L. | Panama
MSD Latin America Services S. de R.L. de C.V. | Mexico
MSD Limited | United Kingdom
MSD Luxembourg S.a.r.l. | Luxembourg
MSD Merck Sharp & Dohme AG | Switzerland
MSD NL 4 B.V. | Netherlands
MSD Overseas Manufacturing Co (Ireland) Unlimited Company | Ireland
MSD Panama International Services S. de R.L. | Panama
MSD Participations B.V. | Netherlands
MSD Pharma (Singapore) Pte. Ltd. | Singapore
MSD Pharma GmbH | Germany
MSD Pharma Hungary Korlatolt Felelossegu Tarsasag | Hungary
MSD Pharmaceuticals Holdings Unlimited Company | Ireland
MSD Pharmaceuticals Investments 1 Unlimited Company | Ireland

12

MSD Pharmaceuticals Investments 3 Unlimited Company | Ireland
MSD Pharmaceuticals Ireland Unlimited Company | Ireland
MSD Pharmaceuticals LLC | Russian Federation
MSD Pharmaceuticals Private Limited | India
MSD Polska Dystrybucja Sp. z.o.o. | Poland
MSD Polska Sp.z.o.o. | Poland
MSD R&D (China) Co., Ltd. | China
MSD R&D Innovation Centre Limited | United Kingdom
MSD RDC Costa Rica Sociedad de Responsabilidad Limitada | Cost Rica
MSD Regional Business Support Center GmbH | Germany
MSD Registry Holdings, Inc. | New Jersey
MSD Shared Business Services EMEA Limited | Ireland
MSD Sharp & Dohme Gesellschaft mit beschränkter Haftung | Germany
MSD Switzerland Investments 1 Unlimited Company | Ireland
MSD Switzerland Investments 4 Unlimited Company | Ireland
MSD Switzerland Investments 5 Unlimited Company | Ireland
MSD Ukraine Limited Liability Company | Ukraine
MSD Unterstutzungskasse GmbH | Germany
MSD Vaccines Limited | United Kingdom
MSD Vaccins | France
MSD Vaccins Holdings | France
MSD Venezuela Holding GmbH | Switzerland
MSD Ventures (Ireland) Unlimited Company | Ireland
MSD Verwaltungs GmbH | Germany
MSD Vietnam Company Limited | Vietnam
MSD Vietnam Holdings B.V. | Netherlands
MSD Vostok B.V. | Netherlands

13

MSDIG Holdings Unlimited Company | Ireland
MSDRG Holdings Unlimited Company | Switzerland
MSDRG LLC | Delaware
MSP Singapore Company, LLC | Delaware
MSP Vaccine Company 1 | Pennsylvania
Multilan AG | Switzerland
Nihon MSD G.K. | Japan
Nourifarma - Produtos Quimicos e Farmaceuticos, Sociedade Uniperssoal, Lda | Portugal
O.PI.VI S.R.L. | Italy
OBS Holdings B.V. | Netherlands
Oncoethix GmbH | Switzerland
OncoImmune, Inc. | Delaware
Optimer Pharmaceuticals LLC | Delaware
Organon Argentina SRL | Argentina
Organon Argentina Holdings BV | Netherlands
Organon China B.V. | Netherlands
Organon Egypt Ltd | Egypt
Organon Latin America S.A. | Uruguay
Organon Limited Liability Company | Russian Federation
Organon Middle East S.A.L. | Lebanon
OS ID AS | Norway
OS ID Hellas M.I.K.E | Greece
P.T. Merck Sharp & Dohme Indonesia | Indonesia
Pandion Therapeutics, Inc. | Delaware
Pandion Operations, Inc. | Delaware
Parlanca Limited | Ireland
Peloton Therapeutics, Inc. | Delaware

14

Polnet ID Spolka z ograniczona odpowiedzialnoscia | Poland
PrognostiX-Poultry Limited | United Kingdom
Prondil Sociedad Anónima | Uruguay
PT Intervet Indonesia | Indonesia
PT Organon Indonesia | Indonesia
PT Merck Sharp Dohme Pharma Tbk 1 | Indonesia
Putexin Investments Limited | New Zealand
Rigontec GmbH | Germany
Rigontec, Inc. | Delaware
Rosetta Inpharmatics LLC | Delaware
S.C. Allflex Romania S.R.L. | Romania
S.C.R. (Engineers) Limited | Israel
Schering-Plough, S.A.S. | France
Schering-Plough (India) Private Limited | India
Schering-Plough (Ireland) Unlimited Company | Ireland
Schering-Plough Animal Health Limited | New Zealand
Schering-Plough Canada Inc. | Canada
Schering-Plough Corporation | Philippines
Schering-Plough Corporation, U.S.A. | Delaware
Schering-Plough del Peru S.A. | Peru
Schering-Plough Holdings Limited | United Kingdom
Schering-Plough S.A. | France
Schering-Plough S.A. | Panama
Schering-Plough S.A. | Paraguay
Schering-Plough S.A. | Spain
Schering-Plough S.A. | Uruguay
Schering-Plough Sante Animale | France

15

SCR Allflex Management, Ltd | Israel
SCR Dairy, Inc. | Delaware
SCR Europe S.R.L. | Italy
SCR Monitoring Mexico, S. de R.L. de C.V. | Mexico
Sentipharm AG | Switzerland
Servicios Veternarios Servet, Sociedad Anónima | Costa Rica
Shanghai MSD Pharmaceutical Trading Co., Ltd. | China
Sistemas de Identificacao Animal Ltda | Brazil
SmartCells, Inc. | Delaware
SOL Limited | Bermuda
Stallmastaren AB | Sweden
SureFlap (NZ) Limited | New Zealand
SureFlap Limited | United Kingdom
SureFlap LLC | Florida
Tag ID Investments, Inc. | Delaware
Themis BioScience GmbH | Austria
Theriak B.V. | Netherlands
Tilos Therapeutics, Inc. | Delaware
Trius Therapeutics LLC | Delaware
UAB Merck Sharp & Dohme | Lithuania
Vaki Aquaculture Systems ehf. | Iceland
Vaki Scotland Ltd | United Kingdom
Vallée S.A.1 | Brazil
VelosBio Inc. | Delaware
VelosBio Canada Inc. | Canada
Venco Farmaceutica S.A. | Venezuela
Venco Holding GmbH | Switzerland

16

Vet Pharma Friesoythe GmbH | Germany
Veterinaria Premium, Sociedad Anonima | Guatemala
VetInvent, LLC | Delaware
Vetrex B.V. | Netherlands
Vetrex Egypt L.L.C. | Egypt
Vilsan Veteriner Ilaclari Ticaret ve Sanayi Anonim Sirketi | Turkey
Viralytics Limited | Australia
Vocaltag Limited | Israel
Vree Health Italia S.r.l. | Italy
Werthenstein Biopharma GmbH | Switzerland
Zoöpharm B.V. | Netherlands

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1 own less than 100%
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