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Goodwill and Other Intangibles - Goodwill Activity by Segment (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Goodwill [Roll Forward]    
Goodwill, beginning balance $ 18,882 $ 18,069
Acquisitions 2,436 847
Divestitures   (54)
Other (54) 20
Goodwill, ending balance 21,264 18,882
Accumulated goodwill impairment losses 531 531
Pharmaceutical    
Goodwill [Roll Forward]    
Goodwill, beginning balance 15,614 14,825
Acquisitions 2,431 742
Divestitures   0
Other (48) 47
Goodwill, ending balance 17,997 15,614
Animal Health    
Goodwill [Roll Forward]    
Goodwill, beginning balance 3,268 3,192
Acquisitions 5 105
Divestitures   0
Other (6) (29)
Goodwill, ending balance 3,267 3,268
All Other    
Goodwill [Roll Forward]    
Goodwill, beginning balance 0 52
Acquisitions 0 0
Divestitures   (54)
Other 0 2
Goodwill, ending balance $ 0 $ 0