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Financial Instruments - Information About Changes in Liabilities for Contingent Consideration (Details) $ in Millions | 3 Months Ended
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Mar. 31, 2022 USD ($) | Mar. 31, 2021 USD ($)
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] |  |
Fair value, beginning balance | $ 777 | $ 841
Changes in estimated fair value | (84) | (13)
Payments | (119) | 0
Other | (2) | (12)
Fair value, ending balance | 572 | 816
Current liability | 149 |
Contingent consideration | 572 | $ 816
Sanofi Pasteur |  |
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] |  |
Fair value, beginning balance | 620 |
Fair value, ending balance | 439 |
Contingent consideration | $ 439 |
Contingent consideration, measurement input, discount rate | 0.115 |
Measurement Input, Discount Rate | Sanofi Pasteur |  |
Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation, Calculation [Roll Forward] |  |
Contingent consideration, measurement input, discount rate | 0.08 |

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- Definition Amount of increase (decrease) in the value of a contingent consideration liability, including, but not limited to, differences arising upon settlement. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=123570139&loc=d3e3602-108585 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 4 -Subparagraph (a)(1) -URI http://asc.fasb.org/extlink&oid=120321790&loc=d3e7008-128479 + Details
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