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Segment Reporting (Tables)
3 Months Ended
Mar. 31, 2022
Segment Reporting [Abstract]  
Sales from Products
Sales of the Company’s products were as follows:
Three Months Ended March 31,
20222021
 ($ in millions)U.S.Int’lTotalU.S.Int’lTotal
Pharmaceutical:
Oncology
Keytruda$2,779 $2,030 $4,809 $2,181 $1,718 $3,899 
Alliance revenue - Lynparza (1)
141 125 266 118 110 228 
Alliance revenue - Lenvima (1)
156 71 227 85 44 130 
Alliance revenue - Reblozyl (2)
27 25 52 — — — 
Vaccines
Gardasil/Gardasil 9
418 1,042 1,460 313 604 917 
ProQuad/M-M-R II/Varivax
371 99 470 333 117 449 
RotaTeq175 41 216 118 41 158 
Pneumovax 23
118 55 173 73 99 171 
Vaqta29 36 25 34 
Hospital Acute Care
Bridion195 199 395 167 173 340 
Prevymis40 54 94 35 47 82 
Primaxin58 58 — 65 65 
Noxafil10 48 57 15 52 67 
Cancidas52 53 55 57 
Dificid49 52 25 27 
Invanz52 52 52 57 
Zerbaxa18 12 30 (2)(6)(8)
Cardiovascular
Alliance revenue - Adempas/Verquvo (3)
71 72 68 74 
Adempas— 61 61 — 55 55 
Virology
Lagevrio1,523 1,723 3,247 — — — 
Isentress/Isentress HD
61 97 158 71 138 209 
Neuroscience
Belsomra20 48 69 18 61 79 
Immunology
Simponi— 186 186 — 214 214 
Remicade— 61 61 — 85 85 
Diabetes
Januvia325 454 779 348 461 809 
Janumet63 391 454 84 401 486 
Other pharmaceutical (4)
181 339 520 212 341 554 
Total Pharmaceutical segment sales6,773 7,334 14,107 4,294 4,944 9,238 
Animal Health:
Livestock171 661 832 157 662 819 
Companion Animals302 348 650 280 319 599 
Total Animal Health segment sales473 1,009 1,482 437 981 1,418 
Total segment sales7,246 8,343 15,589 4,731 5,925 10,656 
Other (5)
93 220 312 59 (88)(29)
 $7,339 $8,563 $15,901 $4,790 $5,837 $10,627 
U.S. plus international may not equal total due to rounding.
(1)    Alliance revenue for Lynparza and Lenvima represents Merck’s share of profits, which are product sales net of cost of sales and commercialization costs (see Note 4).
(2)    Alliance revenue for Reblozyl represents royalties and a payment received related to the achievement of a regulatory milestone (see Note 4).
(3)    Alliance revenue for Adempas/Verquvo represents Merck’s share of profits from sales in Bayer’s marketing territories, which are product sales net of cost of sales and commercialization costs (see Note 4).
(4)    Other pharmaceutical primarily reflects sales of other human health pharmaceutical products, including products within the franchises not listed separately.
(5)    Other is primarily comprised of miscellaneous corporate revenues, including revenue hedging activities, as well as third-party manufacturing sales (including sales to Organon). Other for the three months ended March 31, 2022 and 2021 also includes $114 million and $56 million, respectively, related to upfront and contingent milestone payments received by Merck for out-licensing arrangements.
Consolidated Sales by Geographic Area
Consolidated sales by geographic area where derived are as follows:
Three Months Ended
March 31,
($ in millions)20222021
United States$7,339 $4,790 
Europe, Middle East and Africa4,359 3,237 
China1,143 721 
Japan989 629 
Asia Pacific (other than China and Japan)930 575 
Latin America607 500 
Other534 175 
 $15,901 $10,627 
Reconciliation of Segment Profits to Income before Taxes
A reconciliation of segment profits to Income from Continuing Operations Before Taxes is as follows:
 Three Months Ended
March 31,
($ in millions)20222021
Segment profits:
Pharmaceutical segment$9,501 $6,589 
Animal Health segment585 572 
Total segment profits10,086 7,161 
Other profits194 (50)
Unallocated:
Interest income11 
Interest expense(243)(200)
Amortization(699)(514)
Depreciation(378)(340)
Research and development(2,446)(2,305)
Restructuring costs(53)(297)
Other unallocated, net(1,607)(479)
 $4,861 $2,987